Results 111 to 120 of about 35,642 (231)

Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation [PDF]

, 2013
Abhay P. S. Rathore, Mah Lee Ng, Subhash G. Vasudevan   +2 more
openalex   +1 more source

Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death. [PDF]

, 2019
学位記番号 ...
Shibusawa, Ryo, シブサワ, リョウ, 澁澤, 良   +2 more
core  

Deficient Cardiolipin Remodelling Alters Muscle Fibre Composition and Neuromuscular Connectivity in Barth Syndrome

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Barth syndrome (BTHS) is a rare X‐linked mitochondrial disorder caused by mutations in the TAFAZZIN gene, which disrupts cardiolipin (CL) remodelling and mitochondrial function. While cardiac manifestations of BTHS are well characterized in male patients, the mechanisms underlying skeletal muscle weakness and fatigability are poorly
Catalina Matias, Paige L. Snider, Elizabeth A. Sierra Potchanant, Joshua R. Huot, Rahul Raghav, Michael T. Chin, Simon J. Conway, Jeffrey J. Brault   +7 more
wiley   +1 more source

PfeIK1, a eukaryotic initiation factor 2α kinase of the human malaria parasite Plasmodium falciparum, regulates stress-response to amino-acid starvation

Malaria Journal, 2009
Background Post-transcriptional control of gene expression is suspected to play an important role in malaria parasites. In yeast and metazoans, part of the stress response is mediated through phosphorylation of eukaryotic translation initiation factor 2α
Ranford-Cartwright Lisa, Wilkes Jonathan, Russo Ilaria, Babbitt Shalon, Fennell Clare, Goldberg Daniel E, Doerig Christian   +6 more
doaj   +1 more source

Supplementary Figure S3 from Estrogen-Induced Apoptosis in Breast Cancers Is Phenocopied by Blocking Dephosphorylation of Eukaryotic Initiation Factor 2 Alpha (eIF2α) Protein

, 2023
Surojeet Sengupta, Catherine M. Sevigny, Poulomi Bhattacharya, V. Craig Jordan, Robert Clarke   +4 more
openalex   +1 more source

ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression. [PDF]

, 2019
The c-Myc oncogene drives malignant progression and induces robust anabolic and proliferative programmes leading to intrinsic stress. The mechanisms enabling adaptation to MYC-induced stress are not fully understood.
Amaravadi, Ravi K, Chinga, Frank, Conn, Crystal S, Diehl, J Alan, Fu, Weixuan, Fuchs, Serge Y, Ignatova, Zoya, Kossenkov, Andrew, Koumenis, Constantinos, Leli, Nektaria Maria, Monroy, Alexandra M, Ojha, Rani, Polte, Christine, Ruggero, Davide, Salas Salinas, Carlo, Tameire, Feven, Verginadis, Ioannis I, Wang, Paul, Ye, Jiangbin   +18 more
core  

Inhibition of N‐Terminal Acetyltransferase C Mitigates Endoplasmic Reticulum Stress–Mediated Muscle Atrophy in Cancer Cachexia

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Cancer cachexia is a complex syndrome marked by weight loss and muscle wasting, significantly impacting patient quality of life and survival. Mechanistically, it is characterized by suppressed protein synthesis and enhanced muscle catabolism, with the role of endoplasmic reticulum (ER) stress and unfolded protein response (UPR ...
Yusaku Kaneko, Tomohiro Hino, Shunta Taminishi, Yayoi Matoba, Daisuke Motooka, Atsushi Hoshino, Satoaki Matoba   +6 more
wiley   +1 more source

Supplementary Figures from Epithelial-to-Mesenchymal Transition Activates PERK–eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress

, 2023
Yuxiong Feng, Ethan S. Sokol, Catherine Del Vecchio Fitz, Sandhya Sanduja, Jasper H.L. Claessen, Theresa A. Proia, Dexter X. Jin, Ferenc Reinhardt, Hidde L. Ploegh, Qiu Wang, Piyush B. Gupta   +10 more
openalex   +2 more sources

A retrograde GCN2/eIF2α, but ATF4 independent, mechanism maintains synaptic strength under acute amino acid scarcity at the NMJ [PDF]

, 2022
Grant Kauwe, Megumi Mori, Edward H. Liao, Gary K. Scott, A. Pejmun Haghighi   +4 more
openalex   +1 more source

Weight Loss During Obesity Provokes Asparaginase‐Associated Liver Steatosis and Endoplasmic Reticulum Stress

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Lean mice and DIO mice were fed either a low‐fat maintenance diet (MD) or a high‐fat obesogenic diet (OD) during pegylated asparaginase exposure. OD exacerbated asparaginase‐induced weight loss and modestly increased liver triglycerides and ER stress in lean mice.
Chintan T. Bhavsar, Brian A. Zalma, Keigo Tomoo, Yi Zhang, Esther M. Lopez, Emily T. Mirek, Joseph L. Dixon, Gregory C. Henderson, Ronald C. Wek, Tracy G. Anthony   +9 more
wiley   +1 more source