Results 21 to 30 of about 2,525,455 (237)

Ellagic acid ameliorates cisplatin-induced acute kidney injury by regulating inflammation and SIRT6/TNF-α signaling

Food Science and Human Wellness, 2023
Despite cisplatin has been widely used in the treatment of various cancers, the noteworthy nephrotoxicity greatly constrained its clinical value. For this reason, finding novel targeted therapies to attenuate the nephrotoxicity of cisplatin should be ...
Yuqi Gao, Kezheng Peng, Yida Wang, Yannan Guo, Chenye Zeng, Rui Hua, Qingfei Liu, Xue Li, Ying Qiu, Zhao Wang   +9 more
doaj   +1 more source

Muscadine or amla extracts standardized to ellagic acid content ameliorate glucolipotoxicity associated β-cell dysfunction via inhibition of IL-1β and improved insulin secretion

Food Production, Processing and Nutrition, 2020
Glucolipotocixity induces IL-1 β secretion which impairs pancreatic β-cell insulin secretion. Ellagic acid and urolithin A have strong anti-inflammatory effect on cells. Muscadine and amla are very good sources of ellagic acid. The present study examined
Srikanth Earpina, Karen McDonough, Millicent Yeboah-Awudzi, Kristina J. Cook, Sita Aggarwal, Jack N. Losso   +5 more
doaj   +1 more source

Pharmacokinetics study of a supersaturatable self-microemulsifying drug delivery system for ellagic acid by UHPLC-Q-TOF-MS

Acta Pharmaceutica, 2021
To evaluate the bioavailability of ellagic acid loaded super-saturatable self-microemulsifying drug delivery system (S-SMEDDS), its pharmacokinetic properties were studied in rats with an ultra-high performance liquid chromatography-quadrupole time-of ...
Wang Jinglong, Fan Liqun, Zhang Lihua, Zheng Dandan, Wang Yingzi, Sun Xiao, Ji Yonghui   +6 more
doaj   +1 more source

Ellagic acid and its fermentative derivative urolithin A show reverse effects on the gp91-phox gene expression, resulting in opposite alterations in all-trans retinoic acid-induced superoxide generating activity of U937 cells

Biochemistry and Biophysics Reports, 2021
Ellagitannins (esters composed of glucose and ellagic acid) are hydrolyzed to generate ellagic acid in gut followed by conversion of ellagic acid to urolithins such as urolithin A by intestinal bacteria.
Hidehiko Kikuchi, Kaori Harata, Harishkumar Madhyastha, Futoshi Kuribayashi   +3 more
doaj   +1 more source

Role of Hydroxyapatite and Ellagic Acid in the Osteogenesis [PDF]

European Journal of Dentistry, 2020
Abstract Objective Ellagic acid (EA), a phenolic antioxidant, has benefits in bone health and wound healing. The combination of EA and hydroxyapatite (HA) (EA-HA) is expected to increase osteogenesis. The aim of this study was to analyze osteogenesis after application of EA-HA according to the number of osteoblasts and osteoclasts in the bone and the ...
Agung Satria Wardhana, Intan Nirwana, Hendrik Setia Budi, Meircurius Dwi Condro Surboyo   +3 more
openaire   +2 more sources

Ellagic Acid Increases Stress Resistance via Insulin/IGF-1 Signaling Pathway in Caenorhabditis elegans

Molecules, 2022
Ellagic acid is a natural polyphenol found in various fruits and vegetables. Numerous studies have shown that ellagic acid has beneficial effects on human health.
Shuju Bai, Yaoru Yu, Lu An, Wenbo Wang, Xueqi Fu, Jing Chen, Junfeng Ma   +6 more
doaj   +1 more source

Synthesis of ellagic acid glucoside using glucansucrase from Leuconostoc and characterization of this glucoside as a functional neuroprotective agent

AMB Express, 2021
Ellagic acid glucoside was synthesized via transglucosylation using sucrose and glucansucrase derived from Leuconostoc mesenteroides B-512 FMCM. After such enzymatic synthesis, the product was purified by 50% ethyl acetate fraction and C18 column ...
Hyejin Yu, Hana Jeong, Kwang-Yeol Yang, Jeong-Yong Cho, In Ki Hong, Seung-Hee Nam   +5 more
doaj   +1 more source

Protective Effects of Ellagic Acid Against Alcoholic Liver Disease in Mice

Frontiers in Nutrition, 2021
Ellagic acid, a natural polyphenolic compound commonly present in vegetables, fruits, nuts, and other edible plants, exerts many pharmacological activities.
Liang Zhao, Arshad Mehmood, Mohamed Mohamed Soliman, Asra Iftikhar, Maryam Iftikhar, Salama Mostafa Aboelenin, Chengtao Wang   +6 more
doaj   +1 more source

Protective Effects of Ellagic Acid on Testicular Ischemia-Reperfusion Injury in Rats

, 2023
Objective:This study aimed to investigate the protective effects of ellagic acid on testicular ischemia/reperfusion injury in rats.Materials and Methods:Twenty-one Sprague-Dawley rats were randomly divided into three groups: sham, ischemia/reperfusion (I/
AYDIN, Hasan Rıza, Ertuğrul Yiğit, Seyfi Kartal, Orhan Değer, ŞEKERCİ, Çağrı Akın, YİĞİT, Ertuğrul, Ramazanoglu, Mehmet Akif, TOPRAK, Tuncay, Mehmet Akif Ramazanoğlu, Ahmet Özgür Güçtaş, Hüseyin Kocagül, GüÜÇTAŞ, Ahmet Özgür, KARTAL, Seyfi, Çağrı Akın Şekerci, Hasan Rıza Aydın, Raziye Ergün, Ayten Livaoğlu, LİVAOĞLU, Ayten, DEĞER, Orhan, Tuncay Toprak, ERGÜN, Raziye, KOCAGÜL, Hüseyin   +21 more
core   +1 more source

The Effect of Ellagic Acid on Coagulation in Vivo [PDF]

Blood, 1966
Abstract Ellagic acid shortens the silicone and glass clotting times of the blood of dogs, cats, rabbits and rats. The silicone clotting time is reduced so as to make it almost equal to the normal glass clotting time for 5 to 30 minutes after the injection of the agent.
A, Girolami, D, Agostino, E E, Cliffton
openaire   +2 more sources