Results 251 to 260 of about 43,957 (340)

Nickel-Catalyzed Asymmetric α-Alkenylations of Acyclic Amides that Provide Tertiary Stereocenters. [PDF]

J Am Chem Soc
Hossain A, Fu GC.
europepmc   +1 more source

Electrophilic aromatic substitution of electron-rich arenes with N -fluorobenzenesulfonimide (NFSI) as an electrophile

Lina Bai, Dewei Tu, Ping Deng, Yongjie Chen, Qiang Tang   +4 more
openalex   +2 more sources

Faculty Opinions recommendation of Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants.

, 2017
Stuart A. Lipton
openalex   +2 more sources

The Dithiirane–Thiosulfine Equilibrium Revisited—A Computational Study of Structure, Thermodynamics and Kinetics

Journal of Physical Organic Chemistry, Volume 39, Issue 6, June 2026.
The dithiirane–thiosulfine equilibrium has been revisited by means of modern computational chemistry tools to shed light on whether stable thiosulfines might be isolated. ABSTRACT Thiosulfines as reactive S‐centered 1,3‐dipoles undergoing (3 + 2)‐cycloadditions are still of interest in the chemistry of sulfur‐rich heterocycles.
Dirk Buddensiek, Thomas Behrens
wiley   +1 more source

Regioselective Synthesis of Benzylsilanols from Kobayashi‐Type Reagents via C(sp3)─H Bond Activating 1,4‐Palladium Migration

Angewandte Chemie, Volume 138, Issue 21, 18 May 2026.
A Pd‐catalyzed regioselective synthesis of benzylsilanols from Kobayashi‐type reagents has been developed through a mechanistically distinct approach involving 1,4‐Pd migration followed by intramolecular transmetalation. The reaction can be combined with various prior transition‐metal‐catalyzed processes and the resulting benzylsilanols have been ...
Ryo Shintani, Keisuke Tachibana
wiley   +2 more sources

Extracting Mechanistic Information from an Open Data Set for a Pharma-Relevant Suzuki-Miyaura Cross-Coupling Reaction. [PDF]

Org Process Res Dev
Franklin BA, Donaldson NWB, Firth JD, Horbaczewskyj CS, Aspell A, Tanner T, Whitwood AC, Wilson J, Hargreaves JK, Fairlamb IJS.   +9 more
europepmc   +1 more source

Expanding the Scope of Electrophiles Capable of Targeting K-Ras Oncogenes

, 2017
Lynn M. McGregor, Meredith L. Jenkins, Caitlin Kerwin, John E. Burke, Kevan M. Shokat   +4 more
openalex   +2 more sources

Engineering an Acyl‐CoA Ligase With Enhanced Activity Toward Synthetic CoA Alternatives

ChemBioChem, Volume 27, Issue 10, 27 May 2026.
Engineering an acyl‐CoA ligase shifts thiol specificity toward inexpensive synthetic thiols such as N‐acetylcysteamine (SNAC), enabling enzymatic generation of acyl‐SNAC starter units that support polyketide biosynthesis. Fatty acyl‐coenzyme A (CoA) thioesters are indispensable intermediates in primary metabolism and essential building blocks for ...
Jared R. Cossin, Sarah A. Taboada, Gavin J. Williams   +2 more
wiley   +1 more source

Tandem Reactivity of Metal−Carbon and Carbon−Silicon Bonds in Mononuclear α‐Silyl Organolithium or Organosodium Complexes Towards CO, CO2 and Heteroallenes

Angewandte Chemie, Volume 138, Issue 21, 18 May 2026.
Anionic α‐silyl alkyl is one of the most used organometallic building blocks and funtional groups. Traditionally, the C─Si bond in these complexes is considered as inert. In this work, we report a series of reactions between mononuclear organo‐lithium and ‐sodium complexes with CO, CO2, or heteroallenes.
Xiao Yang, Jack M. Hemingway, Wataru Kanna, Nathan Davison, Hiroki Hayashi, Louise Male, Paul G. Waddell, James A. Dawson, Erli Lu   +8 more
wiley   +2 more sources

Modular Vinyl Phosphonamidates for Cysteine-Directed Protein Targeting. [PDF]

J Am Chem Soc
Stieger CE, Völkel C, Bertelsen MB, Lisurek M, Arafiles JVV, Franke J, Crocker L, Schuppe K, Lim Y, Groneberg C, Christmann M, Sun H, Hackenberger CPR.   +12 more
europepmc   +1 more source