Results 71 to 80 of about 339,404 (276)

Динамические способности российских компаний - введение в проблему [PDF]

, 2006
This working paper reviews the peculiarities of dynamic capabilities in Russian companies. Do they exist in Russian firms? The analysis of interview with top-managers of 9 firms from different industries is aimed the attempt to reveal the presence of the
Chayka, Victoria A., Kulikov, Alexander V.   +1 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Considerations on the Constructive Design of a Robotic Prehension Device Driven by Shape Memory Alloy Elements

Robotica & Management
This paper presents the 3D model of a robotic prehension device driven by shape memory alloy elements, starting from the constructive-functional scheme. The 3D models of the device components are shown first, and then the device assembly in two variants:
Daniel-Gheorghe Vela, Ion Vela, Calin-Octavian Miclosina   +2 more
doaj   +1 more source

A Convex Optimization-based Approach for Sidelobe Level Suppression and Null Control in Antenna Arrays by Displacing a Minimum Number of Elements

Journal of Telecommunications and Information Technology
This paper introduces two methods for peak sidelobe level (PSLL) reduction and null steering in the pattern of linear arrays using position control. While most research on this topic uses stochastic optimization techniques, here convex optimization and ...
Magdy A. Abdelhay
doaj   +1 more source

Modelling Mobile Objects in Open Distributed Systems

, 1995
ions Whole configurations should be treatable like single agents. This demands for hierarchies of nested object spaces which represent application structure. In the following, we briefly introduce the coordination model Objective Linda [5] which combines
Thilo Kielmann, Position Paper
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

A method to calibrate a specimen with strain gauges to measure force over the full-force range in high rate testing [PDF]

, 2009
This paper investigates a new method to calibrate a tensile specimen with strain gauges to measure force over the full range of loading at intermediate strain rate for use in high rate testing.
M. Williams, Peroni, L, Peroni, M, A. Pearce, Beaumont, Richard Adrian, L. Rubio, Avalle, Massimiliano, HASH(0x55a67fee1188), Schley, C. A., M.R. Wisnom, P.K.C. Wood, Rubio, Lourdes, L. Peroni, Wisnom, MR, J. Fernández-Sáez, PIERRON, Fabrice, R. Moulart, J. A. Loya, HALLLETT, Stephen R., Williams, Mark A, C. A. Schley, S.R. Hallett, Pearce, A., WISNOM, Michael R., Loya, José Antonio, Hallett, SR, Wood, P. K. C., C.A. Schley, Dallocchio, A, M. R. Wisnom, HALLETT, Stephen R., Pierron, F., Hallett, S. R., Williams, M. A. (Mark A.), A. Dallocchio, S. R. Hallett, R. Beaumont, Beaumont, R., Rusinek, A., Fernández-Sáez, José, M. Peroni, Wood, Paul, Moulart, R., Mayer, U, Peroni, Marco, PERONI M., Peroni, Lorenzo, Peroni, M., Pierron, F, MOULART, Raphaël, U. Mayer, P. K.C. Wood, Wisnom, M. R., Schley, C.A., A. Rusinek, Mayer, U., Dallocchio, A., F. Pierron, Moulart, R   +58 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

On the formulation of the planar ANCF triangular finite elements

, 2017
In this paper, new planar isoparametric triangular finite elements (FE) based on the absolute nodal coordinate formulation (ANCF) are developed. The proposed ANCF elements have six coordinates per node: two position coordinates that define the absolute ...
Tengfei Wang, Carmine M. Pappalardo, Pappalardo, Carmine M., Ahmed A. Shabana, Shabana, Ahmed A., Wang, Tengfei   +5 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source