Results 41 to 50 of about 133,618 (201)
Non-viral delivery and optimized optogenetic stimulation of retinal ganglion cells led to behavioral restoration of vision [PDF]
, 2012 Stimulation of retinal neurons using optogenetics via use of chanelrhodopsin-2 (ChR2) has opened up a new direction for restoration of vision for treatment of retinitis pigmentosa (RP).
Shivaranjani Shivalingaiah +4 more
core +1 more source
Calcium Electroporation: Evidence for Differential Effects in Normal and Malignant Cell Lines, Evaluated in a 3D Spheroid Model. [PDF]
PLoS ONE, 2015 Calcium electroporation describes the use of high voltage electric pulses to introduce supraphysiological calcium concentrations into cells. This promising method is currently in clinical trial as an anti-cancer treatment. One very important issue is the
Stine Krog Frandsen +4 more
doaj +1 more source
Long-term in vivo gene expression in mouse kidney using φC31 integrase and electroporation [PDF]
, 2015 Background: Achieving long-term gene expression in kidney will be beneficial for gene therapy of renal and congenital diseases, genetic studies constructing animal disease models, and the functional analysis of disease-related genes. Purpose: The purpose
Yamashita, Fumiyoshi +5 more
core +1 more source
The effects of electroporation on viability and quality of in vivo-derived bovine blastocysts
The Journal of Reproduction and Development, 2019 The introduction of exogenous molecules into embryos is required for analyses of molecular dynamics and specific gene functions during early embryonic development. Electroporation is an effective method to transport exogenous molecules into cells, but is
Fuminori TANIHARA +8 more
doaj +1 more source
Journal of Experimental Life Science, 2017 Successful studies about implementation of electroporation method which sperm becomes gene transfer medium for fish transgenesis have reported. Motility and viability are two major factors in successful of electroporation.
Diana Aisyah +2 more
doaj +1 more source
A protocol for in ovo electroporation of chicken and snake embryos to study forebrain development
STAR Protocols, 2021 Summary: In vivo electroporation has become a key technique to study genetic mechanisms of brain development. However, electroporation of the embryonic pallium in oviparous species, interesting for evolutionary studies but distinct from in utero ...
Adrián Cárdenas, Víctor Borrell
doaj +1 more source
Design and Construction of a Programmable Electroporation system for Biological Applications
, 2007 Studies into electroporation have grown rapidly in biotechnology and medicine in recent years. This paper presents the design and construction of a low cost programmable electroporation system for biological applications. The system consists of a control
Beeby, Steve +4 more
core +1 more source
Urology Research and Practice, 2023 Objective: This article reports on the early results of a 1-year follow-up study investigating the efficacy of irreversible electroporation in the treatment of localized prostate cancer. Methods: The study included 18 out of 40 patients diagnosed with
Şükrü Ali Altan +3 more
doaj +1 more source
, 2022 Molecule characterization of live single cells is greatly important in disease diagnoses and personalized treatments. Conventional molecule detection methods, such as mass spectrography, gene sequencing, or immunofluorescence, are usually destructive or ...
Shengsen Zhang (6244061) +2 more
core +1 more source
Journal of Experimental Life Science, 2016 Spermatozoa are male gametes that have an advantage in acting as gene transfer media (SMGT), because in transferring genetic material, sperm uses relatively natural vectors.
Saidah Luthfiyah +2 more
doaj +1 more source