Results 151 to 160 of about 230,711 (334)

Disruption of Gut Microbiota‐Mediated De Novo NAD+ Synthesis Contributes to the Development of Polycystic Ovary Syndrome

Advanced Science, EarlyView.
This study demonstrates that patients with PCOS exhibit altered gut microbial profiles, and FMT from PCOS patients induces PCOS‐like symptoms in mice. Specifically, gut dysbiosis reduces 3‐HAA levels in the context of PCOS. Administration of 3‐HAA to mice alleviates PCOS by promoting de novo NAD+ synthesis.
Ke Chen, Huafeng Geng, Yang Zheng, Hongyang Xie, Rui Qin, Junyang Chen, Cong Ye   +6 more
wiley   +1 more source

Electrospray ionization mass spectrometry of zinc, cadmium, and copper metallothioneins: Evidence for metal‐binding cooperativity [PDF]

, 2000
Peter Gehrig, Chunhui You, Jeremias H.R. Kägi, Peter Hunziker, Reinhard Dallinger, Christine Gruber, Marius Brouwer   +6 more
openalex   +1 more source

Compositional Analysis of Adsorbed Organic Aerosol on a Microresonator Mass Sensor [PDF]

, 2018
Campbell, Steven J., Giorio, Chiara, Jones, Roderic L., Kalberer, Markus, Seshia, Ashwin A., Zielinski, Arthur T.   +5 more
core   +1 more source

A Lipid with Lewis Pair‐Mediated Targeting and Multiple Stimuli‐Responsive Delivery of Antibiotics for Bacterial Infections

Advanced Science, EarlyView.
Lewis pair‐integrated lipids (Lp‐lipids), combining targeted delivery and stimuli‐responsive are developed for antibiotic delivery. These lipids form nanoparticles that bind biofilms via boronate ester bonds and respond to acidic pH, H2O2, and ATP, enabling controlled drug release.
Xiaojian Yan, Lei Hua, Hongping Wan, Yong Liu, Tao Jin, Yicen Ge, Michael R Hamblin, Mahdi Karimi, Xinghong Zhao, Yan Hu, Linqi Shi, Yuanfeng Li   +11 more
wiley   +1 more source

Deuterium exchange of α‐helices and β‐sheets as monitored by electrospray ionization mass spectrometry

, 1994
David S. Wagner, Laura G. Melton, Yibing Yan, Bruce W. Erickson, Robert J. Anderegg   +4 more
openalex   +1 more source

Characterization of the interface structure of enzyme‐inhibitor complex by using hydrogen‐deuterium exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry [PDF]

, 2000
Satoko Akashi, Koji Takio
openalex   +1 more source

Ozone Oxidizes Glutathione to a Sulfonic Acid [PDF]

, 2009
Biosurfaces are universally covered with fluid microfilms containing reduced glutathione (GSH) and other antioxidants whose putative roles include the detoxification of ambient ozone (O_3).
Colussi, A. J., Enami, Shinichi, Hoffmann, M. R.   +2 more
core   +1 more source

H3K27ac Is Essential for Human Naive Pluripotency Modulated by m6A‐Driven EP300 Expression

Advanced Science, EarlyView.
An et al. reveal H3K27ac elevation is essential for establishing and maintaining human naive pluripotency; its inhibition disrupts this state while enhancement promotes it. METTL3‐mediated m6A modification indirectly controls H3K27ac by suppressing EP300 expression. Reduced EP300 lowers H3K27ac, impeding naive pluripotency.
Chenrui An, Ke Zhong, Xiangjin Kang, Yingying Zhang, Yudan Shang, Hao Liu, Yushan Ji, Jinbei Zeng, Jiajin Lin, Long Jin, Zelong Lin, Yang Yu, Xuetao Shi, Yong Fan   +13 more
wiley   +1 more source

Tandem mass spectrometry of multiply charged proteins with electrospray ionization

, 1992
Joseph A. Loo, Richard Smith
openalex   +2 more sources

Determination of glycosylation sites, disulfide bridges, and the C‐terminus of Stereum purpureum mature endopolygalacturonase I by electrospray ionization mass spectrometry [PDF]

, 2000
Tetsuya Shimizu, Kazuo Miyairi, Toshikatsu Okuno   +2 more
openalex   +1 more source