Results 21 to 30 of about 12,263 (237)

Potential zoonotic role of the tick Amblyomma cf. oblongoguttatum (Ixodida: Ixodidae) in the bacterial transmission of Ehrlichia chaffeensis (Rickettsiales: Anaplasmataceae) in a deciduous tropical forest in Mexico. [PDF]

J Med Entomol
Ehrlichia chaffeensis is a bacterium belonging to the Anaplasmataceae family. In Mexico, only 2 species have been recorded in association with tick species and humans. The objective of the present study was to detect the presence of bacteria of the genus
Guzmán-Cornejo C, Herrera-Mares A, García-Prieto L, Oceguera-Figueroa A, López-Pérez AM, Dzul-Rosado K.   +5 more
europepmc   +2 more sources

Evaluating EcxR for Its Possible Role in Ehrlichia chaffeensis Gene Regulation. [PDF]

Int J Mol Sci, 2022
Ehrlichia chaffeensis, a tick-transmitted intraphagosomal bacterium, is the causative agent of human monocytic ehrlichiosis. The pathogen also infects several other vertebrate hosts. E.
Liu H, Knox CA, Jakkula LUMR, Wang Y, Peddireddi L, Ganta RR.   +5 more
europepmc   +2 more sources

Host Cells Upregulate Phosphate Transporter PIT1 to Inhibit Ehrlichia chaffeensis Intracellular Growth. [PDF]

Int J Mol Sci
Ehrlichia chaffeensis infects and proliferates inside monocytes or macrophages and causes human monocytic ehrlichiosis (HME), an emerging life-threatening tick-borne zoonosis. After internalization, E.
Li M, Yang N, Li X, Duan N, Qin S, Wang M, Zhou Y, Jin Y, Wu W, Jin S, Cheng Z.   +10 more
europepmc   +2 more sources

Analysis of Amblyomma americanum microRNAs in response to Ehrlichia chaffeensis infection and their potential role in vectorial capacity. [PDF]

Front Cell Infect Microbiol
Background MicroRNAs (miRNAs) represent a subset of small noncoding RNAs and carry tremendous potential for regulating gene expression at the post-transcriptional level.
Kumar D, Budachetri K, Rikihisa Y, Karim S.   +3 more
europepmc   +2 more sources

Mutations in Ehrlichia chaffeensis Genes ECH_0660 and ECH_0665 Cause Transcriptional Changes in Response to Zinc or Iron Limitation. [PDF]

J Bacteriol, 2021
Ehrlichia chaffeensis, a tick-transmitted bacterium, causes human monocytic ehrlichiosis by replicating within phagosomes of monocytes/macrophages. A function disruption mutation within the pathogen’s gene encoding a phage head-to-tail connector protein ...
Torres-Escobar A, Juárez-Rodríguez MD, Ganta RR.   +2 more
europepmc   +2 more sources

Detection of Rickettsia amblyommatis and Ehrlichia chaffeensis in Amblyomma americanum Inhabiting Two Urban Parks in Oklahoma. [PDF]

Vector Borne Zoonotic Dis, 2021
For the past 30 years, the number of people infected with causative agents of ehrlichiosis, Rocky Mountain spotted fever, and spotted fever group rickettiosis (SFGR) has increased in Oklahoma.
Small M, Brennan RE.
europepmc   +2 more sources

Vaccination with an Attenuated Mutant of Ehrlichia chaffeensis Induces Pathogen-Specific CD4+ T Cell Immunity and Protection from Tick-Transmitted Wild-Type Challenge in the Canine Host. [PDF]

PLoS ONE, 2016
Ehrlichia chaffeensis is a tick-borne rickettsial pathogen and the causative agent of human monocytic ehrlichiosis. Transmitted by the Amblyomma americanum tick, E.
Jodi L McGill, Arathy D S Nair, Chuanmin Cheng, Rachel A Rusk, Deborah C Jaworski, Roman R Ganta   +5 more
doaj   +11 more sources

Insights into the mechanism regulating the differential expression of the P28-OMP outer membrane proteins in obligatory intracellular pathogen Ehrlichia chaffeensis. [PDF]

Emerg Microbes Infect, 2021
Ehrlichia chaffeensis causes human monocytic ehrlichiosis (HME), which is one of the most prevalent, life-threatening emerging infectious zoonoses. The life cycle of E. chaffeensis includes ticks and mammals, in which E.
Duan N, Ma X, Cui H, Wang Z, Chai Z, Yan J, Li X, Feng Y, Cao Y, Jin Y, Bai F, Wu W, Rikihisa Y, Cheng Z.   +13 more
europepmc   +2 more sources

Immunoreactive Protein Repertoires of Ehrlichia chaffeensis and E. canis Reveal the Dominance of Hypothetical Proteins and Conformation-Dependent Antibody Epitopes. [PDF]

Infect Immun, 2021
The immunomes of Ehrlichia chaffeensis and Ehrlichia canis have recently been revised to include immunodominant hypothetical proteins with conformational antibody epitopes. In this study, we examined 216 E. chaffeensis and 190 E.
Luo T, Patel JG, Zhang X, Walker DH, McBride JW.   +4 more
europepmc   +2 more sources

Alpha Enolase 1 Ubiquitination and Degradation Mediated by Ehrlichia chaffeensis TRP120 Disrupts Glycolytic Flux and Promotes Infection. [PDF]

Pathogens, 2021
Ehrlichia chaffeensis modulates numerous host cell processes, including gene transcription to promote infection of the mononuclear phagocyte. Modulation of these host cell processes is directed through E. chaffeensis effectors, including TRP120.
Zhu B, McBride JW.
europepmc   +2 more sources