Results 11 to 20 of about 199,433 (310)
Cell arrest and cell death in mammalian preimplantation development [PDF]
, 2011 The causes, modes, biological role and prospective significance of cell death in preimplantation development in humans and other mammals are still poorly understood.
A Bettegowda +57 more
core +11 more sources
Nature Communications, 2022 Mammalian embryogenesis relies on glycolysis and oxidative phosphorylation, but understanding of the dynamics of metabolic regulation in the postimplantation embryo in vivo remains elusive.
Anna Malkowska +3 more
doaj +1 more source
PLoS Biology, 2021 Architectural changes at the cellular and organism level are integral and necessary to successful development and growth. During mammalian preimplantation development, cells reduce in size and the architecture of the embryo changes significantly.
Jessica E Forsyth +8 more
doaj +1 more source
Human embryos cultured in vitro to 14 days [PDF]
Open Biology, 2017 We know a great deal about the development of the mammalian embryo until the time that the blastocyst implants into the uterus. With model organisms such as the mouse, we have also developed a considerable understanding of development immediately around ...
Samantha A. Morris
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Post-Translational Modifications in Oocyte Maturation and Embryo Development
Frontiers in Cell and Developmental Biology, 2021 Mammalian oocyte maturation and embryo development are unique biological processes regulated by various modifications. Since de novo mRNA transcription is absent during oocyte meiosis, protein-level regulation, especially post-translational modification (
Yu Wu, Yu Wu, Mo Li, Mo Li, Mo Yang
doaj +1 more source
Chromatin remodeling in mammalian embryos [PDF]
Reproduction, 2018 The mammalian embryo undergoes a dramatic amount of epigenetic remodeling during the first week of development. In this review, we discuss several epigenetic changes that happen over the course of cleavage development, focusing on covalent marks (e.g., histone methylation and acetylation) and non-covalent remodeling (chromatin remodeling via remodeling
Birgit Cabot, Ryan A Cabot
openaire +3 more sources
Erythroid development in the mammalian embryo [PDF]
Blood Cells, Molecules, and Diseases, 2013 Erythropoiesis is the process by which progenitors for red blood cells are produced and terminally differentiate. In all vertebrates, two morphologically distinct erythroid lineages (primitive, embryonic, and definitive, fetal/adult) form successively within the yolk sac, fetal liver, and marrow and are essential for normal development. Red blood cells
Johnathan L. Nieves +2 more
openaire +3 more sources
Application of a Microfluidic Chip with Mechanical Stimuli for Culturing Mouse Embryos in vitro [PDF]
International Journal Bioautomation, 2018 In order to solve some problems of lower blastocyst rate of early embryos in vitro and poor quality of blastocyst, application of a microfluidic chip with mechanical stimuli (MS) to imitate microenvironment of fallopian tube, to investigate the effect of
Jingchun Li +5 more
doaj +1 more source
Developmental potential of aneuploid human embryos cultured beyond implantation
Nature Communications, 2020 Aneuploidy, abnormal chromosome number, is a major cause of early pregnancy loss. Here the authors determine the extent of post-implantation development of human embryos with common aneuploidies in culture, finding developmental arrest of monosomy 21 ...
Marta N. Shahbazi +11 more
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DNA methylation heterogeneity induced by collaborations between enhancers [PDF]
Journal of Computational Biology, 2020, 2020 During mammalian embryo development, reprogramming of DNA methylation plays important roles in the erasure of parental epigenetic memory and the establishment of na\"{i}ve pluripogent cells. Multiple enzymes that regulate the processes of methylation and demethylation work together to shape the pattern of genome-scale DNA methylation and guid the ...
arxiv +1 more source