Results 31 to 40 of about 155,865 (232)

Elevated mitochondrial oxidative stress impairs metabolic adaptations to exercise in skeletal muscle. [PDF]

PLoS ONE, 2013
Mitochondrial oxidative stress is a complex phenomenon that is inherently tied to energy provision and is implicated in many metabolic disorders. Exercise training increases mitochondrial oxidative capacity in skeletal muscle yet it remains unclear if ...
Justin D Crane, Arkan Abadi, Bart P Hettinga, Daniel I Ogborn, Lauren G MacNeil, Gregory R Steinberg, Mark A Tarnopolsky   +6 more
doaj   +1 more source

Proteomic Analysis Suggests Altered Mitochondrial Metabolic Profile Associated With Diabetic Cardiomyopathy

Frontiers in Cardiovascular Medicine, 2022
Diabetic cardiomyopathy (DbCM) occurs independently of cardiovascular diseases or hypertension, leading to heart failure and increased risk for death in diabetic patients.
Karina P. Gomes, Karina P. Gomes, Anshul S. Jadli, Anshul S. Jadli, Luiz G. N. de Almeida, Luiz G. N. de Almeida, Noura N. Ballasy, Noura N. Ballasy, Pariya Edalat, Pariya Edalat, Ruchita Shandilya, Ruchita Shandilya, Daniel Young, Daniel Young, Darrell Belke, Darrell Belke, Jane Shearer, Jane Shearer, Antoine Dufour, Antoine Dufour, Antoine Dufour, Antoine Dufour, Vaibhav B. Patel, Vaibhav B. Patel   +23 more
doaj   +1 more source

Proteomic strategy for the analysis of the polychlorobiphenyl-degrading cyanobacterium Anabaena PD-1 exposed to Aroclor 1254.

PLoS ONE, 2014
The cyanobacterium Anabaena PD-1, which was originally isolated from polychlorobiphenyl (PCB)-contaminated paddy soils, has capabilities for dechlorinatin and for degrading the commercial PCB mixture Aroclor 1254.
Hangjun Zhang, Xiaojun Jiang, Wenfeng Xiao, Liping Lu   +3 more
doaj   +1 more source

Allergens of the urushiol family promote mitochondrial dysfunction by inhibiting the electron transport at the level of cytochromes b and chemically modify cytochrome c1

Biological Research, 2021
Background Urushiols are pro-electrophilic haptens that cause severe contact dermatitis mediated by CD8+ effector T-cells and downregulated by CD4+ T-cells.
Rodrigo Pacheco, Sergio A. Quezada, Alexis M. Kalergis, María Inés Becker, Jorge Ferreira, Alfredo E. De Ioannes   +5 more
doaj   +1 more source

Redox-Mediated Regulation of Mitochondrial Biogenesis, Dynamics, and Respiratory Chain Assembly in Yeast and Human Cells

Frontiers in Cell and Developmental Biology, 2021
Mitochondria are double-membrane organelles that contain their own genome, the mitochondrial DNA (mtDNA), and reminiscent of its endosymbiotic origin.
Stefan Geldon, Erika Fernández-Vizarra, Kostas Tokatlidis   +2 more
doaj   +1 more source

Tissue-specific mitochondrial HIGD1C promotes oxygen sensitivity in carotid body chemoreceptors

eLife, 2022
Mammalian carotid body arterial chemoreceptors function as an early warning system for hypoxia, triggering acute life-saving arousal and cardiorespiratory reflexes. To serve this role, carotid body glomus cells are highly sensitive to decreases in oxygen
Alba Timón-Gómez, Alexandra L Scharr, Nicholas Y Wong, Erwin Ni, Arijit Roy, Min Liu, Julisia Chau, Jack L Lampert, Homza Hireed, Noah S Kim, Masood Jan, Alexander R Gupta, Ryan W Day, James M Gardner, Richard JA Wilson, Antoni Barrientos, Andy J Chang   +16 more
doaj   +1 more source

Iron status influences mitochondrial disease progression in Complex I-deficient mice

eLife, 2023
Mitochondrial dysfunction caused by aberrant Complex I assembly and reduced activity of the electron transport chain is pathogenic in many genetic and age-related diseases.
CJ Kelly, Reid K Couch, Vivian T Ha, Camille M Bodart, Judy Wu, Sydney Huff, Nicole T Herrel, Hyunsung D Kim, Azaad O Zimmermann, Jessica Shattuck, Yu-Chen Pan, Matt Kaeberlein, Anthony S Grillo   +12 more
doaj   +1 more source

Proteomics analysis of mitochondrial dysfunction triggered by complex specific electron transport chain inhibitors reveals common pathways involving protein misfolding in an SH-SY5Y in vitro cell model

TURKISH JOURNAL OF BIOLOGY, 2017
Mitochondrial dysfunction has been previously identified in neurodegenerative diseases such as Alzheimer disease, Huntington disease, and Parkinson disease. Chemical inhibition of the mitochondrial electron transport chain (ETC) was shown to trigger symptoms in animal models similar to those observed in human neurodegenerative diseases.
Sahin, Betul, Baykal, Ahmet Tarik
openaire   +3 more sources

Real-Time Analysis of Mitochondrial Electron Transport Chain Function in Toxoplasma gondii Parasites Using a Seahorse XFe96 Extracellular Flux Analyzer

Bio-Protocol, 2022
The mitochondrial electron transport chain (ETC) performs several critical biological functions, including maintaining mitochondrial membrane potential, serving as an electron sink for important metabolic pathways, and contributing to the generation of ...
Jenni Hayward, Esther Rajendran, F. Makota, Brad Bassett, Michael Devoy, Teresa Neeman, Giel van Dooren   +6 more
doaj   +1 more source

Changes in Color Stability of Beef during Postmortem Cold Storage and Underlying Mechanism [PDF]

Shipin Kexue
In order to study the color stability and change mechanism of beef during postmortem storage, quantitative proteomic analysis was carried out on bovine Longissimus dorsi with high and low color stability at 75 min, 2 days and 8 days after slaughter ...
LÜ Jintao, SHU Yimei, QUAN Wei, SHEN Qingwu
doaj   +1 more source