Results 11 to 20 of about 68,565 (138)

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Combined effect of neolamarckia cadamba leaves and electroporation method on hela cell anti- proliferation process [PDF]

open access: yes, 2019
This study suggests that natural sources may become an important tool in treating cancer. Neolamarckia cadamba (NC) leaves also well-known as “Anthocephalus Cadamba”, is a precious plant in Ayurvedic medicine.
Abd Rahman, Nur Adilah   +6 more
core   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

A Study on Nonthermal Irreversible Electroporation of the Thyroid. [PDF]

open access: yes, 2019
BackgroundNonthermal irreversible electroporation is a minimally invasive surgery technology that employs high and brief electric fields to ablate undesirable tissues.
Huang, Jianwei   +4 more
core  

Enhancement of electroporation facilitated immunogene therapy via T-reg depletion [PDF]

open access: yes, 2014
Regulatory T cells (T-regs) can negatively impact tumor antigen-specific immune responses after infiltration into tumor tissue. However, depletion of T-regs can facilitate enhanced anti-tumor responses, thus augmenting the potential for immunotherapies ...
A Testori   +28 more
core   +1 more source

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee   +6 more
wiley   +1 more source

Single cell electroporation on chip [PDF]

open access: yes, 2006
In this thesis the results of the development of microfluidic cell trap devices for single cell electroporation are described, which are to be used for gene transfection.
Valero, Ana
core   +2 more sources

Prostate cancer treatment with Irreversible Electroporation (IRE): Safety, efficacy and clinical experience in 471 treatments. [PDF]

open access: yes, 2019
BackgroundIrreversible Electroporation (IRE) is a novel image-guided tissue ablation technology that induces cell death via very short but strong pulsed electric fields.
Guenther, E   +6 more
core   +2 more sources

Biofilm Control by Active Topography with Mucin Coating

open access: yesAdvanced Functional Materials, EarlyView.
This study reports a new antifouling strategy based on a bioinspired design. Mucin coating enhances biofilm control by active topography with beating micron‐sized pillars. Besides the mechanical force of beating pillars, the antibiofilm activities also involve biological factors since mucin coating inhibits swarming motility and c‐di‐GMP synthesis in ...
Zehui Han   +4 more
wiley   +1 more source

Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma. [PDF]

open access: yes, 2020
PurposeTumors with low frequencies of checkpoint positive tumor-infiltrating lymphocytes (cpTIL) have a low likelihood of response to PD-1 blockade.
Algazi, Alain P   +23 more
core   +2 more sources

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