GCN2 is activated by methyl jasmonate through GCN1 and reactive oxygen species in Arabidopsis thaliana [PDF]
Scientific ReportsPlant growth and productivity rely on rapid energy management strategies to adapt dynamic environments. Previous work in Arabidopsis thaliana identified a fast-regulatory switch linking cytosolic translation and reactive oxygen species (ROS) signaling ...
Daniel Rincon Diaz +4 more
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Zhongguo shipin weisheng zazhi, 2023 ObjectiveTo study the cardioprotective effect of sesame ethanol extract （SEE） on exercise-induced fatigue （EIF） rats and its effects on myocardial physiological and biochemical parameters.MethodsRats were randomly divided into control group （Control ...
LI Qiang, MAO Yufeng
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The Effects of Glyburide on Apoptosis and Endoplasmic Reticulum Stress in INS-1 Cells in a Glucolipotoxic Condition [PDF]
Diabetes & Metabolism Journal, 2011 Backgroundβ-cell death due to endoplasmic reticulum (ER) stress has been regarded as an important pathogenic component of type 2 diabetes. The possibility has been suggested that sulfonylurea, currently being used as one of the main oral hypoglycemic ...
Min Jeong Kwon +10 more
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Curcumin: a bioactive compound with molecular targets for human malignancies
Food and Agricultural Immunology, 2023 Cancer is the second leading cause of death in the world and one of the major public health problems. Curcumin has anticancer activity including inducing apoptosis and inhibiting proliferation and invasion of tumours by suppressing a variety of cellular ...
Muhammad Shahbaz +12 more
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Gefitinib and Erlotinib Lead to Phosphorylation of Eukaryotic Initiation Factor 2 Alpha Independent of Epidermal Growth Factor Receptor in A549 Cells. [PDF]
PLoS ONE, 2015 Gefitinib and erlotinib are anticancer agents, which inhibit epidermal growth factor receptor (EGFR) tyrosine kinase. Interstitial lung disease (ILD) occurs in patients with non-small cell lung cancer receiving EGFR inhibitors.
Satoshi Koyama +7 more
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Regulation of the interactions between human eIF5 and eIF1A by the CK2 kinase
Current Research in Structural Biology, 2022 Translation initiation in eukaryotes relies on a complex network of interactions that are continuously reorganized throughout the process. As more information becomes available about the structure of the ribosomal preinitiation complex (PIC) at various ...
Nathan Gamble +3 more
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PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis. [PDF]
PLoS ONE, 2007 TOR (Target of Rapamycin) is a highly conserved protein kinase and a central controller of cell growth. TOR is found in two functionally and structurally distinct multiprotein complexes termed TOR complex 1 (TORC1) and TOR complex 2 (TORC2).
Kathrin Thedieck +7 more
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Characterization and QTL Mapping of a Major Field Resistance Locus for Bacterial Blight in Rice
Plants, 2022 Bacterial blight (BB) disease, caused by Xanthomonas oryzae pv. oryzae (Xoo), is among the major factors that can cause rice yields to decrease. To address BB disease, researchers have been looking for ways to change pesticides and cultivation methods ...
Jae-Ryoung Park +6 more
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Effects of Dietary Crude Protein Levels and Cysteamine Supplementation on Protein Synthetic and Degradative Signaling in Skeletal Muscle of Finishing Pigs. [PDF]
PLoS ONE, 2015 Dietary protein levels and cysteamine (CS) supplementation can affect growth performance and protein metabolism of pigs. However, the influence of dietary protein intake on the growth response of CS-treated pigs is unclear, and the mechanisms involved in
Ping Zhou +9 more
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International Journal of Inflammation, 2014 The intensities of macrophage inflammatory responses to bacterial components gradually decrease with age. Given that a reduced rate of protein synthesis is a common age-related biochemical change, which is partially mediated by increased phosphorylation ...
Ken Shirato, Kazuhiko Imaizumi
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