Characterization of <i>blaNDM-1</i> and <i>blaOXA-23</i>-Type Carbapenemases in <i>Acinetobacter baumannii</i> Isolated from Post-Surgical Patients. [PDF]
Gul S +8 more
europepmc +1 more source
Fractionated irradiation generated radioresistant F‐IRR cells with enhanced CSC properties despite slower proliferation. MSI1 was strongly upregulated and functionally promoted stemness, tumorigenicity, and radiation resistance. JNK signaling acted upstream of MSI1, while JNK inhibition suppressed these malignant traits, identifying the JNK–MSI1 axis ...
Na‐Eun Kang +5 more
wiley +1 more source
Generation of Human Bioartificial Tissues Using Agarose-Derived Biomaterials. [PDF]
Campos F +8 more
europepmc +1 more source
Yeasts that specialize in flower nectar play an important role in pollination ecology. Metschnikowia reukaufii and Metschnikowia koreensis were the most prevalent nectar yeasts found in our field sites. Bee pollinators exhibited different behavioural responses to nectar yeasts in field experiments. Bees visited more flowers with M.
M. Elizabeth Moore +8 more
wiley +1 more source
The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1
ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu +2 more
wiley +1 more source
Atypical multidrug-resistant serotype 1 <i>Actinobacillus pleuropneumoniae</i> with <i>ApxIII</i> in China. [PDF]
Duan C +12 more
europepmc +1 more source
The sorting nexin Snx21 promotes flotillin‐mediated endocytosis
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs +9 more
wiley +1 more source
The transcriptional regulator CueR positively regulates the expression of the <i>cueRA</i> operon to maintain copper homeostasis in <i>Pseudomonas chlororaphis</i> zm-1. [PDF]
Wang Z +6 more
europepmc +1 more source
Blocking protein quality control degradation by deleting the E3 ligases Ubr1 or San1 stabilizes many DHFR insertion and deletion variants that are otherwise partially unfolded. These hypomorphic variants regain folding at lower temperatures or upon methotrexate binding, revealing that PQC degradation can remove proteins that are still functionally ...
Sven Larsen‐Ledet +6 more
wiley +1 more source
Carriage and susceptibility of Enterobacteria isolated from the local chickens at markets and peri-urban areas of Bobo-Dioulasso, Burkina Faso. [PDF]
Zon D +10 more
europepmc +1 more source

