Results 161 to 170 of about 210,369 (310)

Dried blood spot sample extraction for metabolomics and proteomics profiling for clinical trials: a descriptive exploratory study. [PDF]

Sci Rep
Fägerstam S, Johansson E, Af Geijerstam P, Rådholm K, Ghafouri B.   +4 more
europepmc   +1 more source

Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis

Advanced Science, EarlyView.
Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang, Linlin Xu, Chenglong Pan, Ruonan Cao, Piao Zeng, Xinxing Lyu, Qingxia Hu, Zhenzhen Yan, Shuhong Huang, Ningning Dang   +9 more
wiley   +1 more source

An efficient clear-native PAGE-based workflow for cryo-electron microscopy sample preparation of large protein complexes. [PDF]

Plant Methods
Yang Z, Kameo S, Seki S, Kurisu G, Tanaka R, Kawamoto A, Takabayashi A.   +6 more
europepmc   +1 more source

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

Advanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang, Bin Li, Zhijin Fan, Yan Yan, Fei Ma, Changting He, Shiping Liu, Mingliang Pan, Zhou Pan, Huijuan Wang, Xinting Fu, Jiamei Wang, Yue Jia, Qin Gu, Duo Jiang, Xueting Liu, Bohua Ren, Qinqin Wang, Yuehua Hei, Han Duan, Yanqiu Wu, Zihui Wei, Liying Zhan, Yuhui Liao   +23 more
wiley   +1 more source

Early proteomic signatures of impaired maxillary bone remodeling under mechanical stress in type 1 diabetes mellitus. [PDF]

J Oral Biol Craniofac Res
Tobias-López LF, Trejo-Iriarte CG, García-Muñoz A, Gómez-Clavel JF.   +3 more
europepmc   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Proteomic analysis of proteins responsive to drought stress in barley. [PDF]

BMC Plant Biol
Ramadan WA, Mahmoud FE, Abou-Deif MH, Ali M.   +3 more
europepmc   +1 more source

Constraint of Lignin–Carbohydrate Complex Orchestrated on Polyphenol in Oil–Water Interface Targeting Ulcerative Colitis Therapy

Advanced Science, EarlyView.
This study constructed the W1/O/W2 emulsion–based targeted therapy delivery system for ulcerative colitis (UC) utilizing LCC as surfactant for the first time. This multifunctional emulsion offered certain therapeutic advantages for UC, including targeted colonic delivery of active compounds, synergistic modulation of gut microbiota through combined ...
Qian Wu, Xingyu Zhang, Jingjia Zhang, Gaohui Huang, Chen Zhou, Chunlin Li, Xiaojun Huang, Jianbo Xiao, Nianjie Feng, Yuanbin She   +9 more
wiley   +1 more source

Supramolecular Biopolymer Composed of a Doubly (His)₆-Tagged Tandem Z-Domain Conjugated by Zn^2<b>+</b> Ions. [PDF]

ACS Synth Biol
Razi SG, Krichevsky O, Wachtel E, Albeck S, Peleg Y, Patchornik G.   +5 more
europepmc   +1 more source

Tackling the challenge of quantifying co-migrating proteins in two dimensional gel electrophoresis-based proteome analysis [PDF]

, 2007
Deforce, Dieter, Dhaenens, Maarten, Vandecasteele, Sofie   +2 more
core   +1 more source