Results 171 to 180 of about 212,225 (290)

Human Development and Reconsideration of Ensoulment [PDF]

, 1993
Kischer, Clayton Ward
core   +1 more source

Programming Next‐Generation Synthetic Biosensors by Genetic Circuit Design

Advanced Science, EarlyView.
Synthetic biology enables genetic circuit‐based biosensing to detect diverse targets, process signals, and transduce them into readable outputs or intracellular regulatory activities. However, field deployment and real‐world application of such synthetic biosensors face considerable challenges in sensitivity, specificity, speed, stability, and ...
Yuanli Gao, Cheng Huang, Jiaxuan Deng, Lei Wang, Baojun Wang   +4 more
wiley   +1 more source

Definition of critical skin defect and concepts of structural and functional repairs: Proposal and verification in a rat model

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the research process regarding skin defect repair using a rat model of skin defect. First, it assesses whether the barrier function of the skin is repaired. If the answer is “YES”, the study proceeds to focus on structural repair.
Cong Sun, Weihong Guo, Fang Liang, Rabia Javed, Weijian Hou, Xingdong Zhang, Qiang Ao   +6 more
wiley   +1 more source

Stage-sensitive potential of isolated rabbit ICM to differentiate into extraembryonic lineages†. [PDF]

Biol Reprod
Filimonow K, Chołoniewska A, Chołoniewski J, Madeja ZE, Barłowska K, Grabarek J, Wenta-Muchalska E, Plusa B, Piliszek A.   +8 more
europepmc   +1 more source

Immunoisolation of centrosomes from Drosophila melanogaster [PDF]

, 2005
Lange, B., Lehmann, V., Müller, H.
core   +2 more sources

Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen, Xu Zhang, Rui Fan, Xia Li, Feifei Guan, Gefan Wan, Weining Kong, Xiaolong Qi, Shuo Pan, Sijing Shi, Yuanlong Su, Shan Gao, Wei Huang, Xunde Xian, Jiangning Liu, Yuhui Wang, Yuanwu Ma   +16 more
wiley   +1 more source

Fertilization triggers early proteomic symmetry breaking in mammalian embryos. [PDF]

Cell
Iwamoto-Stohl LK, Petelski AA, Quan B, Meglicki M, Fu A, Nakagawa S, McMahon B, Wang TY, Khan S, Specht H, Huffman G, Derks J, Junyent S, Weatherbee BAT, Weberling A, Gantner CW, Mandelbaum RS, Paulson RJ, Lam L, Chou TF, Slavov N, Zernicka-Goetz M.   +21 more
europepmc   +1 more source

Assessing Angiogenic Properties In Vitro or In Ovo of Pre‐Crosslinked Alginate‐Dialdehyde‐Gelatin Hydrogels Incorporating Boron‐Doped Mesoporous Bioactive Glass Particles

Advanced NanoBiomed Research, EarlyView.
This study examines the influence of boron‐doped mesoporous bioactive glass nanoparticles (MBGN) blended in cast and 3D‐printed pre‐crosslinked alginate‐dialdehyde‐gelatin (ADA‐GEL). Addition of 0.5% and 1% MBGN did not negatively affect the viability of human umbilical vein endothelial cells (HUVECs), or the sprouting of HUVEC spheroids.
Rafael Schmid, Yvonne Kulicke, Evelin Sandor, Hsuan‐Heng Lu, Stefan Fleischer, Isabell Lang, Harald Wajant, Hana Kaňková, Andreas Arkudas, Annika Kengelbach‐Weigand, Raymund E. Horch, Aldo R. Boccaccini, Theresa Promny   +12 more
wiley   +1 more source

The Consequences of DNA Damage in the Early Embryo Are Important for Practical Procedures in Assisted Reproduction. [PDF]

Int J Mol Sci
Baran V, Čikoš Š, Fabian D.
europepmc   +1 more source

Unlocking fruit dimensions: Quantification of functional traits driving plant–frugivore interactions

Applications in Plant Sciences, EarlyView.
Abstract Fleshy fruits attract animals to ingest fruit, swallow the seeds, and release them in the landscape, thus facilitating seed dispersal and plant regeneration. Attraction of animal dispersers is achieved via attractants such as color or scent, and rewards like sugars, lipids, and micronutrients.
Linh M. N. Nguyen, Evangelia Linda Chronopoulou, Gabriela A. S. Escaliante, Kim Valenta, Omer Nevo   +4 more
wiley   +1 more source