Results 11 to 20 of about 117,981 (354)

Elastin in the Pathogenesis of Abdominal Aortic Aneurysm [PDF]

open access: yesCells
Abdominal aortic aneurysms (AAAs) are progressive, life-threatening vascular disorders characterized by focal dilation of the abdominal aorta due to chronic weakening of the arterial wall.
Dunpeng Cai, Shi-You Chen
doaj   +2 more sources

Bioactive recombinant human elastin gel for reconstructing elastic fibers and rejuvenating endogenously aged skin [PDF]

open access: yesMaterials Today Bio
Endogenous skin aging results in oxidative stress and degradation of elastic fibers, leading to reduced skin elasticity and dermal laxity. Current treatments rarely target elastic fiber regeneration.
Yi Yang   +5 more
doaj   +2 more sources

Influence of aging on dermal elastin fiber architecture and skin firmness assessed by finite element modeling [PDF]

open access: yesScientific Reports
Skin firmness and elasticity are largely determined by the dermal extracellular matrix, particularly the elastin fiber network. Age-related degradation of elastin alters its architecture, contributing to diminished skin resilience.
Fei Jiang   +6 more
doaj   +2 more sources

Expression of extracellular matrix protein in advanced keratoconus and the normal human cornea [PDF]

open access: yesFrontiers in Medicine
BackgroundThe pre-Descemet layer (Dua’s layer) (PDL/DL) and the Descemet membrane (DM) have the highest expression of elastin in normal corneas. Reduced expression of elastin occurs in the corneal stroma of patients with keratoconus (KC).
Fatima Habroosh   +10 more
doaj   +2 more sources

Spatial distribution and network morphology of epicardial, endocardial, interstitial, and Purkinje cell-associated elastin fibers in porcine left ventricle

open access: yesBioactive Materials, 2023
Cardiac extracellular matrices (ECM) play crucial functional roles in cardiac biomechanics. Previous studies have mainly focused on collagen, the major structural ECM in heart wall. The role of elastin in cardiac mechanics, however, is poorly understood.
Xiaodan Shi   +15 more
doaj   +1 more source

Targeted delivery of pentagalloyl glucose inhibits matrix metalloproteinase activity and preserves elastin in emphysematous lungs

open access: yesRespiratory Research, 2021
Background Elastin degradation has been established as one of the driving factors of emphysema. Elastin-derived peptides (EDPs) are shown to act as a chemoattractant for monocytes.
Vaideesh Parasaram   +3 more
doaj   +1 more source

Fabricated Elastin [PDF]

open access: yesAdvanced Healthcare Materials, 2015
The mechanical stability, elasticity, inherent bioactivity, and self‐assembly properties of elastin make it a highly attractive candidate for the fabrication of versatile biomaterials. The ability to engineer specific peptide sequences derived from elastin allows the precise control of these physicochemical and organizational characteristics, and ...
Giselle C, Yeo   +5 more
openaire   +3 more sources

Comparisons of the effects of silk elastin and collagen sponges on wound healing in murine models

open access: yesRegenerative Therapy, 2023
Introductions: Silk elastin, a recombinant protein with repeats of elastin and silk fibroin, possesses a self-gelling ability and is a potential wound dressing material.
Eiichi Sawaragi   +9 more
doaj   +1 more source

Assessment of Stromal Elastin Fibers in Breast Cancer and Fibroadenomas: Is There a Correlation With Ultrasound Elastography Findings?

open access: yesEuropean Journal of Breast Health, 2022
Objective:The stiffness of a breast lesion provides information on the likelihood of malignancy. The most important factor affecting this stiffness is the composition of the extracellular matrix (ECM).
Nurşen Toprak   +4 more
doaj   +1 more source

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