Results 141 to 150 of about 205,159 (276)

A Computational Resolution of the Inverse Problem of Kinetic Capillary Electrophoresis (KCE) [PDF]

arXiv, 2017
Determining kinetic rate constants is a highly relevant problem in biochemistry, so various methods have been designed to extract them from experimental data. Such methods have two main components: the experimental apparatus and the subsequent analysis, the latter often dependent on mathematical theory.
arxiv  

Therapeutic Potential of Lipid Nanoparticle‐Encapsulated CD19‐Targeting mRNAs in Lupus and Rheumatoid Arthritis

Advanced Science, EarlyView.
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo, Yingsen Tang, Ling Zeng, Xiaomei You, Siweier Luo, Yufei Du, Le Wang, Liangchun Wang, Jianchuan Wang, Jinjin Chen, Yiming Zhou   +10 more
wiley   +1 more source

Advanced Analytical Methods for Pharmaceutical and Diagnostic Applications

CHIMIA, 1997
Driving forces for the development of novel analytical technologies in the life-science industry are described. Technologies which either were developed in Bio-Analytical Research or brought to a reliability required for routine applications ...
Markus Ehrat, Gert L. Duveneck, Gerhard M. Kresbach, Peter Oroszlan, Aran Paulus   +4 more
doaj   +2 more sources

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

Determination of creatinine and creatine by capillary electrophoresis : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University [PDF]

, 1998
The assessment of creatinine and creatine in biological fluids is important in the evaluation of renal and muscular functions. For routine creatinine determinations in the clinical laboratory, the most frequently used method is the spectrophotometric one
Guo, Hong
core  

Capillary electrophoresis fragment analysis and clone sequencing in detection of dynamic mutations of spinocerebellar ataxia

Chinese Journal of Contemporary Neurology and Neurosurgery, 2018
Objective To estimate the accuracy and stability of capillary electrophoresis fragment analysis and clone sequencing in detecting dynamic mutations of spinocerebellar ataxia (SCA). Methods Capillary electrophoresis fragment analysis and clone sequencing
Yuan-yuan CHEN, Ying HAO, Jin ZHANG, Xin ZHANG, Kun-ming XIE, Ming DING, Wei-hong GU   +6 more
doaj  

Enabling High‐Voltage Polymer‐Based Solid‐State Batteries Through Reinforcements with LiAlO2 Fillers

Advanced Energy Materials, EarlyView.
Polymer‐ceramic solid composite electrolytes with passive LiAlO2 fillers show remarkable improvements in Li‐ion conductivity in polycarbonates as compared to both non‐conductive Al2O3 and conductive Li7La3Zr2O12 counterparts. The exceptionally high transference numbers contribute to reversible and stable electrochemistry with Li‐metal electrodes and to
Kenza Elbouazzaoui, Andrii Mahun, Valeriia Shabikova, Laurent Rubatat, Kristina Edström, Jonas Mindemark, Daniel Brandell   +6 more
wiley   +1 more source

Separation of Chlorins and Carotenoids in Capillary Electrophoresis [PDF]

, 2017
The present study reports the investigation of capillary electrophoresis (CE) for the separation of the photosynthetic pigments (chlorophyll derivatives as well as carotenoids) together. Various CE methods, such as micellar electrokinetic chromatography,
Belin, Gamze Kavran, Gülaçar, Fazil O.
core  

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

Advanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu, Amar Salehi, Lei Xu, Wei Yuan, Tingting Yu   +4 more
wiley   +1 more source

Establishment of rat model for aspiration pneumonia and potential mechanisms

Animal Models and Experimental Medicine, EarlyView.
Aspiration pneumonia was induced in Sprague Dawley rats by intratracheal instillation of hydrochloric acid (HCl, 1.5 μL/g.wt, pH = 1) followed by lipopolysaccharide (LPS, 20 μg/g.wt) after 1 h. The model reproduced hallmark features of acute lung injury, including histological lung damage, microvascular dysfunction, inflammation, hypoxemia, and ...
Hanbing Hu, Junfeng Chen, Yiru Shao, Yuedong Tang, Yu Dun, Obulkasim Memet, Xuanrong Bao, Jie Shen   +7 more
wiley   +1 more source