Protocadherin-1 is expressed in the notochord of mouse embryo but is dispensable for its formation
Biochemistry and Biophysics Reports, 2021 Notochord is an embryonic midline structure that serves as mechanical support for axis elongation and the signaling center for the surrounding tissues.
Kanako Fukunaga +4 more
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The p66(Shc) adaptor protein controls oxidative stress response in early bovine embryos. [PDF]
PLoS ONE, 2014 The in vitro production of mammalian embryos suffers from high frequencies of developmental failure due to excessive levels of permanent embryo arrest and apoptosis caused by oxidative stress.
Dean H Betts +2 more
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Asynchronous mouse embryo polarization leads to heterogeneity in cell fate specification
eLifeThe first lineage allocation in mouse and human embryos separates the inner cell mass (ICM) from the outer trophectoderm (TE). This symmetry-breaking event is executed through polarization of cells at the 8 cell stage and subsequent asymmetric divisions,
Adiyant Lamba +11 more
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Epigenetic regulation in mammalian preimplantation embryo development
Reproductive Biology and Endocrinology, 2009 Preimplantation embryo development involves four stages: fertilization, cell cleavage, morula and blastocyst formation. During these stages, maternal and zygotic epigenetic factors play crucial roles.
Shi Lingjun, Wu Ji
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Reorganization, specialization, and degradation of oocyte maternal components for early development
Reproductive Medicine and Biology, 2023 Background Oocyte components are maternally provided, solely determine oocyte quality, and coordinately determine embryo quality with zygotic gene expression.
Yuhkoh Satouh, Ken Sato
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Effects of mammalian sex hormones on in vitro organogenesis of common bean (Phaseolus vulgaris L.)
Scientific Reports, 2023 Beans are an important plant species and are one of the most consumed legumes in human nutrition, especially as a protein, vitamin, mineral, and fiber source.
Kamil Haliloğlu +5 more
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FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
In Vitro Host-Cell Susceptibility to Usutu Virus
Emerging Infectious Diseases, 2005 We investigated the susceptibility to Usutu virus (Flavivirus) of 13 permanent cell lines, 3 primary cell cultures, and chicken embryos. Vero, PK-15, and goose embryo fibroblast cells developed cytopathic effects; however, viral multiplication was ...
Tamás Bakonyi +4 more
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