Cancer Science, EarlyView.Fractionated irradiation generated radioresistant F‐IRR cells with enhanced CSC properties despite slower proliferation. MSI1 was strongly upregulated and functionally promoted stemness, tumorigenicity, and radiation resistance. JNK signaling acted upstream of MSI1, while JNK inhibition suppressed these malignant traits, identifying the JNK–MSI1 axis ...
Na‐Eun Kang +5 more
wiley +1 more source
Molecular diagnosis of methicillin-resistant <i>Staphylococcus aureus</i> in backyard chickens affected with bumble foot. [PDF]
Open Vet JGhayib EB, Al-Dabbagh SYA.
europepmc +1 more source
Ecological Entomology, EarlyView.Yeasts that specialize in flower nectar play an important role in pollination ecology. Metschnikowia reukaufii and Metschnikowia koreensis were the most prevalent nectar yeasts found in our field sites. Bee pollinators exhibited different behavioural responses to nectar yeasts in field experiments. Bees visited more flowers with M.
M. Elizabeth Moore +8 more
wiley +1 more source
Dual population-level processes contribute to polyclonal ceftiofur heteroresistance in swine-derived <i>Escherichia coli</i>. [PDF]
VirulenceCui J +9 more
europepmc +1 more source
The FEBS Journal, EarlyView.Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner +8 more
wiley +1 more source
BPP Bioportide™-mediated (genetic) transformation in cyanobacteria: a rapid and simplified approach for efficient molecular translocation and genome modification. [PDF]
Front Plant SciMondal S +4 more
europepmc +1 more source
The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1
The FEBS Journal, EarlyView.ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu +2 more
wiley +1 more source
Occurrence and antimicrobial susceptibility patterns of <i>Escherichia coli</i> and <i>Salmonella</i> species in raw beef from abattoir and retailer shops in Nairobi, Kenya. [PDF]
Front MicrobiolKasiwai CC +3 more
europepmc +1 more source
The sorting nexin Snx21 promotes flotillin‐mediated endocytosis
The FEBS Journal, EarlyView.In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs +9 more
wiley +1 more source
Multifunctional antimicrobial effects of <i>Lactobacillus johnsonii</i> against A/E pathogens <i>Enteropathogenic E. coli</i> and <i>Citrobacter rodentium</i>. [PDF]
Front ImmunolVasamsetti SM +6 more
europepmc +1 more source