Arthritis &Rheumatology, Accepted Article.Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama +16 more
wiley +1 more source
Improvement of Electrospray Ionization Response Linearity and Quantification in Dissolved Organic Matter Using Synthetic Deuterated Internal Standards. [PDF]
Anal ChemCraig AJ +7 more
europepmc +1 more source
Molecular characterization of S‐ and N‐containing organic constituents in ambient aerosols by negative ion mode high‐resolution Nanospray Desorption Electrospray Ionization Mass Spectrometry: CalNex 2010 field study [PDF]
, 2014 Rachel E. O’Brien +5 more
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg +7 more
wiley +1 more source
A Strategy to Achieve Sub-Parts-per-Million Mass Measurement Accuracy of N-Linked Glycans Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization. [PDF]
J Mass SpectromAdepoju AA +3 more
europepmc +1 more source
Elucidating the Role of Ion Suppression in Secondary Electrospray Ionization. [PDF]
J Am Soc Mass Spectrom, 2023 Wüthrich C, Giannoukos S, Zenobi R.
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Tranexamic acid (TXA) stabilizes clot formation by inhibiting fibrin degradation and improves postoperative outcomes. However, rare adverse events (e.g., thrombosis, seizures) warrant dose–risk evaluation. This study examines how perioperative blood loss and transfusion practices affect TXA concentrations during paediatric scoliosis surgery ...
Paula Alexandra Sá +4 more
wiley +1 more source
Analysis of Acyl Solamines in Tuber Periderm of Cultivated and Wild Potatoes Using Liquid Chromatography Coupled With Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry. [PDF]
J Mass SpectromBöttcher C +3 more
europepmc +1 more source