Results 31 to 40 of about 12,137 (236)

Ehrlichia chaffeensis DNA in Haemaphysalis longicornis Ticks, Connecticut, USA. [PDF]

Emerg Infect Dis
Informed by passive tick surveillance, we collected questing Haemaphysalis longicornis ticks from southwestern Connecticut, USA. Of 445 ticks tested by PCR, 3 nymphs were positive: 1 for Ehrlichia chaffeensis and 2 for Borrelia burgdorferi.
Molaei G, Mohapatra AR, Khalil N, Cozens D, Bonilla D.   +4 more
europepmc   +2 more sources

Immunoreactive Protein Repertoires of Ehrlichia chaffeensis and E. canis Reveal the Dominance of Hypothetical Proteins and Conformation-Dependent Antibody Epitopes. [PDF]

Infect Immun, 2021
The immunomes of Ehrlichia chaffeensis and Ehrlichia canis have recently been revised to include immunodominant hypothetical proteins with conformational antibody epitopes. In this study, we examined 216 E. chaffeensis and 190 E.
Luo T, Patel JG, Zhang X, Walker DH, McBride JW.   +4 more
europepmc   +2 more sources

Ehrlichia chaffeensis TRP120 Is a Wnt Ligand Mimetic That Interacts with Wnt Receptors and Contains a Novel Repetitive Short Linear Motif That Activates Wnt Signaling. [PDF]

mSphere, 2021
Upon infecting mammalian hosts, Ehrlichia chaffeensis establishes a replicative niche in microbe-eating immune system cells where it expertly orchestrates infection and spread.
Rogan MR, Patterson LL, Byerly CD, Luo T, Paessler S, Veljkovic V, Quade B, McBride JW.   +7 more
europepmc   +2 more sources

Ehrlichia chaffeensis and Four Anaplasma Species With Veterinary and Public Health Significance Identified in Tibetan Sheep (Ovis aries) and Yaks (Bos grunniens) in Qinghai, China. [PDF]

Front Vet Sci, 2021
Tick-borne diseases (TBDs) can cause serious economic losses and are very important to animal and public health. To date, research on TBDs has been limited in Qinghai-Tibet Plateau, China.
Wang Y, Zhang Q, Han S, Li Y, Wang B, Yuan G, Zhang P, Yang Z, Zhang H, Sun Y, Chen J, Han X, He H.   +12 more
europepmc   +2 more sources

Alpha Enolase 1 Ubiquitination and Degradation Mediated by Ehrlichia chaffeensis TRP120 Disrupts Glycolytic Flux and Promotes Infection. [PDF]

Pathogens, 2021
Ehrlichia chaffeensis modulates numerous host cell processes, including gene transcription to promote infection of the mononuclear phagocyte. Modulation of these host cell processes is directed through E. chaffeensis effectors, including TRP120.
Zhu B, McBride JW.
europepmc   +2 more sources

Protein and DNA Biosynthesis Demonstrated in Host Cell-Free Phagosomes Containing Anaplasma phagocytophilum or Ehrlichia chaffeensis in Axenic Media. [PDF]

Infect Immun, 2021
Rickettsiae belong to the Anaplasmataceae family, which includes mostly tick-transmitted pathogens causing human, canine, and ruminant diseases. Biochemical characterization of the pathogens remains a major challenge because of their obligate parasitism.
Zhang Y, Chen L, Kondethimmanahalli C, Liu H, Ganta RR.   +4 more
europepmc   +2 more sources

Mutations in Ehrlichia chaffeensis Causing Polar Effects in Gene Expression and Differential Host Specificities. [PDF]

PLoS ONE, 2015
Ehrlichia chaffeensis, a tick-borne rickettsial, is responsible for human monocytic ehrlichiosis. In this study, we assessed E. chaffeensis insertion mutations impacting the transcription of genes near the insertion sites.
Chuanmin Cheng, Arathy D S Nair, Deborah C Jaworski, Roman R Ganta   +3 more
doaj   +5 more sources

Functional Characterization of Multiple Ehrlichia chaffeensis Sodium (Cation)/Proton Antiporter Genes Involved in the Bacterial pH Homeostasis. [PDF]

Int J Mol Sci, 2021
Ehrlichia chaffeensis causes human monocytic ehrlichiosis. Little is known about how this and other related tick-borne rickettsia pathogens maintain pH homeostasis in acidified phagosomes and the extracellular milieu.
Wei L, Liu H, Alizadeh K, Juarez-Rodriguez MD, Ganta RR.   +4 more
europepmc   +2 more sources

Host membrane lipids are trafficked to membranes of intravacuolar bacterium Ehrlichia chaffeensis. [PDF]

Proc Natl Acad Sci U S A, 2020
Significance Biological membranes are essential for life. Although bacteria and eukaryotic cells have evolved to produce membranes of different compositions, several bacterial pathogens can hijack and utilize host-synthesized membrane lipids.
Lin M, Grandinetti G, Hartnell LM, Bliss D, Subramaniam S, Rikihisa Y.   +5 more
europepmc   +2 more sources

Proteomic analysis of the Ehrlichia chaffeensis phagosome in cultured DH82 cells. [PDF]

PLoS ONE, 2014
Ehrlichia chaffeensis is an obligately intracellular bacterium that resides and multiplies within cytoplasmic vacuoles of phagocytes. The Ehrlichia-containing vacuole (ECV) does not fuse with lysosomes, an essential condition for Ehrlichia to survive ...
Yan Cheng, Yan Liu, Bin Wu, Jian-zhi Zhang, Jiang Gu, Ya-ling Liao, Fu-kun Wang, Xu-hu Mao, Xue-jie Yu   +8 more
doaj   +5 more sources