Results 81 to 90 of about 14,557 (201)

Generation of a Monoclonal Antibody to Detect Elastin-like Polypeptides

Biomacromolecules, 2019
The identification and use of antibodies dominate the biologic, clinical diagnostic, and therapeutic landscapes. In particular, antibodies have become essential tools in a variety of protein analytical experiments and to study the disposition of biologic therapeutics.
Aida Kouhi, Zhiyuan Yao, Long Zheng, Zhe Li, Peisheng Hu, Alan L. Epstein, J. Andrew MacKay   +6 more
openaire   +3 more sources

Synthesis of artificial dental enamel by an elastin-like polypeptide assisted biomimetic approach

, 2018
The synthesized artificial enamel assisted by an elastin-like polypeptide revealed a similar structure and excellent mechanical properties to those of natural enamel.
Jiang Chang, Yang Zhou, Yanling Zhou, Long Gao, Chengtie Wu   +4 more
core   +1 more source

Optimization of PET Expression Vector for Fusion of Recombinant Protein and Elastin-Like Polypeptide Biopolymer

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2019
Background and Aim recombinant DNA technique is a powerful and appropriate method for the production of protein biopolymers with specificity in amino acid sequence and spatial chemistry.
Mohammad Reza Soleyman, Mostafa Khalili, Alireza Soleyman Meiguni, Maryam Baazm   +3 more
doaj  

Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley   +1 more source

The Polymers of Life: Exploring Cellular Function Through Polymer Concepts

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Biomolecular phase separation reveals that a hidden layer of cellular organization is governed by the principles of polymer science. This review bridges polymer physics and cell biology, offering a primer on fundamental concepts, proposing a framework for interrogating cellular function, and synthesizing biophysical methods for decoding macromolecular ...
Mark Chen, Ashutosh Chilkoti
wiley   +1 more source

Sensing and Communicating β‐Cell Stress in the Context of T1D Etiology: New Opportunities for Therapeutic Impact

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Type 1 diabetes (T1D) results from the immune‐mediated destruction of insulin‐producing pancreatic β‐cells. Recent human studies show that early β‐cell stress maladaptations precede overt immune cell infiltration. DOC2B, a vesicle secretion regulatory protein that supports β‐cell functionality and resilience against stress, declines early in T1D ...
Diana Esparza, Chathurani S. Jayasena, Tijana Jovanovic‐Talisman, Debbie C. Thurmond   +3 more
wiley   +1 more source

Design and production of a chimeric resilin-, elastin-, and collagen-like engineered polypeptide.

, 2011
Protein-inspired biomaterials have gained great interest as an alternative to synthetic polymers, in particular, for their potential use as biomedical devices.
Marletta, Giovanni, BRACALELLO, Angelo, A. Pepe, Valentina Santopietro, Vassalli, Massimo, B. Bochicchio, Giovanni Marletta, Rosanna Del Gaudio, A. Bracalello, R. D. Gaudio, G. Marletta, V. Santopietro, PEPE, Antonietta, Brigida Bochicchio, Massimo Vassalli, M. Vassalli, BOCHICCHIO, Brigida, Angelo Bracalello, Antonietta Pepe, SANTOPIETRO, VALENTINA, DEL GAUDIO, ROSANNA   +20 more
core   +1 more source

Extending the Three-Dimensional Culture of Adipocytes Through Surface Coatings

Bioengineering
To mimic the important features of progressing adiposity, in vitro adipose cell culture models must allow gradual intracellular fat accumulation in the three-dimensional (3D) arrangement of adipose-derived stem cells (ASCs) over a long-term culture ...
Sheetal Chowdhury, Komal Beeton, Zacchaeus Wallace, Maggie Moore, Gene L. Bidwell, Amol V. Janorkar   +5 more
doaj   +1 more source

Thermally targeted delivery of a c-Myc inhibitory polypeptide inhibits tumor progression and extends survival in a rat glioma model. [PDF]

PLoS ONE, 2013
Treatment of glioblastoma is complicated by the tumors' high resistance to chemotherapy, poor penetration of drugs across the blood brain barrier, and damaging effects of chemotherapy and radiation to normal neural tissue.
Gene L Bidwell, Eddie Perkins, Joshua Hughes, Majid Khan, Judy R James, Drazen Raucher   +5 more
doaj   +1 more source

Respiratory Biomarkers: An Opportunity for Patient‐Centric Microsampling Approach for Treatment Optimization

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
Overview of patient centric microsampling approach for monitoring respiratory biomarkers for treatment optimization. Image created in BioRender. Khan, A. (2026) https://BioRender.com/17jm5cs. ABSTRACT The clinical heterogeneity of respiratory disorders emphasizes the need for personalized approaches to prevention, diagnosis, and therapy.
Ahmar Khan, Jacqueline L. Stair, Daniel Baker, Neil Spooner, Darragh Murnane   +4 more
wiley   +1 more source