Results 51 to 60 of about 115,772 (271)

Targeted Long‐Read Sequencing as a Single Assay Improves the Diagnosis of Spastic‐Ataxia Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The hereditary spastic‐ataxia spectrum disorders are a group of disabling neurological diseases. The traditional genetic testing pathway is complex, multistep and leaves many cases unsolved. We aim to streamline and improve this process using long‐read sequencing. Methods We developed a targeted long‐read sequencing strategy with the
Laura Ivete Rudaks, Igor Stevanovski, Dennis Yeow, Andre L. M. Reis, Sanjog R. Chintalaphani, Pak Leng Cheong, Hasindu Gamaarachchi, Lisa Worgan, Kate Ahmad, Michael Hayes, Andrew Hannaford, Samuel Kim, Victor S. C. Fung, Gabor M. Halmagyi, Andrew Martin, David Manser, Michel Tchan, Karl Ng, Marina L. Kennerson, Ira W. Deveson, Kishore Raj Kumar   +20 more
wiley   +1 more source

Spider Silk: Rapid, Bottom‐Up Self‐Assembly of MaSp1 into Hierarchically Structured Fibers Through Biomimetic Processing

Advanced Functional Materials, EarlyView.
Spider dragline silk has extraordinary mechanical properties due to the underlying hierarchical organization of the fiber across multiple length scales. A biomimetic platform for MaSp1 is developed, the main protein component of dragline silk, and thereby elucidates the parameters governing its rapid self‐assembly from soluble protein into complex ...
Ali D. Malay, Nur Alia Oktaviani, Jianming Chen, Keiji Numata   +3 more
wiley   +1 more source

Adsorption of colloidal particles in the presence of external field [PDF]

, 1995
We present a new class of sequential adsorption models in which the adsorbing particles reach the surface following an inclined direction (shadow models). Capillary electrophoresis, adsorption in the presence of a shear or on an inclined substrate are physical manifestations of these models.
arxiv   +1 more source

Development and application of post-capillary affinity detection for capillary electrophoresis [PDF]

, 1997
Protein variants can arise from transcription errors, post-translational modifications, as well as chemical or proteolytic degradation. In this work post-capillary affinity detection for capillary electrophoresis is developed to assess protein ...
Kelly, Jean Abler
core   +3 more sources

Sustainable Spinning of Artificial Spider Silk Fibers with Excellent Toughness and Inherent Potential for Functionalization

Advanced Functional Materials, EarlyView.
A sustainable aqueous wet spinning method enables an efficient production of artificial spider silk fibers which show excellent extensibility and remarkable toughness. A highly specific and efficient biomolecular click reaction is employed to functionalize these fibers under mild conditions, which offers a promising method to construct multi‐functional
Ruxia Fan, Katarina Knuuttila, Benjamin Schmuck, Gabriele Greco, Anna Rising, Markus B. Linder, A. Sesilja Aranko   +6 more
wiley   +1 more source

Portable capillary-based (non-chip) capillary electrophoresis [PDF]

, 2010
Miniaturized, portable instrumentation has been gaining popularity in all areas of analytical chemistry. Capillary electrophoresis (CE), due to its main strengths of high separation efficiency, relatively short analysis time and low consumption of ...
Brabazon, Dermot, Macka, Mirek, Preisler, Jan, Ryvolova, Marketa   +3 more
core   +1 more source

Holistic Analysis of Material Properties in Phylogenetically Diverse Spider Silks and Their Influence on Cell Adhesion

Advanced Functional Materials, EarlyView.
Translation of recombinant spider silks as fillers for nerve guidance conduits in long‐segment nerve reconstruction demands a detailed examination of native counterparts. Thus, this study conducts a comprehensive analysis of the material properties of four phylogenetically diverse spider silks and their impact on Schwann cell adhesion, pinpointing key ...
Sarah Stadlmayr, Andreas Mautner, Markus Bacher, Karolina Peter, Axel Mentler, Stefan Schulz, Helga Lichtenegger, Lothar Brecker, Alexander Bismarck, Aida Naghilou, Christine Radtke   +10 more
wiley   +1 more source

Recent advances in screening of enzymes inhibitors based on capillary electrophoresis

Journal of Pharmaceutical Analysis, 2018
Capillary electrophoresis with many advantages plays an important role in pharmaceutical analysis and drug screening. This review gives an overview on the recent advances in the developments and applications of capillary electrophoresis in the field of ...
Mengxia Cheng, Zilin Chen
doaj  

Kapilarna elektroforeza u farmaciji [PDF]

, 2010
Capillary electrophoresis is a new separation technique. It is an analytical technique that usually complements or replaces high performance liquid chromatography.
Damić, Miranda, Nigović, Biljana
core   +1 more source

Method Design for Separation of Non-Canonical DNA Structures via Capillary Electrophoresis [PDF]

, 2023
G-quadruplex DNA structures are highly relevant subjects of biochemical study, implicated in human diseases and cancer. Conventional methods for G-quadruplex DNA structure separation are time-consuming, environmentally unfriendly, and low throughput ...
Chen, Erin V., , \u2723
core   +1 more source