Results 81 to 90 of about 204,339 (353)
A Dual‐Emissive DNA‐Templated Silver Nanocluster with Near‐Infrared I and II Emission
This study presents a dual‐emissive DNA‐stabilized silver nanocluster with a nanosecond‐lived NIR‐I emission band and a microsecond‐lived NIR‐II emission band. Mass spectrometry establishes that the nanocluster has molecular formula (DNA)2[Ag17]11+. DNA sequence variations reveal critical nucleobases for stabilization, and modifications at the DNA 5 ...
Anna Gonzàlez‐Rosell +6 more
wiley +1 more source
An Organic Chemist’s Guide to Electrospray Mass Spectrometric Structure Elucidation
Tandem mass spectrometry is an important tool for structure elucidation of natural and synthetic organic products. Fragmentation of odd electron ions (OE+) generated by electron ionization (EI) was extensively studied in the last few decades, however ...
Arnold Steckel, Gitta Schlosser
doaj +1 more source
Influence of the sebaceous gland density on the stratum corneum lipidome [PDF]
The skin surface lipids (SSL) result from the blending of sebaceous and epidermal lipids, which derive from the sebaceous gland (SG) secretion and the permeability barrier of the stratum corneum (SC), respectively.
Camera, Emanuela +5 more
core +1 more source
Amphiphilic chloroazobenzenes, bearing different amino acids as end groups alanine, phenylalanine, and valine, exhibit excellent photoisomerizations. Varying structures of three amino acid groups participate in supramolecular formations and therefore photoinduced morphological transformations via adjusting intermolecular interactions. These interaction
Shuangshuang Meng +3 more
wiley +1 more source
Direct Ambient Analysis of Pharmaceutical and Ecstasy Tablets
Desorption electrospray ionization (DESI) is a new ionization technique recently introduced in analytical chemistry for the ambient analysis of surfaces by mass spectrometry.
Luc Alexis Leuthold +6 more
doaj +1 more source
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization [PDF]
Background Recent findings demonstrated that, in mammalian cells, telomere DNA (Tel) is transcribed into telomeric repeat-containing RNA (TERRA), which is involved in fundamental biological processes, thus representing a promising anticancer target. For
Alcaro, Stefano +11 more
core +1 more source
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
We investigated the fragmentation of the eudesmanolide-type sesquiterpene lactones 1α-(4-hydroxymethacryloyloxy)-3α,4α-epoxy-8α-hydroxyeudesm-11(13)-6α,12-olide (1) and 1α-(2,3-epoxyangeloyloxy)-4α,15-epoxy-8α-hydroxyeudesm-11(13)-6α,12-olide (2) by ...
Herbert Júnior Dias +4 more
doaj +1 more source
We have noted some inaccuracies in Table 1 and Table 2 of our article “Evaluation of the Broad-Range PCR-Electrospray Ionization Mass Spectrometry (PCR/ESI-MS) System and Virus Microarrays for Virus Detection” (Viruses 2014, 6, 1876–1896) [1].[...]
Lanyn P. Taliaferro +6 more
doaj +1 more source
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva +28 more
wiley +1 more source

