Results 41 to 50 of about 10,979,485 (217)

Allergens of the urushiol family promote mitochondrial dysfunction by inhibiting the electron transport at the level of cytochromes b and chemically modify cytochrome c1

Biological Research, 2021
Background Urushiols are pro-electrophilic haptens that cause severe contact dermatitis mediated by CD8+ effector T-cells and downregulated by CD4+ T-cells.
Rodrigo Pacheco, Sergio A. Quezada, Alexis M. Kalergis, María Inés Becker, Jorge Ferreira, Alfredo E. De Ioannes   +5 more
doaj   +1 more source

Tissue-specific mitochondrial HIGD1C promotes oxygen sensitivity in carotid body chemoreceptors

eLife, 2022
Mammalian carotid body arterial chemoreceptors function as an early warning system for hypoxia, triggering acute life-saving arousal and cardiorespiratory reflexes. To serve this role, carotid body glomus cells are highly sensitive to decreases in oxygen
Alba Timón-Gómez, Alexandra L Scharr, Nicholas Y Wong, Erwin Ni, Arijit Roy, Min Liu, Julisia Chau, Jack L Lampert, Homza Hireed, Noah S Kim, Masood Jan, Alexander R Gupta, Ryan W Day, James M Gardner, Richard JA Wilson, Antoni Barrientos, Andy J Chang   +16 more
doaj   +1 more source

Redox-Mediated Regulation of Mitochondrial Biogenesis, Dynamics, and Respiratory Chain Assembly in Yeast and Human Cells

Frontiers in Cell and Developmental Biology, 2021
Mitochondria are double-membrane organelles that contain their own genome, the mitochondrial DNA (mtDNA), and reminiscent of its endosymbiotic origin.
Stefan Geldon, Erika Fernández-Vizarra, Kostas Tokatlidis   +2 more
doaj   +1 more source

Respiratory chain complexes in dynamic mitochondria display a patchy distribution in life cells [PDF]

, 2010
Background: Mitochondria, the main suppliers of cellular energy, are dynamic organelles that fuse and divide frequently. Constraining these processes impairs mitochondrial is closely linked to certain neurodegenerative diseases.
Strecker, V., Busch, K., Winfried Haase, Wittig, I., Bereiter-Hahn, Jürgen, Haase, W., Karin Busch, Joos, Friederike, Ilka Wittig, Britta Muster, Jürgen Bereiter-Hahn, Wittig, Ilka, Wladislaw Kohl, Valentina Strecker, Busch, Karin, Haase, Winfried, Joos, F., Muster, Britta, Kohl, W., Strecker, Valentina, Friederike Joos, Muster, B., Bereiter-Hahn, J., Kohl, Wladislaw   +23 more
core   +2 more sources

The role of GRASP65 and GRASP55 in C-terminal valine-dependent transport to the cell surface of transmembrane proteins [PDF]

, 2008
The Golgi-matrix proteins GRASP65 and GRASP55 have recognized roles in maintaining the architecture of the Golgi complex, in mitotic progression and in unconventional protein secretion while, surprisingly, they have been shown to be dispensable for the ...
Prencipe, Libera
core   +1 more source

Proteomics analysis of mitochondrial dysfunction triggered by complex specific electron transport chain inhibitors reveals common pathways involving protein misfolding in an SH-SY5Y in vitro cell model

TURKISH JOURNAL OF BIOLOGY, 2017
Mitochondrial dysfunction has been previously identified in neurodegenerative diseases such as Alzheimer disease, Huntington disease, and Parkinson disease. Chemical inhibition of the mitochondrial electron transport chain (ETC) was shown to trigger symptoms in animal models similar to those observed in human neurodegenerative diseases.
Sahin, Betul, Baykal, Ahmet Tarik
openaire   +3 more sources

Real-Time Analysis of Mitochondrial Electron Transport Chain Function in Toxoplasma gondii Parasites Using a Seahorse XFe96 Extracellular Flux Analyzer

Bio-Protocol, 2022
The mitochondrial electron transport chain (ETC) performs several critical biological functions, including maintaining mitochondrial membrane potential, serving as an electron sink for important metabolic pathways, and contributing to the generation of ...
Jenni Hayward, Esther Rajendran, F. Makota, Brad Bassett, Michael Devoy, Teresa Neeman, Giel van Dooren   +6 more
doaj   +1 more source

Characterization of the Novel Photosynthetic Protein PPP7 involved in Cyclic Electron Flow around PSI [PDF]

, 2007
Photosynthetic organisms are able to convert light energy into chemical energy by the operation of the two photosystems, the cytochrome b6/f complex and the ATPase.
Dal Corso, Giovanni
core   +1 more source

Iron status influences mitochondrial disease progression in Complex I-deficient mice

eLife, 2023
Mitochondrial dysfunction caused by aberrant Complex I assembly and reduced activity of the electron transport chain is pathogenic in many genetic and age-related diseases.
CJ Kelly, Reid K Couch, Vivian T Ha, Camille M Bodart, Judy Wu, Sydney Huff, Nicole T Herrel, Hyunsung D Kim, Azaad O Zimmermann, Jessica Shattuck, Yu-Chen Pan, Matt Kaeberlein, Anthony S Grillo   +12 more
doaj   +1 more source

Changes in Color Stability of Beef during Postmortem Cold Storage and Underlying Mechanism [PDF]

Shipin Kexue
In order to study the color stability and change mechanism of beef during postmortem storage, quantitative proteomic analysis was carried out on bovine Longissimus dorsi with high and low color stability at 75 min, 2 days and 8 days after slaughter ...
LÜ Jintao, SHU Yimei, QUAN Wei, SHEN Qingwu
doaj   +1 more source