Results 11 to 20 of about 206,297 (286)
Cell arrest and cell death in mammalian preimplantation development [PDF]
, 2011 The causes, modes, biological role and prospective significance of cell death in preimplantation development in humans and other mammals are still poorly understood.
A Bettegowda +57 more
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Human embryos cultured in vitro to 14 days [PDF]
Open Biology, 2017 We know a great deal about the development of the mammalian embryo until the time that the blastocyst implants into the uterus. With model organisms such as the mouse, we have also developed a considerable understanding of development immediately around ...
Samantha A. Morris
doaj +1 more source
Post-Translational Modifications in Oocyte Maturation and Embryo Development
Frontiers in Cell and Developmental Biology, 2021 Mammalian oocyte maturation and embryo development are unique biological processes regulated by various modifications. Since de novo mRNA transcription is absent during oocyte meiosis, protein-level regulation, especially post-translational modification (
Yu Wu, Yu Wu, Mo Li, Mo Li, Mo Yang
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Chromatin remodeling in mammalian embryos [PDF]
Reproduction, 2018 The mammalian embryo undergoes a dramatic amount of epigenetic remodeling during the first week of development. In this review, we discuss several epigenetic changes that happen over the course of cleavage development, focusing on covalent marks (e.g., histone methylation and acetylation) and non-covalent remodeling (chromatin remodeling via remodeling
Birgit Cabot, Ryan A Cabot
openaire +3 more sources
Erythroid development in the mammalian embryo [PDF]
Blood Cells, Molecules, and Diseases, 2013 Erythropoiesis is the process by which progenitors for red blood cells are produced and terminally differentiate. In all vertebrates, two morphologically distinct erythroid lineages (primitive, embryonic, and definitive, fetal/adult) form successively within the yolk sac, fetal liver, and marrow and are essential for normal development. Red blood cells
Johnathan L. Nieves +2 more
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Developmental potential of aneuploid human embryos cultured beyond implantation
Nature Communications, 2020 Aneuploidy, abnormal chromosome number, is a major cause of early pregnancy loss. Here the authors determine the extent of post-implantation development of human embryos with common aneuploidies in culture, finding developmental arrest of monosomy 21 ...
Marta N. Shahbazi +11 more
doaj +1 more source
Application of a Microfluidic Chip with Mechanical Stimuli for Culturing Mouse Embryos in vitro [PDF]
International Journal Bioautomation, 2018 In order to solve some problems of lower blastocyst rate of early embryos in vitro and poor quality of blastocyst, application of a microfluidic chip with mechanical stimuli (MS) to imitate microenvironment of fallopian tube, to investigate the effect of
Jingchun Li +5 more
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Biophysical models of early mammalian embryogenesis
Stem Cell Reports, 2023 Summary: Embryo development is a critical and fascinating stage in the life cycle of many organisms. Despite decades of research, the earliest stages of mammalian embryogenesis are still poorly understood, caused by a scarcity of high-resolution spatial ...
Alaina Cockerell +6 more
doaj +1 more source
Biosynthesis and expression of zona pellucida glycoproteins in mammals [PDF]
, 2001 The zona pellucida (ZP) is an extracellular matrix surrounding the oocyte and the early embryo that exerts several important functions during fertilization and early embryonic development.
Kölle, S. +2 more
core +1 more source
Embryo culture in presence of oviductal fluid induces DNA methylation changes in bovine blastocysts [PDF]
, 2017 During the transit through the oviduct, the early embryo initiates an extensive DNA methylation reprogramming of its genome. Given that these epigenetic modifications are susceptible to environmental factors, components present in the oviductal milieu ...
Barrera, Antonio Daniel +7 more
core +1 more source