Results 91 to 100 of about 226,631 (305)

HiTRACE: High-throughput robust analysis for capillary electrophoresis [PDF]

, 2011
Motivation: Capillary electrophoresis (CE) of nucleic acids is a workhorse technology underlying high-throughput genome analysis and large-scale chemical mapping for nucleic acid structural inference. Despite the wide availability of CE-based instruments,
Bylund, Cormen, Cover, Das, Das, Deigan, Ewing, Ewing, Hanjoo Kim, Jinkyu Kim, Justine Hum, Kay, Kazmi, Kladwang, Kladwang, Laederach, Levenberg, Marquardt, Merino, Mitra, Nielsen, Oppenheim, Peattie, Pravdova, Rhiju Das, Robinson, Ruiz-Martinez, Seunghyun Park, Sungroh Yoon, Tijerina, Tomasi, Vasa, Walczak, Watts, Weeks, Wilkinson, Wipapat Kladwang, Wong, Woolley, Xi   +39 more
core   +1 more source

Capillary electrophoresis of biomolecules [PDF]

Analytical and Bioanalytical Chemistry, 2015
The introduction of modern capillary electrophoresis to separation science has dramatically changed the nature of bioanalytical research. Selectivity based on charge-to-size ratio can be expandedwith the addition of secondary selectors to the background electrolyte.
openaire   +2 more sources

Cancer Immunotherapy via Disruption of Integrin αvβ3 and CD47 Costabilization on Cancer Cell Surface

Advanced Science, EarlyView.
This study identifies a cancer‐specific interaction between CD47 and integrin αvβ3 that facilitates immune evasion. A rationally designed peptide, PSFL‐NK13, disrupts this axis, enhancing macrophage‐mediated phagocytosis and suppressing tumor growth without inducing anemia.
Peng‐Cheng Yu, Chen‐Xi Yue, Wen‐Zhong Dong, Cui‐Yun Hao, Yi‐Fan Qiao, Di Liu, Xin Zhang, Qi Zhan, Jia‐Bao Yao, Dong‐Ping Wang, Peng Cao, Ying‐Zhe Fan, Ye Yu   +12 more
wiley   +1 more source

Applications of capillary electrophoresis to the analysis of compounds of clinical, forensic, cosmetological, environmental, nutritional and pharmaceutical importance

Journal of the Brazilian Chemical Society, 2003
Since its inception in the 80's, capillary electrophoresis has matured into a well-established separation technique, actually encompassing a family of electrodriven techniques with distinct separation mechanisms and selectivity, performed in a single ...
Tavares Marina F. M., Jager Alessandra V., Silva Clóvis L. da, Moraes Edgar P., Pereira Elisabete A., Lima Elizabete C. de, Fonseca Fabiana N., Tonin Fernando G., Micke Gustavo A., Santos Márcia R., Oliveira Marcone A. L. de, Moraes Maria de Lourdes L. de, Kampen Maria Helena van, Fujiya Neide M.   +13 more
doaj  

Statistical modeling of STR capillary electrophoresis signal

BMC Bioinformatics, 2019
Background In order to isolate an individual’s genotype from a sample of biological material, most laboratories use PCR and Capillary Electrophoresis (CE) to construct a genetic profile based on polymorphic loci known as Short Tandem Repeats (STRs).
Slim Karkar, Lauren E. Alfonse, Catherine M. Grgicak, Desmond S. Lun   +3 more
doaj   +1 more source

Microfluidic method for rapid turbidimetric detection of the DNA of Mycobacterium tuberculosis using loop-mediated isothermal amplification in capillary tubes [PDF]

, 2015
We describe a microfluidic method for rapid isothermal turbidimetric detection of the DNA of Mycobacterium tuberculosis. Loop-mediated isothermal amplification is accomplished in capillary tubes for amplifying DNA in less than 15 min, and sensitivity and
Gill, P., Rafati, A.
core  

Phagocytic properties of lung alveolar wall cells [PDF]

, 1974
For the purpose to define the mechanism of heavy metal intoxication by inhalation, morphologic observations were made on rat lungs after nasal instillation of iron colloid particles of positive and negative electric charges. Histochemical observation was
Tanaka, Akisuke
core   +1 more source

Stimuli‐Responsive CuFeTe2 Nanosheets for Amplified Cuproptosis/Ferroptosis in Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Dual‐stimuli‐responsive CuFeTe2 nanosheets (CFT) induce cuproptosis/ferroptosis via TME‐responsive Fe2⁺/Cu2⁺ release and NIR‐II photothermal effects, amplifying ROS and depleting HSP70/ATP to trigger ICD and immune activation, while ensuring biocompatible renal clearance for TNBC therapy.
Molin Liu, Jian Zheng, Mengqi Yu, Qirui Wang, Yi Yuan, Nannan Shao, Xiaoliang Yang, Tianxi Shen, Li Wang, Aiyun Li, Rui Liu, Jimin Cao, Xi Liu, Fangfang Cao, Yanlin Feng   +14 more
wiley   +1 more source

New analytical challenges in characterization of antibody-drug conjugates

Journal of Chromatography Open
Since 1913, when Paul Ehrlich introduced the concept of “selective toxicity”, new strategies to obtain quality control, quantification of the drug were mandatory. For this reason, the introduction of antibody drug conjugates (ADC) has shown many critical
Erika Maria Ricci, Enrico Dainese, Vincenzo De Laurenzi, Giulio Lovato, Gianluca Sala, Marcello Locatelli, Miryam Perrucci   +6 more
doaj   +1 more source

Optical sensing in microchip capillary electrophoresis by femtosecond laser written waveguides [PDF]

, 2009
Capillary electrophoresis separation in an on-chip integrated microfluidic channel is typically monitored with bulky, bench-top optical excitation/detection instrumentation.
Cerullo, G., Chiari, M., Cretich, M., Dongre, C., Hoekstra, H.J.W.M., Martinez-Vázquez, R., Osellame, R., Pollnau, M., Ramponi, R., Vlekkert, H. van den   +9 more
core   +1 more source