Results 1 to 10 of about 113,337 (338)

Targeted delivery of pentagalloyl glucose inhibits matrix metalloproteinase activity and preserves elastin in emphysematous lungs

Respiratory Research, 2021
Background Elastin degradation has been established as one of the driving factors of emphysema. Elastin-derived peptides (EDPs) are shown to act as a chemoattractant for monocytes.
Vaideesh Parasaram, Xiaoying Wang, Pantrika Krisanarungson, Narendra Vyavahare   +3 more
doaj   +1 more source

Assessment of Stromal Elastin Fibers in Breast Cancer and Fibroadenomas: Is There a Correlation With Ultrasound Elastography Findings?

European Journal of Breast Health, 2022
Objective:The stiffness of a breast lesion provides information on the likelihood of malignancy. The most important factor affecting this stiffness is the composition of the extracellular matrix (ECM).
Nurşen Toprak, İbrahim Aras, Osman Toktaş, Adem Yokuş, Ali Mahir Gündüz   +4 more
doaj   +1 more source

The effect of static stretch on elastin degradation in arteries. [PDF]

PLoS ONE, 2013
Previously we have shown that gradual changes in the structure of elastin during an elastase treatment can lead to important transition stages in the mechanical behavior of arteries.
Ming-Jay Chow, Myunghwan Choi, Seok Hyun Yun, Yanhang Zhang   +3 more
doaj   +1 more source

Elastin Fiber Accumulation in Liver Correlates with the Development of Hepatocellular Carcinoma. [PDF]

PLoS ONE, 2016
The fibrosis stage, which is evaluated by the distribution pattern of collagen fibers, is a major predictor for the development of hepatocellular carcinoma (HCC) for patients with hepatitis C.
Yutaka Yasui, Tokiya Abe, Masayuki Kurosaki, Mayu Higuchi, Yasuyuki Komiyama, Tsubasa Yoshida, Tsuguru Hayashi, Konomi Kuwabara, Kenta Takaura, Natsuko Nakakuki, Hitomi Takada, Nobuharu Tamaki, Shoko Suzuki, Hiroyuki Nakanishi, Kaoru Tsuchiya, Jun Itakura, Yuka Takahashi, Akinori Hashiguchi, Michiie Sakamoto, Namiki Izumi   +19 more
doaj   +1 more source

A Study of Combining Elastin in the Chitosan Electrospinning to Increase the Mechanical Strength and Bioactivity

Marine Drugs, 2021
While electrospun chitosan membranes modified to retain nanofibrous morphology have shown promise for use in guided bone regeneration applications in in vitro and in vivo studies, their mechanical tear strengths are lower than commercial collagen ...
Hengjie Su, Tomoko Fujiwara, Joel D. Bumgardner   +2 more
doaj   +1 more source

Elastin is responsible for the rigidity of the ligament under shear and rotational stress: a mathematical simulation study

Journal of Orthopaedic Surgery and Research, 2023
Background An accurate understanding of the mechanical response of ligaments is important for preventing their damage and rupture. To date, ligament mechanical responses are being primarily evaluated using simulations.
Yuki Naya, Hiroki Takanari
doaj   +1 more source

Visualization of elastin using cardiac magnetic resonance imaging after myocardial infarction as inflammatory response

Scientific Reports, 2021
The aim of this study was to investigate the merits of magnetic resonance imaging (MRI) using an elastin-binding contrast agent after myocardial infarction in mouse models with deletions of monocyte populations.
Britta Elkenhans, Andrea Protti, Ajay Shah, David Onthank, René Botnar   +4 more
doaj   +1 more source

De Novo Synthesis of Elastin by Exogenous Delivery of Synthetic Modified mRNA into Skin and Elastin-Deficient Cells

Molecular Therapy: Nucleic Acids, 2018
Elastin is one of the most important and abundant extracellular matrix (ECM) proteins that provide elasticity and resilience to tissues and organs, including vascular walls, ligaments, skin, and lung.
Mario Lescan, Regine Mariette Perl, Sonia Golombek, Martin Pilz, Ludmilla Hann, Mahua Yasmin, Andreas Behring, Timea Keller, Andrea Nolte, Franziska Gruhn, Efrat Kochba, Yotam Levin, Christian Schlensak, Hans Peter Wendel, Meltem Avci-Adali   +14 more
doaj   +1 more source

Recent Advances in Elastin-Based Biomaterial

Journal of Pharmacy & Pharmaceutical Sciences, 2020
Elastin is one of the main components of the extracellular matrix; it provides resistance and elasticity to a variety of tissues and organs of the human body, besides participating in cellular signaling.
María Luisa Del Prado Audelo, Néstor Mendoza-Muñoz, Lidia Escutia-Guadarrama, David Giraldo-Gomez, Maykel González-Torres, Benjamín Florán, Hernán Cortés, Gerardo Leyva-Gomez   +7 more
doaj   +1 more source

Elastin Expression in Sacrouterina Ligament is Weaker in the Women with Pelvic Organ Prolapse

Indonesian Journal of Obstetrics and Gynecology, 2012
Objective: The research aims at comparing the elastin immunolabeling in the uterosacral ligaments in women with pelvic organ prolapse and without pelvic organ prolapse (POP). Methods: The research is done at Dr.
Andi Hasnawati
doaj   +1 more source