Results 101 to 110 of about 936,605 (354)
A 3D mechanical model of the early mammalian embryo [PDF]
, 2009 The early development of the mammalian embryo leads to the formation of a structure composed by an outer layer of polarized cells surrounding an inner mass of nonpolarized cells.
Dard, Nicolas +5 more
core +2 more sources
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Optimising image capture for low-light widefield quantitative fluorescence microscopy [PDF]
APL Photon. 10, 031102 (2025)Low-light optical imaging refers to the use of cameras to capture images with minimal photon flux. This area has broad application to diverse fields, including optical microscopy for biological studies. In such studies, it is important to reduce the intensity of illumination to reduce adverse effects such as photobleaching and phototoxicity that may ...
arxiv +1 more source
, 2015 Proteins are biomolecules responsible for a vast range of functions within living cells and tissues. Over 150 different proteins are present in the fluid of the oviduct, where mammalian oocytes are fertilized and zygotes start to develop.
P. Coy, R. Yanagimachi
semanticscholar +1 more source
Molecular human reproduction, 2014 Telomeres are located at the ends of all eukaryotic chromosomes and protect them from deleterious events such as inappropriate DNA repair, illegitimate recombination or improper segregation of the chromosomes during mitotic or meiotic divisions. However,
S. Ozturk, B. Sozen, N. Demir
semanticscholar +1 more source
Haemogenic endocardium contributes to transient definitive haematopoiesis. [PDF]
, 2013 Haematopoietic cells arise from spatiotemporally restricted domains in the developing embryo. Although studies of non-mammalian animal and in vitro embryonic stem cell models suggest a close relationship among cardiac, endocardial and haematopoietic ...
Arshi, Armin +14 more
core +1 more source
New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris
Advanced Materials Interfaces, EarlyView.Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini +7 more
wiley +1 more source
Oocyte specific lncRNA variant Rose influences oocyte and embryo development
Non-coding RNA Research, 2021 Fully grown mammalian oocytes store a large amount of RNA synthesized during the transcriptionally active growth stage. A large part of the stored RNA belongs to the long non-coding class which contain either transcriptional noise or important ...
Rajan Iyyappan +5 more
doaj
Advanced Therapeutics, EarlyView.Antimicrobial resistance necessitates the development of new antibiotics with “resistance‐breaking” properties. In this study, conjugation of polycationic peptides is proven to represent a versatile strategy for the fast and affordable reactivation of daptomycin.
Sari Rasheed +21 more
wiley +1 more source
Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 542-549, December 2022., 2022 Schematic diagram showing RHAU can bind and unwind the G4 “knots” to modulate embryonic development and post‐natal organ function. Deficiency of RHAU gives rise to embryonic lethality, impaired organogenesis and organ dysfunction. RHAU modulates Nkx2‐5 mRNA and Yap1 mRNA at the post‐transcriptional level and facilitates the transcription of c‐Kit and ...
Chensi Yang +5 more
wiley +1 more source