Results 21 to 30 of about 101,661 (268)
A Tale of Division and Polarization in the Mammalian Embryo [PDF]
Developmental Cell, 2017 The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass and the extra-embryonic trophectoderm. In this issue of Developmental Cell, Korotkevic and colleagues (2017) show that the interplay between cell polarization and cell-cell contact drives the segregation of these lineages, providing a framework for self ...
Srinivas, S, Rodriguez, TA
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Complications Associated with Uterine Artery Embolisation for Fibroids
Obstetrics and Gynecology International, 2012 Uterine artery embolisation (UAE) is a relative newcomer to the mainstream treatment modalities available for fibroid-related problems. The efficacy of UAE is indisputable and has been shown to be comparable to hysterectomy in the short term in large ...
Maria Memtsa, Hayden Homer
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Protocadherin-1 is expressed in the notochord of mouse embryo but is dispensable for its formation
Biochemistry and Biophysics Reports, 2021 Notochord is an embryonic midline structure that serves as mechanical support for axis elongation and the signaling center for the surrounding tissues.
Kanako Fukunaga +4 more
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Instructions for Assembling the Early Mammalian Embryo [PDF]
Developmental Cell, 2018 The preimplantation mouse embryo is a simple self-contained system, making it an excellent model to discover how mammalian cells function in real time and in vivo. Work over the last decade has revealed some key morphogenetic mechanisms that drive early development, yielding rudimentary instructions for the generation of a mammalian embryo.
White, Melanie D. +3 more
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The p66(Shc) adaptor protein controls oxidative stress response in early bovine embryos. [PDF]
PLoS ONE, 2014 The in vitro production of mammalian embryos suffers from high frequencies of developmental failure due to excessive levels of permanent embryo arrest and apoptosis caused by oxidative stress.
Dean H Betts +2 more
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Asynchronous mouse embryo polarization leads to heterogeneity in cell fate specification
eLifeThe first lineage allocation in mouse and human embryos separates the inner cell mass (ICM) from the outer trophectoderm (TE). This symmetry-breaking event is executed through polarization of cells at the 8 cell stage and subsequent asymmetric divisions,
Adiyant Lamba +11 more
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Epigenetic regulation in mammalian preimplantation embryo development
Reproductive Biology and Endocrinology, 2009 Preimplantation embryo development involves four stages: fertilization, cell cleavage, morula and blastocyst formation. During these stages, maternal and zygotic epigenetic factors play crucial roles.
Shi Lingjun, Wu Ji
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Reorganization, specialization, and degradation of oocyte maternal components for early development
Reproductive Medicine and Biology, 2023 Background Oocyte components are maternally provided, solely determine oocyte quality, and coordinately determine embryo quality with zygotic gene expression.
Yuhkoh Satouh, Ken Sato
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source