Results 221 to 230 of about 3,602,918 (298)

Gold‐Catalyzed Cyclization of Indole‐Tethered Alkynes Enabling Synthesis of Exocyclic Alkenyl Tetrahydrocarbazoles

European Journal of Organic Chemistry, EarlyView.
An efficient gold‐catalyzed intramolecular cyclization of indole‐tethered alkynes using AgNTf2 as an additive has been developed, which provides bioactive exocyclic alkenyl tetrahydrocarbazoles with up to 85% yield. Control experiments and DFT studies indicate that the reaction proceeds via a 6‐exo‐dig cyclization pathway, with gold acetylide complexes
Haibo Mei, Jingrui He, Chengting Wang, Jorge Escorihuela, Jianlin Han   +4 more
wiley   +1 more source

A Fast-Pass, Desorption Electrospray Ionization Mass Spectrometry Strategy for Untargeted Metabolic Phenotyping. [PDF]

J Am Soc Mass Spectrom
Shepard HS, May JC, Zuniga BE, Abraham JP, Pfleger BF, Young JD, McLean JA.   +6 more
europepmc   +1 more source

Capillary Electrophoresis Methods for the Characterization of Synthetic Nanoparticles

ELECTROPHORESIS, EarlyView.
Capillary electrophoresis (CE) can be applied to evaluate nanoparticle (NP) size, charge, and surface characteristics. Hyphenating CE with ICP‐MS and AF4 can provide comprehensive, multidimensional NP characterization. ABSTRACT Nanoparticles (NPs) exhibit properties distinct from bulk materials of identical chemical composition, with their behavior and
Jordy D. Kruijswijk, Thomas Holmark, Kevin Jooß, Govert W. Somsen   +3 more
wiley   +1 more source

Imprint Desorption Electrospray Ionization Mass Spectrometry Imaging (IDESI-MSI) Reveals Absorption of Triclopyr-Based Herbicide in Plants and Mouse Organs. [PDF]

Metabolites
Liu H, Tian Y, Wei R, Meng Y, Zare RN.
europepmc   +1 more source

Improving the Sensitivity in Chiral Analysis by Capillary Electrophoresis

ELECTROPHORESIS, EarlyView.
Most recent advances for the enhancement of sensitivity in capillary electrophoresis, including off‐line and in‐capillary preconcentration techniques and their combinations, and the use of alternative detection systems to UV–Vis spectrophotometric absorption.
María Castro‐Puyana, Sandra Salido‐Fortuna, María Luisa Marina   +2 more
wiley   +1 more source

Charging of DNA Complexes in Positive-Mode Native Electrospray Ionization Mass Spectrometry. [PDF]

J Am Soc Mass Spectrom
Abramsson ML, Persson LJ, Sobott F, Marklund EG, Landreh M.   +4 more
europepmc   +1 more source

Antiseizure potency and neurotoxicity of the enantiomers of fenfluramine and norfenfluramine in rats and correlations with their concentrations in plasma and brain

Epilepsia, EarlyView.
Abstract Objective Based on the evidence that fenfluramine‐induced anorexia, weight loss, and cardiovascular toxicity are primarily mediated by the d‐enantiomers of fenfluramine and its metabolite norfenfluramine, we investigated pharmacokinetic/pharmacodynamic correlations for the active enantiomers of fenfluramine and norfenfluramine in the rat ...
Yara Sheeni, Dinorah Barasch, Tawfeeq Shekh‐Ahmad, Emilio Perucca, Meir Bialer   +4 more
wiley   +1 more source

Delineation of Subcellular Molecular Heterogeneity in Single Cells via Ultralow-Flow-Rate Desorption Electrospray Ionization Mass Spectrometry Imaging. [PDF]

Anal Chem
Zhang H, Shi X, Lu H, Li L.
europepmc   +1 more source

Real‐world evaluation of capillary microsampling for drug monitoring of anti‐seizure medications

Epilepsia, EarlyView.
Abstract Objective Capillary microsampling offers a minimally invasive alternative to venipuncture for therapeutic drug monitoring (TDM) of anti‐seizure medications (ASMs). We evaluated the feasibility and reliability of volumetric absorptive microsampling (VAMS) and quantitative dried blood spot (qDBS) devices for ambulatory self‐collection and at ...
Chiara Cancellerini, Alice Caravelli, Martina Soldà, Erika Esposito, Luca Vignatelli, Barbara Mostacci, Jessica Fiori, Francesca Bisulli, Laura Licchetta   +8 more
wiley   +1 more source

Direct Analysis of Solid-Phase Carbohydrate Polymers by Infrared Multiphoton Dissociation Reaction Combined with Synchrotron Radiation Infrared Microscopy and Electrospray Ionization Mass Spectrometry. [PDF]

Polymers (Basel)
Kawasaki T, Zen H, Nogami K, Hayakawa K, Sakai T, Hayakawa Y.   +5 more
europepmc   +1 more source