Results 141 to 150 of about 53,789 (311)

Clinical procedure for colon carcinoma tissue sampling directly affects the cancer marker-capacity of VEGF family members [PDF]

, 2012
Background: mRNA levels of members of the Vascular Endothelial Growth Factor family (VEGF-A, -B, -C, -D, Placental Growth Factor/PlGF) have been investigated as tissue-based markers of colon cancer.
Ceelen, Wim, De Craene, Bram, Grooten, Johan, Pattyn, Piet, Peeters, Marc, Pringels, Sarah, Van Damme, Nancy   +6 more
core   +2 more sources

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases [PDF]

, 2009
Long-chain polyunsaturated fatty acids (LC-PUFAs) play an important role in several physiological processes and their concentration in phospholipids has been associated with several complex diseases, such as atopic disease.
Heinrich, Joachim, Illig, Thomas, Koletzko, Berthold, Lattka, Eva   +3 more
core   +1 more source

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

The Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira, Floor Spaans, Christy‐Lynn M. Cooke, Sandra T. Davidge   +3 more
wiley   +1 more source

A novel role for activating transcription factor-2 in 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis*

Journal of Lipid Research, 2009
To investigate the mechanisms underlying 15(S)-HETE-induced angiogenesis, we have studied the role of the small GTPase, Rac1. We find that 15(S)-HETE activated Rac1 in human retinal microvascular endothelial cells (HRMVEC) in a time-dependent manner ...
Tieqiang Zhao, Dong Wang, Sergey Y. Cheranov, Manjula Karpurapu, Koteswara R. Chava, Venkatesh Kundumani-Sridharan, Dianna A. Johnson, John S. Penn, Gadiparthi N. Rao   +8 more
doaj   +1 more source

Lung eicosanoids in perinatal rats with congenital diaphragmatic hernia [PDF]

, 1997
Hanneke IJsselstijn, Freek J. Zijlstra, Jeanette P.M. Van Dijk, J.C. de Jongste, Dick Tibboel   +4 more
openalex   +1 more source

Effects of non‐steroidal anti‐inflammatory drugs and other eicosanoid pathway modifiers on antiviral and allergic responses: EAACI task force on eicosanoids consensus report in times of COVID‐19 [PDF]

, 2022
Milena Sokołowska, G. Enrico Rovati, Zuzana Diamant, Eva Untersmayr, Jürgen Schwarze, Zuzanna Łukasik, Florentina Sava, Alba Angelina, Óscar Palomares, Cezmi A. Akdiş, Liam O’Mahony, Miloš Jeseňák, Oliver Pfaar, Marı́a José Torres, Marek Sanak, Sven‐Erik Dahlén, Grzegorz Woszczek   +16 more
openalex   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

Synopsis: Special Issue on “Disruption of signaling homeostasis induced crosstalk in the carcinogenesis paradigm Epistemology of the origin of cancer”

4 open, 2019
It is increasingly evident that carcinogenesis, in the vast majority of cancers, cannot be explained simply through an accumulation of somatic mutations, or epigenetics, the stem cell theory, or the Warburg effect.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Cataloguing the Effects of Genetic Variants in 5' Upstream Regions of Eicosanoid Related Genes [PDF]

, 2015
James R. Perkins, J.A. Cornejo‐García, Inmaculada Doña, Natalia Blanca‐López, María del Carmen Plaza‐Seron, Juan A. G. Ranea, Veronique Godineau, Cristobalina Mayorga, Marı́a José Torres, Gabriela Cantó, Miguel Blanca   +10 more
openalex   +1 more source