Results 61 to 70 of about 628,628 (257)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Electron Transport Chain Complex II Regulates Steroid Metabolism
iScience, 2020 Summary: The first steroidogenic enzyme, cytochrome P450-side-chain-cleavage (SCC), requires electron transport chain (ETC) complexes III and IV to initiate steroid metabolic processes for mammalian survival.
Himangshu S. Bose +4 more
doaj
Diabetes, Metabolic Syndrome and Obesity, 2021 Ying Ben,1,2,* Juan Hao,1,* Zhihong Zhang,1,2 Yunzhao Xiong,1 Cuijuan Zhang,1,2 Yi Chang,1,2 Fan Yang,1,2 Hui Li,1,2 Tianya Zhang,1 Xiangting Wang,1,2 Qingyou Xu1,2 1Hebei University of Chinese Medicine, Shijiazhuang, Hebei, People’s Republic of ...
Ben Y +10 more
doaj
Structural study of Topoisomerase IV-DNA-Levofloxacin complexes from Streptococcus pneumoniae [PDF]
E3S Web of Conferences, 2019 S. pneumoniae is an important pathogen causing pulmonary infection, acute otitis media and purulent meningitis in infants and children. Type II topoisomerases are enzymes that play essential roles in DNA replication, chromosome segregation and ...
Wang Xilan
doaj +1 more source
Frontiers in Physiology, 2023 Introduction: Microbial pathogens undergo significant physiological changes during interactions with the infected host, including alterations in metabolism and cell architecture.
Calla L. Telzrow +6 more
doaj +1 more source
Charge transport through weakly open one dimensional quantum wires [PDF]
, 2008 We consider resonant transmission through a finite-length quantum wire connected to leads via finite transparency junctions. The coherent electron transport is strongly modified by the Coulomb interaction. The low-temperature current-voltage ($IV$) curves show step-like dependence on the bias voltage determined by the distance between the quantum ...
arxiv +1 more source
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Coupled dynamics of electrons and phonons in metallic nanotubes: current saturation from hot phonons generation [PDF]
Phys. Rev. B 73, 165419 (2006), 2006 We show that the self-consistent dynamics of both phonons and electrons is the necessary ingredient for the reliable description of the hot phonons generation during electron transport in metallic single-wall carbon nanotubes (SWNTs). We solve the coupled Boltzmann transport equations to determine in a consistent way the current vs.
arxiv +1 more source
Molecular Oncology, EarlyView.The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina +17 more
wiley +1 more source
Indications for Topological Physics in High-$T_c$ Materials [PDF]
arXiv, 2020 Research on high-$T_c$ superconductors has generally not focused on analysis of the topological structure of electronic bands in these materials. In this article we collate and discuss several well-known experimental observables that signal that certain signatures of topology may be present.
arxiv