Results 141 to 150 of about 195,406 (308)
Cytoskeleton, EarlyView.ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen +2 more
wiley +1 more source
ChemPhysChem, Volume 26, Issue 6, March 15, 2025.The ionization of anthracene, acridine, and phenazine has been explored, along with the removal of one and two hydrogen atoms, to provide valuable information for astrochemists and to understand the behavior of the resulting structures and their electronic reorganization. Abstract In this study, we systematically explored the stability and isomerism of
Khaldia Zghida +3 more
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desorption electrospray ionization mass spectrometry
Citation: 'desorption electrospray ionization mass spectrometry' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09181 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.
openaire +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer +24 more
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Forensic DNA fingerprinting by liquid chromatography-electrospray ionization mass spectrometry
BioTechniques, 2007 Herbert Oberacher, Walther Parson
doaj +1 more source
Detection of homogentisic acid by electrospray ionization mass spectrometry. [PDF]
J Clin Lab Anal, 2023 Tokuhara Y +4 more
europepmc +1 more source
Drug Testing and Analysis, EarlyView.New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley +1 more source
Drug Testing and Analysis, EarlyView.Concentration ranges, dose–concentration relationships, and metabolite‐to‐parent drug ratios of therapeutic opioids were evaluated in hair and skin swab samples of 150 pediatric patients. Skin‐derived matrices such as sweat or sebum were shown to contribute to analyte incorporation into hair in a systematic manner.
Max Polke +7 more
wiley +1 more source
Method validation of clonidine hydrochloride in human plasma by LC-MS technique
Pharmaceutical and Biomedical Research, 2015 A simple and sensitive high performance liquid chromatography-electrospray ionization mass spectrometry method has been evaluated for the assignment of clonidine hydrochloride in human plasma.
Hossein Danafar
doaj
Identification of Metabolites of the Dietary Supplement Ingredient 5α‐Hydroxy‐Laxogenin
Drug Testing and Analysis, EarlyView.The biotransformation of the dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated using human HepG2 cells, the rat and in silico using the online software Next‐gen E‐Resource for Drug Discovery (NERDD). We identified five metabolites generated by the human HepG2 cells of which three and an additional mono‐hydroxylated metabolite were ...
Daniel Derwand +3 more
wiley +1 more source