Results 41 to 50 of about 1,791,968 (388)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Ultrasound applied at low temperature on the extraction and modification of proteins from by-products of the fishing industry [PDF]

Ciência Rural
: This study explored the use only of ultrasound (US) for extracting proteins from grass carp (Ctenopharyngodon idella) backbones at low temperature and examined its impact on hydrophobicity, solubility, electrophoretic profile, and sulfhydryl levels ...
Silvino Sasso Robalo, Gregorio Cargnin, Leila Picolli da Silva, Paulo Cezar Bastianello Campagnol, Roger Wagner, Juliano Smanioto Barin, Carla Cristina Bauermann Brasil, Cristiano Ragagnin de Menezes, Alexandre José Cichoski   +8 more
doaj   +1 more source

Band-collision gel electrophoresis. [PDF]

, 2019
Electrophoretic mobility shift assays are widely used in gel electrophoresis to study binding interactions between different molecular species loaded into the same well.
Bikos, Dimitri A, Mason, Thomas G
core  

Mesoscale modelling of polyelectrolyte electrophoresis

, 2009
The electrophoretic behaviour of flexible polyelectrolyte chains ranging from single monomers up to long fragments of hundred repeat units is studied by a mesoscopic simulation approach.
Ahlrichs, Antypov, Antypov, Barrat, Belloni, Belloni, Christian Holm, Cottet, Cottet, Deserno, Deserno, Dolnik, Grass, Grass, Grass, Hoagland, Kai Grass, Limbach, Limbach, Lobaskin, Long, Manning, McNamara, Mohanty, Moore, Muthukumar, Oosawa, Slater, Soddemann, Tanaka, Volkel, Weeks, Wette, Wolff   +33 more
core   +2 more sources

Identification of Structural Proteins of Rhizobium meliloti Temperate Phage 16-3 [PDF]

, 1982
The structural proteins of Rhizobium meliloti temperate phage 16-3 have been analysed by means of polyacrylamide gel electrophoresis, isoelectric focusing and agarose gel electrophoresis.
Duda, Ernő, Dudás, Brigitta, Erdei, Sára, Orosz, László   +3 more
core   +1 more source

Recent advances in capillary electrophoresis‐mass spectrometry: Instrumentation, methodology and applications

Electrophoresis, 2018
Capillary electrophoresis (CE) offers fast and high‐resolution separation of charged analytes from small injection volumes. Coupled to mass spectrometry (MS), it represents a powerful analytical technique providing (exact) mass information and enables ...
Alexander Stolz, Kevin Jooss, Oliver Höcker, Jennifer Römer, Johannes Schlecht, C. Neusüß   +5 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The effect of antimicrobial agents on planktonic and biofilm forms of bacteria that are isolated from chronic anal fissures

Regulatory Mechanisms in Biosystems, 2017
The microorganisms that are formed in biofilm cause about 60% of chronic and recurrent diseases, and as a consequence, traditional etiotropic antibacterial therapy is ineffective.
I. M. Kozlovska, N. Y. Romanjuk, L. M. Romanjuk, M. D. Kukhtyn, Y. V. Horiuk, G. V. Karpyk   +5 more
doaj   +1 more source

Agarose Gel Electrophoresis.

Cold Spring Harbor Protocols, 2019
This protocol describes steps for the preparation and running of agarose gels and for staining and visualization of DNA in gels using three dyes: ethidium bromide, SYBR Gold, and SYBR Green 1.
Michael R Green, J. Sambrook
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source