Results 21 to 30 of about 2,007 (161)
SERINC5 counters retroviruses and non-retroviruses [PDF]
Frontiers in Cellular and Infection MicrobiologySERINC5 (serine incorporator 5), a member of the serine incorporator family, has been identified as a retrovirus restriction factor that inhibits the fusion of virions with the plasma membrane, thus blocking the release of the viral core into target ...
Jinghua Yu +6 more
doaj +2 more sources
Assessment of Integration-defective HIV-1 and EIAV Vectors In Vitro and In Vivo
Molecular Therapy: Nucleic Acids, 2012 The interest in integrase-defective lentiviral vectors (IDLVs) stems from their potential advantage of large cloning capacity and broad cell tropism while avoiding the possibility of insertional mutagenesis.
Scott Ellis +5 more
doaj +4 more sources
EIAV encodes an accessory protein that antagonizes the host restriction factor equine tetherin [PDF]
Proceedings of the National Academy of Sciences of the United States of AmericaXiangmin Zhang, Weiwei Ma, Jiwei Li
exaly +2 more sources
ESCRT requirements for EIAV budding [PDF]
Retrovirology, 2013 Retroviruses and many other enveloped viruses usurp the cellular ESCRT pathway to bud from cells. However, the stepwise process of ESCRT-mediated virus budding can be challenging to analyze in retroviruses like HIV-1 that recruit multiple different ESCRT factors to initiate budding.In this study, we characterized the ESCRT factor requirements for ...
Sandrin, Virginie, Sundquist, Wesley I
openaire +2 more sources
Keap1 recognizes EIAV early accessory protein Rev to promote antiviral defense.
PLoS Pathogens, 2022 The Nrf2/Keap1 axis plays a complex role in viral susceptibility, virus-associated inflammation and immune regulation in host cells. However, whether or how the Nrf2/Keap1 axis is involved in the interactions between equine lentiviruses and their hosts ...
Yan Wang +10 more
doaj +1 more source
Phylogeography of Equine Infectious Anemia Virus
Frontiers in Ecology and Evolution, 2020 Equine Infectious Anemia virus (EIAV) is the causative agent of one of the most impacting infectious diseases affecting equids. EIAV is genetically diverse with several lineages circulating globally.
Manuel Jara +2 more
doaj +1 more source
Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023 Equine abortus salmonellosis is a bacterial disease that causes high abortion rates in susceptible equids and therefore significant economic losses. Although the tube agglutination test (TAT) is a commonly used serological test for S. Abortusequi, it is not highly specific or sensitive, and the development of more sensitive, specific and rapid assays ...
Kui Guo +12 more
wiley +1 more source
Genetic Evolution during the development of an attenuated EIAV vaccine [PDF]
Retrovirology, 2016 The equine infectious anemia virus (EIAV) vaccine is the only attenuated lentiviral vaccine applied on a large scale that has been shown to be effective in controlling the prevalence of EIA in China. This vaccine was developed by successive passaging of a field-isolated virulent strain in different hosts and cultivated cells.
Wang, Xue-Feng +8 more
openaire +2 more sources
Transboundary and Emerging Diseases, Volume 69, Issue 5, Page e2757-e2768, September 2022., 2022 Abstract Most animal disease surveillance systems concentrate efforts in blocking transmission pathways and tracing back infected contacts while not considering the risk of transporting animals into areas with elevated disease risk. Here, we use a suite of spatial statistics and social network analysis to characterize animal movement among areas with ...
Nicolas C. Cardenas +3 more
wiley +1 more source
Veterinary Medicine and Science, Volume 8, Issue 3, Page 1305-1310, May 2022., 2022 • Identification of some index MERS‐CoV naturally infected dromedary camel population. • A longitudinal follow‐up study for MERS‐CoV naturally infected dromedary camels based on repeated testing of nasal swabs from some animals revealed the contentious circulation of the virus in these animals throughout the duration of the study.
Maged Gomaa Hemida +4 more
wiley +1 more source