Results 1 to 10 of about 12,336 (156)

Multifocal Electroretinography

Delhi Journal of Ophthalmology, 2010
Visual electrophysiological tests provide information about the functional integrity of the pigment epithelium (Electrooculogram or EOG), the photoreceptors and inner layers of the retina (electroretinogram or ERG), and the optic nerve and occipital ...
Lalit Aalok, Swati Phuljhele
doaj   +4 more sources

Neuroprotective Effect of Methylene Blue in a Rat Model of Traumatic Optic Neuropathy [PDF]

Pharmaceuticals
Background: Traumatic optic neuropathy (TON) represents a major cause of vision loss worldwide, and treatment options are limited. Here, we study whether methylene blue (MB), a free radical scavenger, is able to prevent morphological and ...
Nicolás S. Ciranna, Ronan Nakamura, Rafael Peláez, Álvaro Pérez-Sala, Patricia Sarrión, Juan C. Fernández, Alejandra Paganelli, Agustín P. Aranalde, Ulises P. Ruiz, Juan J. López-Costa, César F. Loidl, Alfredo Martínez, Manuel Rey-Funes   +12 more
doaj   +2 more sources

Serotonin Signaling Pathway Modulation Affects Retinal Neuron Survival in Experimental Model of Retinal Ischemia [PDF]

Life
Serotonin is a key neurotransmitter involved in visual processing. Selective serotonin reuptake inhibitors (SSRIs), such as Escitalopram, enhance serotonergic transmission and exert neuroprotective effects.
Joanna Machowicz, Klaudia Mróz, Anna Pacwa, Anna Gąsiorek, Piotr Rodak, Joanna Lewin-Kowalik, Marialaura Amadio, Adrian Smędowski   +7 more
doaj   +2 more sources

Atypical Retinitis Pigmentosa With Systemic Features in Bardet–Biedl Syndrome [PDF]

Clinical Case Reports
Recognition of systemic features such as polydactyly in a patient with retinitis pigmentosa is crucial for early diagnosis of Bardet–Biedl syndrome. Mild non‐pitting swelling of the hands—an incidental, non‐classical finding—was also noted, emphasizing ...
Muhammad Umar Ahsan, Saba Shaheen, Somaiya Ahmed   +2 more
doaj   +2 more sources

Evaluation of the Ophthalmotoxic Effect of Quantum Dots and Bioconjugates Based on Them in Terms of the Prospects for the Treatment of Resistant Endophthalmitis. Experimental Research (Stage 1)

Oftalʹmologiâ, 2021
Endophthalmitis remains one of the most formidable complications of surgery in ophthalmology, leading to significant functional and anatomical changes. The “gold” standard of treatment for this pathology is the installation of intravenous injections of ...
V. O. Ponomarev, V. N. Kazaykin, A. V. Lizunov, A. S. Vokhmintsev, I. A. Vainshtein, S. V. Dezhurov   +5 more
doaj   +1 more source

Rescue of photoreceptor with human mesenchyme stem cell and human mesenchyme stem cell expressing erythropoietin in total degeneration of retina animal model

Indian Journal of Ophthalmology, 2022
Purpose: This study aimed to investigate the efficacy of human-derived umbilical cord mesenchymal stem cells (HDUMSC) and human-derived umbilical cord mesenchymal stem cells expressing erythropoietin (HDUMSC-EPO) to rescue total degenerated retina in a ...
Munirah Abd Rashid, Lam Chenshen, Avin Koh Ee Hwan, Hiba AlSaeedy, Pooi Ling Mok, Suresh Kumar Subbiah, Hazlita Md Isa, Then Kong Yong, Mohd Hairul Nizam Harun, Syed Mohamed Suhail B S Mohamad, Angela Ng Min Hwei, Chi D Luu, Mae-Lynn Catherine Bastion   +12 more
doaj   +1 more source

Structure and function of retinal ganglion cells in subjects with a history of repeated traumatic brain injury

Frontiers in Neurology, 2022
This study tested whether repeated traumatic brain injuries (TBIs) alter the objective structure or the objective function of retinal ganglion cells (RGCs) in human subjects recruited from an optometry clinic.
Kelly R. Klimo, Elizabeth A. Stern-Green, Erica Shelton, Elizabeth Day, Lisa Jordan, Matthew Robich, Julie Racine, Catherine E. McDaniel, Dean A. VanNasdale, Phillip T. Yuhas   +9 more
doaj   +1 more source

OculusGraphy: Signal Analysis of the Electroretinogram in a Rabbit Model of Endophthalmitis Using Discrete and Continuous Wavelet Transforms

Bioengineering, 2023
Background: The electroretinogram is a clinical test used to assess the function of the photoreceptors and retinal circuits of various cells in the eye, with the recorded waveform being the result of the summated response of neural generators across the ...
Aleksei Zhdanov, Paul Constable, Sultan Mohammad Manjur, Anton Dolganov, Hugo F. Posada-Quintero, Aleksander Lizunov   +5 more
doaj   +1 more source

Intraocular Adeno-Associated Virus-Mediated Transgene Endothelin-1 Delivery to the Rat Eye Induces Functional Changes Indicative of Retinal Ischemia—A Potential Chronic Glaucoma Model

Cells, 2023
Endothelin-1 (ET-1) overactivity has been implicated as a factor contributing to glaucomatous neuropathy, and it has been utilized in animal models of retinal ischemia.
Karin M. L. Nordahl, Vadim Fedulov, Anja Holm, Kristian A. Haanes   +3 more
doaj   +1 more source

Liposome-Mediated Delivery Improves the Efficacy of Lisosan G against Retinopathy in Diabetic Mice

Cells, 2023
Nutraceuticals are natural substances whose anti-oxidant and anti-inflammatory properties may be used to treat retinal pathologies. Their efficacy is limited by poor bioavailability, which could be improved using nanocarriers. Lisosan G (LG), a fermented
Rosario Amato, Alberto Melecchi, Laura Pucci, Alessio Canovai, Silvia Marracci, Maurizio Cammalleri, Massimo Dal Monte, Carla Caddeo, Giovanni Casini   +8 more
doaj   +1 more source