Ehrlichia chaffeensis TRP120 ubiquitinates tumor suppressor APC to modulate Hippo and Wnt signaling [PDF]
Frontiers in Cell and Developmental BiologyEhrlichia chaffeensis: TRP120 is a multifunctional effector that acts as a ligand mimic to activate evolutionary conserved eukaryotic signaling pathways Notch, Wnt, Hedgehog and Hippo.
Caitlan D. Byerly +5 more
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Evidence of Ehrlichia chaffeensis in Argentina through molecular detection in marsh deer (Blastocerus dichotomus) [PDF]
International Journal for Parasitology: Parasites and Wildlife, 2019 Vector-borne pathogens are responsible for serious emerging diseases and have been widely described in wildlife. Ehrlichia chaffeensis causes the zoonotic “monocytic ehrlichiosis” in humans, is transmitted by the tick Amblyomma americanum and its ...
Eliana C. Guillemi +3 more
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Vojnosanitetski Pregled, 2006 Background. Human ehrlichiosis is a newly recognized disease. It is a tick-borne disease caused by several bacterial species of the genhus Erlichia. These are small gram-negative pleomorphic cocci, that are obligatory intracellular bacteria.
Đokić Milomir +6 more
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Ehrlichia chaffeensis EplA Interaction With Host Cell Protein Disulfide Isomerase Promotes Infection [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 Ehrlichia chaffeensis is an obligate intracellular bacterium that invades monocytes to cause the emerging and potentially severe disease, monocytic ehrlichiosis.
Ryan S. Green +6 more
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Human Case of Ehrlichia chaffeensis Infection, Taiwan [PDF]
Emerging Infectious Diseases, 2019 In 2018, an immunosuppressed woman in southern Taiwan had onset of fever, chills, myalgia, malaise, thrombocytopenia, lymphocytopenia, and elevated hepatic transaminases. Investigation revealed infection with Ehrlichia chaffeensis.
Shih-Huan Peng +4 more
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Proteomic analysis of the Ehrlichia chaffeensis phagosome in cultured DH82 cells. [PDF]
PLoS ONE, 2014 Ehrlichia chaffeensis is an obligately intracellular bacterium that resides and multiplies within cytoplasmic vacuoles of phagocytes. The Ehrlichia-containing vacuole (ECV) does not fuse with lysosomes, an essential condition for Ehrlichia to survive ...
Yan Cheng +8 more
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BMC Genomics, 2021 Background The genus Ehrlichia consists of tick-borne obligatory intracellular bacteria that can cause deadly diseases of medical and agricultural importance. Ehrlichia sp. HF, isolated from Ixodes ovatus ticks in Japan [also referred to as I.
Mingqun Lin +12 more
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Cost effective, experimentally robust differential-expression analysis for human/mammalian, pathogen and dual-species transcriptomics. [PDF]
, 2020 As sequencing read length has increased, researchers have quickly adopted longer reads for their experiments. Here, we examine 14 pathogen or host-pathogen differential gene expression data sets to assess whether using longer reads is warranted.
Bruno, Vincent M +9 more
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Ehrlichia chaffeensis infection in the reservoir host (white-tailed deer) and in an incidental host (dog) is impacted by its prior growth in macrophage and tick cell environments. [PDF]
PLoS ONE, 2014 Ehrlichia chaffeensis, transmitted from Amblyomma americanum ticks, causes human monocytic ehrlichiosis. It also infects white-tailed deer, dogs and several other vertebrates. Deer are its reservoir hosts, while humans and dogs are incidental hosts.
Arathy D S Nair +5 more
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Comparative Analysis of Wolbachia Genomes Reveals Streamlining and Divergence of Minimalist Two-Component Systems [PDF]
, 2015 Two-component regulatory systems are commonly used by bacteria to coordinate intracellular responses with environmental cues. These systems are composed of functional protein pairs consisting of a sensor histidine kinase and cognate response regulator ...
Christensen, Steen, Serbus, Laura Renee
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