Results 211 to 220 of about 205,159 (276)

Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
wiley   +1 more source

A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT The ICH Q14 guideline introduces a structured framework for analytical method development based on Analytical Quality by Design (AQbD) principles, aiming to ensure robust, reliable, and fit‐for‐purpose methods throughout the product lifecycle.
Ewoud van Tricht   +1 more
wiley   +1 more source

A Comprehensive Evaluation of Analytical Method Parameters Critical to the Reliable Assessment of Therapeutic mRNA Integrity by Capillary Gel Electrophoresis

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT In recent years, messenger ribonucleic acid (mRNA)‐lipid nanoparticle (LNP) biotherapeutics have demonstrated significant promise in disease treatment and prevention given their rapidly modifiable production processes and considerable capacity to adapt to complex or low‐yielding proteins of interest.
Jessica P. Tran   +7 more
wiley   +1 more source

Enabling icIEF Peak Identification of AAV Capsid Proteins by Fractionation on MauriceFlex and Subsequent Analysis by LC-MS. [PDF]

open access: yesElectrophoresis
McElroy W   +8 more
europepmc   +1 more source

A SNaPshot Assay for Epigenetic Age Prediction of Costal Cartilage

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT Estimating age at death narrows the pool of potential donors in mass disasters and criminal investigations. In this study, we developed a capillary electrophoresis‐based SNaPshot assay for age prediction of costal cartilage and used it to analyze DNA methylation at 11 CpG sites across six genes in 136 samples from deceased Koreans aged 28–84 ...
Ju Yeon Jung   +5 more
wiley   +1 more source

Characterization of Taurocholic Acid Binding With Insulin for Potential Oral Formulation Using Different Methods

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT In diabetes management, oral formulation of insulin (INS) has the potential to improve safety, convenience, and patient‐centered care compared to subcutaneous injections. However, its bioavailability remains limited, necessitating improved delivery strategies.
Chang Sun   +3 more
wiley   +1 more source

A capillary electrophoresis-based assay for carrier screening of the hotspot mutations in the CYP21A2 gene. [PDF]

open access: yesHeliyon
Tan J   +10 more
europepmc   +1 more source

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