Results 91 to 100 of about 6,079 (163)

Fusion of cell-penetrating peptides to thermally responsive biopolymer improves tumor accumulation of p21 peptide in a mouse model of pancreatic cancer

Drug Design, Development and Therapy, 2014
Leslie R Walker,1 Jung Su Ryu,1 Eddie Perkins,2 Lacey R McNally,3 Drazen Raucher1 1Department of Biochemistry, 2Department of Neurosurgery, University of Mississippi Medical Center, Jackson, MS, USA; 3Division of Hematology and Oncology, University of ...
Walker LR, Ryu JS, Perkins E, McNally LR, Raucher D   +4 more
doaj  

Engineered Elastin‐Like Polypeptides: Intelligent Self‐Assembling Platforms for Biomedical Application

Small Structures
Elastin‐like polypeptides (ELPs), genetically programmable biomaterials derived from natural tropoelastin, exhibit unique reversible self‐assembly and aggregation behaviors driven by sequence‐encoded phase transitions.
Yang Yuan, Chen Zeng, Zichun Chen, Zhuoga Ciren, Qinran Yu, Chuanbo Wang, Hui Mao, Gang Li, Weizhi Chen, Xiqun Jiang   +9 more
doaj   +1 more source

Robust Photocontrol of Elastin-like Polypeptide Phase Transition with a Genetically Encoded Arylazopyrazole. [PDF]

ACS Synth Biol, 2023
Strugach DS, Hadar D, Amiram M.
europepmc   +1 more source

Characterization of a Chimeric Resilin-Elastin Structural Protein Dedicated to 3D Bioprinting as a Bioink Component

Nanomaterials
In this study we propose to use for bioprinting a bioink enriched with a recombinant RE15mR protein with a molecular weight of 26 kDa, containing functional sequences derived from resilin and elastin.
Violetta Cecuda-Adamczewska, Agnieszka Romanik-Chruścielewska, Katarzyna Kosowska, Natalia Łukasiewicz, Iwona Sokołowska, Paulina Korycka, Katarzyna Florys-Jankowska, Agnieszka Zakrzewska, Michał Wszoła, Marta Klak   +9 more
doaj   +1 more source

Elastin-like polypeptide delivery of anti-inflammatory peptides to the brain following ischemic stroke. [PDF]

FASEB J, 2023
Howell JA, Gaouette N, Lopez M, Burke SP, Perkins E, Bidwell GL.   +5 more
europepmc   +1 more source

Elasticity Modification of Biomaterials Used in 3D Printing with an Elastin–Silk-like Recombinant Protein

Journal of Functional Biomaterials
The recombinant structural protein described in this study was designed based on sequences derived from elastin and silk. Silk–elastin hybrid copolymers are characterized by high solubility while maintaining high product flexibility. The phase transition
Violetta Cecuda-Adamczewska, Agnieszka Romanik-Chruścielewska, Katarzyna Kosowska, Iwona Sokołowska, Natalia Łukasiewicz, Paulina Korycka, Katarzyna Florys-Jankowska, Agnieszka Zakrzewska, Michał Wszoła, Marta Klak   +9 more
doaj   +1 more source

αB-Crystallin Peptide Fused with Elastin-like Polypeptide: Intracellular Activity in Retinal Pigment Epithelial Cells Challenged with Oxidative Stress. [PDF]

Antioxidants (Basel), 2023
Attia SA, Truong AT, Phan A, Lee SJ, Abanmai M, Markanovic M, Avila H, Luo H, Ali A, Sreekumar PG, Kannan R, MacKay JA.   +11 more
europepmc   +1 more source

A Simple Generic Model of Elastin–Like Polypeptides with Proline Isomerization

Macromolecular Rapid Communications
AbstractA generic model of elastin–like polypeptides (ELP) is derived that includes proline isomerization (ProI). As a case study, conformational transition of a –[valine–proline–glycine–valine–glycine]– sequence is investigated in aqueous ethanol mixtures.
Yani Zhao, Robinson Cortes–Huerto, Debashish Mukherji   +2 more
openaire   +3 more sources

Induced Chirality in QDs Using Thermoresponsive Elastin-Like Polypeptides

Langmuir
Circular dichroism (CD) spectroscopy has emerged as a potent tool for probing chiral small molecule ligand exchange on natively achiral quantum dots (QDs). In this study, we report a novel approach to identifying QD-biomolecule interactions by inducing chirality in CdS QDs using thermoresponsive elastin-like polypeptides (ELPs) engineered with C ...
Christopher D. Lowe, Helen C. Larson, Yifeng Cai, Huat Thart Chiang, Lilo D. Pozzo, François Baneyx, Brandi M. Cossairt   +6 more
openaire   +2 more sources

Engineered elastin-like polypeptide improves the efficiency of adipose-derived stem cell-mediated cutaneous wound healing in type II diabetes mellitus. [PDF]

Heliyon, 2023
Woo SH, Choi JH, Mo YJ, Lee YI, Jeon WB, Lee YS.   +5 more
europepmc   +1 more source