Results 41 to 50 of about 182,543 (292)

Pulse Duration Dependent Asymmetry in Molecular Transmembrane Transport Due to Electroporation in H9c2 Rat Cardiac Myoblast Cells In Vitro

Molecules, 2021
Electroporation (EP) is one of the successful physical methods for intracellular drug delivery, which temporarily permeabilizes plasma membrane by exposing cells to electric pulses.
Tina Batista Napotnik, Damijan Miklavčič   +1 more
doaj   +1 more source

Electroporation of Mycobacteria [PDF]

Journal of Visualized Experiments, 2008
High efficiency transformation is a major limitation in the study of mycobacteria. The genus Mycobacterium can be difficult to transform; this is mainly caused by the thick and waxy cell wall, but is compounded by the fact that most molecular techniques have been developed for distantly-related species such as Escherichia coli and Bacillus subtilis. In
Renan, Goude, Tanya, Parish
openaire   +3 more sources

Irreversible electroporation combined with immunotherapy versus irreversible electroporation alone for locally advanced pancreatic cancer: a systematic review and meta-analysis [PDF]

Einstein (São Paulo)
Objective: The aim of this meta-analysis was to determine the efficacy and safety of percutaneous irreversible electroporation combined with immunotherapy compared with irreversible electroporation alone in patients with locally advanced pancreatic ...
Miriana Mariussi, Laura Costa de Oliveira Lima, Mariano Gallo Ruelas, Victor Arthur Ohannesian, Bruno Murad, Guilherme Strieder de Oliveira, Luiza Giuliani Schmitt, Giovanni Brondani Torri, Stephan Altmayer, Priscila Mina Falsarella, Pedro Luiz Serrano Usón Junior, Rodrigo Gobbo Garcia   +11 more
doaj   +2 more sources

The Effect of Conductivity Changes on Temperature Rise During Irreversible Electroporation

Frontiers in Biomedical Technologies, 2020
Purpose: Irreversible electroporation is a physical process which is used for killing the cancer cells. The process that leads to cell death in this method is a unique process. Thermal damage does not exist in this process.
Amir Khorasani
doaj   +1 more source

Interrogation on the Cellular Nano-Interface and Biosafety of Repeated Nano-Electroporation by Nanostraw System

Biosensors, 2022
Cell perforation is a critical step for intracellular drug delivery and real-time biosensing of intracellular signals. In recent years, the nanostraws system has been developed to achieve intracellular drug delivery with minimal invasiveness to the cells.
Aihua Zhang, Jiaru Fang, Ji Wang, Xi Xie, Hui-Jiuan Chen, Gen He   +5 more
doaj   +1 more source

The effects of electroporation on viability and quality of in vivo-derived bovine blastocysts

The Journal of Reproduction and Development, 2019
The introduction of exogenous molecules into embryos is required for analyses of molecular dynamics and specific gene functions during early embryonic development. Electroporation is an effective method to transport exogenous molecules into cells, but is
Fuminori TANIHARA, Maki HIRATA, Shigeki MORIKAWA, Nhien Thi NGUYEN, Quynh Anh LE, Takayuki HIRANO, Yoshiyuki FUKUMI, Toshiaki ABE, Takeshige OTOI   +8 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Calcium Electroporation: Evidence for Differential Effects in Normal and Malignant Cell Lines, Evaluated in a 3D Spheroid Model. [PDF]

PLoS ONE, 2015
Calcium electroporation describes the use of high voltage electric pulses to introduce supraphysiological calcium concentrations into cells. This promising method is currently in clinical trial as an anti-cancer treatment. One very important issue is the
Stine Krog Frandsen, Laure Gibot, Moinecha Madi, Julie Gehl, Marie-Pierre Rols   +4 more
doaj   +1 more source

CRISPR-Cas9 Gene Editing of Hematopoietic Stem Cells from Patients with Friedreich's Ataxia. [PDF]

, 2020
Friedreich's ataxia (FRDA) is an autosomal recessive neurodegenerative disorder caused by expansion of GAA repeats in intron 1 of the frataxin (FXN) gene, leading to significant decreased expression of frataxin, a mitochondrial iron-binding protein.
Cherqui, Stephanie, Haquang, Joseph H, Luebeck, Jens, Mali, Prashant, Rainaldi, Joseph N, Rocca, Celine J, Sharma, Jay, Shi, Yanmeng   +7 more
core  

Tumour cell labelling by magnetic nanoparticles with determination of intracellular iron content and spatial distribution of the intracellular iron [PDF]

, 2013
: Magnetically labelled cells are used for in vivo cell tracking by MRI, used for the clinical translation of cell-base therapies. Studies involving magnetic labelled cells may include separation of labelled cells, targeted delivery and controlled ...
Alexiou, Alexiou, Alfred Cuschieri, Amemiya, Brekke, Buerli, Bulte, Bulte, Corot, Foster, Frank, Frimpong, Furlani, Hong, Hoskins, Huberman, Ivkov, Jiang, Kamau, Lee, Lewin, Liu, Matuszewski, Mykhaylyk, Oudkerk, Park, Pinkse, Prentice, Riemer, Shen, Sun, Sykova, Thorek, Walczak, Wang, Wang, Wu, Zhang, Zhang, Zhang, Zhigang Wang, Zhu   +41 more
core   +5 more sources