Dill extract induces elastic fiber neosynthesis and functional improvement in the ascending aorta of aged mice with reversal of age-dependent cardiac hypertrophy and involvement of lysyl oxidase-like-1 [PDF]
, 2020 Elastic fibers (90% elastin, 10% fibrillin-rich microfibrils) are synthesized only in early life and adolescence mainly by the vascular smooth muscle cells through the cross-linking of its soluble precursor, tropoelastin.
Boyle, Walter A +7 more
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Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries [PDF]
, 2017 Homozygous or compound heterozygous mutations in fibulin-4 (FBLN4) lead to autosomal recessive cutis laxa type 1B (ARCL1B), a multisystem disorder characterized by significant cardiovascular abnormalities, including abnormal elastin assembly, arterial ...
Broekelmann, Thomas J +5 more
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Molecular Therapy: Nucleic Acids, 2018 Elastin is one of the most important and abundant extracellular matrix (ECM) proteins that provide elasticity and resilience to tissues and organs, including vascular walls, ligaments, skin, and lung.
Mario Lescan +14 more
doaj +1 more source
Scientific Reports, 2021 The aim of this study was to investigate the merits of magnetic resonance imaging (MRI) using an elastin-binding contrast agent after myocardial infarction in mouse models with deletions of monocyte populations.
Britta Elkenhans +4 more
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Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development [PDF]
, 2018 Lung alveolarization requires precise coordination of cell growth with extracellular matrix (ECM) synthesis and deposition. The role of extracellular matrices in alveogenesis is not fully understood, because prior knowledge is largely extrapolated from ...
Chen, Hui +9 more
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Recent Advances in Elastin-Based Biomaterial
Journal of Pharmacy & Pharmaceutical Sciences, 2020 Elastin is one of the main components of the extracellular matrix; it provides resistance and elasticity to a variety of tissues and organs of the human body, besides participating in cellular signaling.
María Luisa Del Prado Audelo +7 more
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Influence of homocysteine on the physical structure and molecular mobility of elastin network in cultured arteries [PDF]
, 2009 The thermal and dielectric properties of the elastin network were investigated in arteries cultured with physiological and pathological concentrations of homocysteine, an aminoacid responsible of histological impairments in human arteries.
Chareyre, Corinne +6 more
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Analysis of the molecular mobility of collagen and elastin in safe, atheromatous and aneurysmal aortas [PDF]
, 2012 Aim of the study : In this study, we propose to use a thermal technique, Differential Scanning Calorimetry (DSC) to follow the evolution of elastin and collagen in safe and pathological cardiovascular tissues.
Dandurand, Jany +7 more
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The changes in chemical composition during development of the bovine nuchal ligament [PDF]
, 1967 Whole bovine nuchal ligaments, or portions thereof (in the case of commercially valuable animals), were obtained from 45 animals (28 fetal and 17 postnatal) ranging in age from 110 days of gestation to 10 yr. Insoluble elastin was quantitatively prepared
Cleary, E. G. +2 more
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Elastin Expression in Sacrouterina Ligament is Weaker in the Women with Pelvic Organ Prolapse
Indonesian Journal of Obstetrics and Gynecology, 2012 Objective: The research aims at comparing the elastin immunolabeling in the uterosacral ligaments in women with pelvic organ prolapse and without pelvic organ prolapse (POP). Methods: The research is done at Dr.
Andi Hasnawati
doaj +1 more source