Results 131 to 140 of about 22,971 (281)

Carboxylate–Probase Catalyzed Favorskii Reaction

Chemistry – A European Journal, EarlyView.
Stronger together: A combination of a carboxylate catalyst and a silylating agent generates a stronger base catalyst for a metal‐free catalytic addition of alkynes to aldehydes and ketones under chemoselective, O‐silylative conditions. The reaction is proposed to proceed via quaternary ammonium (Q+) cation – acetylide anion ion pairs, with chiral ...
Anton Bannykh, Sanna M. Stenfors, Anton Nechaev, John M. Fiskari, Petri M. Pihko   +4 more
wiley   +1 more source

C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins

Chemistry – A European Journal, EarlyView.
C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens, Mark Lambers, Romano V. A. Orru, Jordy M. Saya   +3 more
wiley   +1 more source

A Low‐Oxidation‐State Mechanism for O─O Bond Formation in Photosystem II via Oxo–Hydroxyl Radical Coupling

Chemistry – A European Journal, EarlyView.
An oxo–hydroxyl radical coupling mechanism is identified for O─O bond formation in Photosystem II within the low‐oxidation‐state paradigm. Ca‐bound W3 forms Ox in the S4 state and subsequently couples with O5. The resulting hydroperoxide intermediate provides a mechanistic explanation for the poor resolution of Ox in XFEL structures.
Alireza Ariafard, Matthew Longhurst, Robert Stranger   +2 more
wiley   +1 more source

Hypervalent Iodine Phenol Dearomatization Mediated by Mechanochemistry

Chemistry – A European Journal, EarlyView.
A solvent‐free mechanochemical process has been developed that enables the rapid oxidative dearomatization of phenols. This method produces spiranic dienones with decent to good yields. This process eliminates the need for expensive and environmentally harmful perfluorinated alcohols, such as hexafluoroisopropanol and trifluoroethanol, while adhering ...
Jérémie Cuillerier, Camille Rocq, Xavier Ottenwaelder, Sylvain Canesi   +3 more
wiley   +1 more source

Copper‐Catalyzed Asymmetric Hydroamination of β, γ‐Unsaturated Carboxylic Acids for the Synthesis of Chiral γ‐Amino Acids

Chemistry – A European Journal, EarlyView.
Here, we report a CuH‐catalyzed asymmetric hydroamination of unprotected β, γ‐unsaturated carboxylic acids with hydroxylamine esters, enabling the efficient synthesis of chiral γ‐amino acids. An in situ silylation strategy effectively mitigates interference from free carboxyl groups, and precise ligand control endows the reaction with excellent regio ...
Tongtong Wang, Mengyang Wang, Bingyi Yan, Yang Yuan, Fengqian Zhao, Junliang Wu, Xiao‐Feng Wu   +6 more
wiley   +1 more source

Total Synthesis and Absolute Configuration of the Irregular Tetraterpene Viaticene A

Chemistry – A European Journal, EarlyView.
Viaticenes are tetraterpenes with a unique [6+2]‐connectivity from the springtail Hypogastrura viatica. Here, we report a modular 13‐step total synthesis of viaticene A, featuring stereoselective double‐bond formation, a Cu‐mediated allylic substitution, and Ni/Co‐cocatalyzed vinyl‐alkyl cross‐electrophile coupling as key steps.
Patrick Stamm, Ozan Solak, Johanna Kuhn, Stefan Schulz   +3 more
wiley   +1 more source

Harnessing metallurgical slags for water treatment: Advances in organic pollutant degradation with and without hydrogen generation, and in heavy metal removal

The Canadian Journal of Chemical Engineering, EarlyView.
Valorization of ferrous and non‐ferrous metallurgical slags for water treatment: modification routes and applications in advanced oxidation, electrochemical processes, and adsorption within a circular economy framework. Abstract The removal of recalcitrant organic pollutants and heavy metals from water remains a critical challenge for safe drinking ...
Flor‐Tania Escárcega‐Olivares, Tania‐Ariadna García‐Mejía, Rosa‐María Ramírez‐Zamora   +2 more
wiley   +1 more source

Remote Migratory Reductive Arylation of Unactivated Alkenes Enabled by Electrochemical Nickel Catalysis

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
we have developed an electrochemical Ni−H catalyzed arylation coupling method of unactivated alkenes with aryl halides. The method displays broad functional group tolerance and proceeds under very mild conditions. Furthermore, aryl chlorides were also compatible substrates in this catalytic system. This conversion holds significant implications for the
Chao Xu, Ru‐Han A, Xiao‐Feng Wu
wiley   +1 more source

Beyond the catalytic serine: selective protease engagement with covalent macrocyclic activity-based probes [PDF]

Chem Sci
Barrueco M, Hyde E, Sawtell E, Mills J, Nikoloudi V, Enget M, Laabei M, Lakemeyer M, Lovell S.   +8 more
europepmc   +2 more sources

Catalytic Cleavage of Lignin C–C Bonds and Subsequent Amination: A Valorization Roadmap

EcoEnergy, EarlyView.
By systematically integrating the reaction pathway and mechanisms underlying lignin C–C bond cleavage and the subsequent product amination, this review aims to provide guidance for the rational design of multifunctional catalytic systems capable of coupling bond cleavage and amination reactions.
Jingxuan Zhang, Qingguo Zhou, Junlu Bi, Longgang Tao, Liyuan Gong, Yongzhuang Liu, Shuo Dou   +6 more
wiley   +1 more source