Results 61 to 70 of about 2,688,547 (318)

Antimicrobial susceptibility of enterobacterales causing bloodstream infection in United States medical centres: comparison of aztreonam-avibactam with beta-lactams active against carbapenem-resistant enterobacterales

open access: yesBMC Infectious Diseases
Background Bloodstream infection (BSI) is associated with poor outcomes especially when effective antimicrobial therapy and control of infection source are delayed.
Helio S. Sader   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Determination of 16 Selected Trace Elements in Children Plasma from China Economical Developed Rural Areas Using High Resolution Magnetic Sector Inductively Coupled Mass Spectrometry

open access: yesJournal of Analytical Methods in Chemistry, 2014
A rapid, accurate, and high performance method of high resolution sector field inductively coupled plasma mass spectrometry (HR-ICP-MS) combined with a small-size sample (0.1 mL) preparation was established.
Xiaobing Liu   +6 more
doaj   +1 more source

Asymmetric Catalysis in the Cyclometallation Reaction

open access: yesCHIMIA, 1978
The formation of optically active cyclopalladated products starting from dimethylaminomethylferrocene has been observed for the first time using the salts of optically active acids as basic catalysts.
Vyatcheslav I. Sokolov   +1 more
doaj   +1 more source

Time-independent hybrid enrichment for finite element solution of transient conduction–radiation in diffusive grey media [PDF]

open access: yes, 2013
We investigate the effectiveness of the partition-of-unity finite element method for transient conduction–radiation problems in diffusive grey media. The governing equations consist of a semi-linear transient heat equation for the temperature ?eld and a ...
Mohamed, M.S.   +7 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Activity of aztreonam-avibactam and ceftazidime-avibactam against β-lactamase-producing enterobacterales Isolates from United States hospitals

open access: yesJournal of Global Antimicrobial Resistance
Objectives: Enterobacterales isolates producing β-lactamases are widespread and threaten the use of β-lactams. This study evaluated the activity of aztreonam-avibactam and comparator antimicrobial agents against Enterobacterales isolates producing common
Lalitagauri M Deshpande   +3 more
doaj   +1 more source

The coupled dual boundary element-scaled boundary finite element method for efficient fracture mechanics [PDF]

open access: yes, 2012
A novel numerical method is presented for applications to general fracture mechanics problems in engineering. The coupled dual boundary element-scaled boundary finite element method (DBE-SBFEM) incorporates the numerical accuracy of the SBFEM and the ...
BIRD, GARETH,EDWARD
core  

A higher order control volume based finite element method to prodict the deformation of heterogeneous materials

open access: yes, 2013
Materials with obvious internal structure can exhibit behaviour, under loading, that cannot be described by classical elasticity. It is therefore important to develop computational tools incorporating appropriate constitutive theories that can capture ...
Wheel, Marcus   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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