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New EHV‐1 variant identified

Veterinary Record, 2020
Equine herpesvirus type 1 (EHV-1) is an important threat to the equine industry worldwide. EHV-1 infection can induce respiratory disease, abortion in mares, neonatal death of foals and myeloencephalopathy (EHM). The reasons for the development of different forms of the disease remain largely unknown, but are likely to involve factors such as virus ...
Paillot, Romain, Sutton, Gabrielle, Thieulent, Côme, Marcillaud-Pitel, Christel, Pronost, Stéphane   +4 more
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Equine herpesvirus 1 (EHV-1) glycoprotein D DNA inoculation in horses with pre-existing EHV-1/EHV-4 antibody

Veterinary Microbiology, 2000
We have shown previously that equine herpesvirus 1 (EHV-1) glycoprotein D (gD) DNA elicited protective immune responses against EHV-1 challenge in murine respiratory and abortion models of EHV-1 disease. In this study, 20 horses, all with pre-existing antibody to EHV-4 and two with pre-existing antibody to EHV-1, were inoculated intramuscularly with ...
Daria N Love, James R Gilkerson, J E Wellington   +2 more
exaly   +3 more sources

Epidemiology of EHV-1 and EHV-4 in the mare and foal populations on a Hunter Valley stud farm: are mares the source of EHV-1 for unweaned foals

Veterinary Microbiology, 1999
The prevalence of EHV-1 and EHV-4 antibody-positive horses was determined using a type specific ELISA on serum samples collected from 229 mares and their foals resident on a large Thoroughbred stud farm in the Hunter Valley of New South Wales in February 1995.
James R Gilkerson, J M Whalley, D N Love   +2 more
exaly   +3 more sources

EHV-1 and EHV-4 infection in vaccinated mares and their foals

Veterinary Immunology and Immunopathology, 2006
A silent cycle of equine herpesvirus 1 infection was described following epidemiological studies of unvaccinated mares and foals on a Hunter Valley stud farm. Following the introduction of routine vaccination with an inactivated whole virus equine herpesvirus 1 (EHV-1) and equine herpesvirus 4 (EHV-4) vaccine in 1997, a subsequent study identified ...
D N Love, James R Gilkerson, J E Wellington   +2 more
exaly   +3 more sources

A nested PCR for the detection and differentiation of EHV-1 and EHV-4

Journal of Virological Methods, 1993
The nested PCR method was applied for the detection and direct differentiation of equine herpesvirus type 1 (EHV-1) and type 4 (EHV-4). Primer pairs were chosen from the glycoprotein B (gB) coding region of each serotype. The outer and inner EHV-1 primer pairs were type-specific, whereas the outer EHV-4 primer pair amplified EHV-1 and EHV-4 DNA and was
K Borchers
exaly   +3 more sources

The N-terminal glycine of EHV-1 UL11 is essential for the localization of UL11 and EHV-1 replication in cultured cells

Journal of General Virology, 2023
Equine herpesvirus type 1 (EHV-1) UL11 is a 74-amino-acid (aa) protein encoded by ORF51. UL11 is modified by acylation including myristoylation and palmitoylation. Myristoylation of EHV-1 UL11 is assumed to occur on the N-terminal glycine, while palmitoylation is assumed to occur on the seventh and ninth cysteines. ORF51, which encodes the first 24 aa,
Noriko Fukushi, Yassien Badr, Hideto Fukushi   +2 more
openaire   +2 more sources

Transmission of EHV-1 by Horses with EHV-1 Myeloencephalopathy: Implications for Biosecurity and Review

Clinical Techniques in Equine Practice, 2006
Although myeloencehalopathy due to Equine Herpesvirus-1 occurs infrequently, multiple horses may be affected during an outbreak and mortality may be high. In January of 2003, six horses from a large outbreak of EHV-1 respiratory and neurological disease were referred to The Ohio State University Veterinary Teaching Hospital for treatment of ...
Catherine W. Kohn, Stephen M. Reed, Cheryl D. Sofaly, Richard W. Henninger, William J. Saville, George P. Allen, Christopher Premanadan   +6 more
openaire   +1 more source

Equine herpesvirus type 1 (EHV-1) infection and vaccination with an inactivated EHV-1 vaccine

New Zealand Veterinary Journal, 1986
Abstract Extract Madam:- We have been investigating episodes of severe respiratory disease in foals during their first year of life in the Waikato district of New Zealand. Most foals are affected at six to ten weeks of age and again at weaning time (4) and the problem has been especially severe on one stud, ten foals having died of respiratory disease ...
Z F, Fu, A J, Robinson, L G, Dickinson, J B, Grimmett   +3 more
openaire   +2 more sources

Investigation of the role of mules as silent shedders of EHV‐1 during an outbreak of EHV‐1 myeloencephalopathy in California

Veterinary Record, 2012
EQUINE herpesvirus-1 (EHV-1) is an economically important pathogen affecting horses and exerts its major impact by inducing abortion storms or sporadic abortions in pregnant mares, early neonatal death in foals and respiratory disease in young horses (Ostlund 1993).
N, Pusterla, S, Mapes, C, Wademan, A, White, K, Estell, E, Swain   +5 more
openaire   +2 more sources

Replication of neurovirulent equine herpesvirus type 1 (EHV-1) in CD172a+ monocytic cells

Comparative Immunology, Microbiology and Infectious Diseases, 2017
Equine herpesvirus type 1 (EHV-1) is responsible for respiratory disorders, abortion and myeloencephalopathy (EHM) in horses. Two pathotypes of EHV-1 strains are circulating in the field: neurovirulent (N) and non-neurovirulent (NN).
Kathlyn Laval, Jolien Van Cleemput, Hans J Nauwynck   +2 more
exaly   +2 more sources