Results 101 to 110 of about 203,215 (351)

Online investigation of lignin depolymerization via reactor-integrated electrospray ionization high-resolution mass spectrometry

open access: yesApplications in Energy and Combustion Science, 2022
Depolymerization of lignin can yield phenolic monomeric platform molecules, but depolymerization and repolymerization are proposed as concurrent processes, which greatly limit the yield of monomeric products.
Cunhao Cui   +7 more
doaj  

Probing the nature of interactions in SH2 binding interfaces–evidence from electrospray ionization mass spectrometry [PDF]

open access: bronze, 1999
Evonne W. Chung   +7 more
openalex   +1 more source

Crystalline‐Amorphous Heterostructure: A Novel Configuration for Silver Nanoclusters

open access: yesAdvanced Science, EarlyView.
This study presents a spontaneously formed amorphous‐crystalline heterostructure composite composed of atomically precise carboranylthiolate‐protected silver NCs, demonstrating not only a unique co‐assembly of distinct metal NCs at the macroscopic level but also promising potential applications of metal cluster‐based materials.
Jia‐Hong Huang   +4 more
wiley   +1 more source

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang   +15 more
wiley   +1 more source

Novel Cyano‐Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment

open access: yesAdvanced Science, EarlyView.
A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen   +9 more
wiley   +1 more source

Counterbalancing O‐GlcNAcylation and STAT3 Phosphorylation in Ventral Tegmental Area Dopaminergic Neurons Mediates Behavioral Adaptations to Acute Restraint Stress

open access: yesAdvanced Science, EarlyView.
Acute restraint stress enhances STAT3Ser727 phosphorylation in dopaminergic neurons in mice. This modification promotes the upregulation of GABBR2 and GABRB3, reduces neuronal activity, and contributes to anxiety‐like behavior and diminished reward‐seeking following stress exposure.
Mingshuo Shao   +10 more
wiley   +1 more source

Electrospray ionization mass spectrometry of zinc, cadmium, and copper metallothioneins: Evidence for metal‐binding cooperativity [PDF]

open access: bronze, 2000
Peter Gehrig   +6 more
openalex   +1 more source

Fully Automated Deep Learning Enabled Miniature Mass Spectrometry System for Psychoactive Therapeutic Drug Monitoring

open access: yesAdvanced Science, EarlyView.
This study presents a fully automated miniature mass spectrometry system for high‐throughput therapeutic drug monitoring. Integrating magnetic solid‐phase extraction, self‐aspiration sampling miniature mass spectrometer, and U‐net deep learning quantitative algorithm, it achieves rapid (8 samples/30 min), precise (R2 > 0.99, RSD < 10%), and portable ...
Yuanhao Zhou   +10 more
wiley   +1 more source

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