Results 21 to 30 of about 88,401 (266)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A novel relaxation drift model for simulating liquid-vapor momentum non-equilibrium in two-phase ejectors

open access: yesCase Studies in Thermal Engineering, 2023
A novel relaxation drift model (RDM) was proposed to simulate the interphase momentum non-equilibrium (slip) inside two-phase work-recovery CO2 ejectors.
Junan Long   +5 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Design and Manufacture of a Micro-Ejector and the Testing Stand for Investigation of Micro-Ejector Refrigeration Systems

open access: yesMicromachines
This paper describes the procedure of design and manufacture of a micro-ejector proposed for miniature ejection refrigeration systems. It describes the procedure of design, fabrication, and experimentation on supersonic micro-ejectors and makes the case ...
Kamil Śmierciew   +4 more
doaj   +1 more source

A Quick Overview of Compact Air-Cooled Heat Sinks Applicable for Electronic Cooling—Recent Progress

open access: yesInventions, 2017
This study provides an overview regarding enhancement of an air-cooled heat sink applicable for electronic cooling subject to cross-flow forced convection.
Chi-Chuan Wang
doaj   +1 more source

An Experimental Study of Microchannel and Micro-Pin-Fin Based On-Chip Cooling Systems with Silicon-to-Silicon Direct Bonding

open access: yesSensors, 2020
This paper describes an experimental study of the cooling capabilities of microchannel and micro-pin-fin based on-chip cooling systems. The on-chip cooling systems integrated with a micro heat sink, simulated power IC (integrated circuit) and temperature
Yunlong Qiu   +3 more
doaj   +1 more source

Fostering Innovation: Streamlining Magnetocaloric Materials Research by Digitalization

open access: yesAdvanced Engineering Materials, EarlyView.
Magnetocaloric cooling (MCE) is an environmentally friendly refrigeration method with great potential. Optimizing MCE materials involves the preparation and screening of large quantities of samples, which in turn generates a large amount of data. A digitalization approach is presented that uses ontologies, knowledge graphs, and digital workflows to ...
Simon Bekemeier   +17 more
wiley   +1 more source

Performance Analysis of Double-Layer Microchannel Heat Sinks under Non-Uniform Heating Conditions with Random Hotspots

open access: yesMicromachines, 2017
Performance analysis of double-layer microchannel heat sinks was performed under non-uniform heating conditions having randomly distributed hotspots. Two parallel-channel (parallel-flow and counter-flow) and one cross-channel (transverse-flow) designs of
Danish Ansari, Kwang-Yong Kim
doaj   +1 more source

Heat-Dissipation Performance of Nanocomposite Phase-Change Materials in a Twin-Heat-Source System

open access: yesFluids, 2020
In this paper, pure paraffin was mixed with CuO (high thermal conductivity) and Span-80 (as a dispersant). The CuO/paraffin nanocomposite phase-change materials (PCMs) were synthesized with mass fractions of 0.3%, 0.6%, and 1.2%, by a two-step method ...
Yanxin Li   +3 more
doaj   +1 more source

The Reduction Design for Structure Borne Noise of Electronic Cabinet on Shipboard Considering Cooling Performance [PDF]

open access: yes한국정밀공학회지, 2017
An air cooling system using an axial flow fan is generally applied in an electronic cabinet on shipboard. However, cases that apply a water cooling system or a mixture of water cooling and an air cooling system are gradually increased by applying the ...
Young Min Lee   +4 more
doaj   +1 more source

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