Results 31 to 40 of about 135,255 (300)

Electroporation in Microfluidic Devices [PDF]

open access: yes, 2016
Crossing the plasma cellular membrane for loading of exogenous substances or accessing the intracellular medium is essential for cell engineering and transfection, cell analysis, or controlled extraction of the cellular content. Various chemical and physical techniques have been developed to open up the cell membrane and allow molecular exchange ...
Le Gac, Séverine, van Uitert, Iris
openaire   +3 more sources

Irreversible Electroporation [PDF]

open access: yesSeminars in Interventional Radiology, 2015
Irreversible electroporation (IRE) is a predominantly nonthermal ablative technology that uses high-voltage, low-energy DC current pulses to induce cell death. Thermal ablative technologies such as radiofrequency ablation, microwave ablation, and cryoablation have several applications in oncology but have limitations that have been established. IRE has
openaire   +2 more sources

Irreversible electroporation: evolution of a laboratory technique in interventional oncology [PDF]

open access: yes, 2014
Electroporation involves applying electric field pulses to cells, leading to the alteration or destruction of cell membranes. Irreversible electroporation (IRE) creates permanent defects in cell membranes and induces cell death. By directly targeting IRE
Ronald S. Arellano,   +4 more
core   +1 more source

Irreversible electroporation combined with immunotherapy versus irreversible electroporation alone for locally advanced pancreatic cancer: a systematic review and meta-analysis [PDF]

open access: yesEinstein (São Paulo)
Objective: The aim of this meta-analysis was to determine the efficacy and safety of percutaneous irreversible electroporation combined with immunotherapy compared with irreversible electroporation alone in patients with locally advanced pancreatic ...
Miriana Mariussi   +11 more
doaj   +2 more sources

Pulse Duration Dependent Asymmetry in Molecular Transmembrane Transport Due to Electroporation in H9c2 Rat Cardiac Myoblast Cells In Vitro

open access: yesMolecules, 2021
Electroporation (EP) is one of the successful physical methods for intracellular drug delivery, which temporarily permeabilizes plasma membrane by exposing cells to electric pulses.
Tina Batista Napotnik   +1 more
doaj   +1 more source

Electroporation of cell membranes [PDF]

open access: yesBiophysical Journal, 1989
Electric pulses of intensity in kilovolts per centimeter and of duration in microseconds to milliseconds cause a temporary loss of the semipermeability of cell membranes, thus leading to ion leakage, escape of metabolites, and increased uptake by cells of drugs, molecular probes, and DNA.
openaire   +2 more sources

The Effect of Conductivity Changes on Temperature Rise During Irreversible Electroporation

open access: yesFrontiers in Biomedical Technologies, 2020
Purpose: Irreversible electroporation is a physical process which is used for killing the cancer cells. The process that leads to cell death in this method is a unique process. Thermal damage does not exist in this process.
Amir Khorasani
doaj   +1 more source

Interrogation on the Cellular Nano-Interface and Biosafety of Repeated Nano-Electroporation by Nanostraw System

open access: yesBiosensors, 2022
Cell perforation is a critical step for intracellular drug delivery and real-time biosensing of intracellular signals. In recent years, the nanostraws system has been developed to achieve intracellular drug delivery with minimal invasiveness to the cells.
Aihua Zhang   +5 more
doaj   +1 more source

A statistical model describing combined irreversible electroporation and electroporation-induced blood-brain barrier disruption

open access: yesRadiology and Oncology, 2016
Electroporation-based therapies such as electrochemotherapy (ECT) and irreversible electroporation (IRE) are emerging as promising tools for treatment of tumors.
Sharabi Shirley   +7 more
doaj   +1 more source

Cell death due to electroporation

open access: yes, 2021
Exposure of cells to high voltage electric pulses increases transiently membrane permeability through membrane electroporation. Electroporation can be reversible and is used in gene transfer and enhanced drug delivery but can also lead to cell death ...
Miklavčič, Damijan   +5 more
core   +1 more source

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