Results 261 to 270 of about 206,297 (286)
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DNA repair in mammalian embryos
Mutation Research/Reviews in Mutation Research, 2007Mammalian cells have developed complex mechanisms to identify DNA damage and activate the required response to maintain genome integrity. Those mechanisms include DNA damage detection, DNA repair, cell cycle arrest and apoptosis which operate together to protect the conceptus from DNA damage originating either in parental gametes or in the embryo's ...
S. Jaroudi, Sioban SenGupta
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The Regulative Nature of Mammalian Embryos
2018The striking developmental plasticity of early mammalian embryos has been known since the classical experiments performed in the 1950s and 1960s. There are many lines of evidence that the mammalian embryo is able to continue normal development even when exposed to severe experimental manipulations of the number and position of cells within the embryo ...
Anna Kasperczuk +2 more
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Symmetry Breaking in the Mammalian Embryo
Annual Review of Cell and Developmental Biology, 2018We present an overview of symmetry breaking in early mammalian development as a continuous process from compaction to specification of the body axes. While earlier studies have focused on individual symmetry-breaking events, recent advances enable us to explore progressive symmetry breaking during early mammalian development.
Takashi Hiiragi, Hui Ting Zhang
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Encapsulation of Mammalian Embryos
1999Encapsulation of mammalian preimplantation embryos has its origins in the work of Willadsen in the late 1970s and in the need to develop an artificial zona pellucida for denuded sheep, horse, and cattle embryos used in the production of monozygotic twins for the livestock industry.
Glen K. Adaniya, Richard G. Rawlins
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Nuclear Transfer in Mammalian Embryos
1990Publisher Summary This chapter discusses the nuclear transfer in mammalian embryos. Transfer of nuclei from one cell to another provides a powerful method to study the interactions of the cytoplasm of one cell with the nuclei of another. Nuclei from various differentiated states can be transferred to nondifferentiated cytoplasm and the effect on the ...
Neal L. First, Randall S. Prather
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Erythropoiesis in the mammalian embryo
Experimental HematologyRed blood cells (RBCs) comprise a critical component of the cardiovascular network, which constitutes the first functional organ system of the developing mammalian embryo. Examination of circulating blood cells in mammalian embryos revealed two distinct types of erythroid cells: large, nucleated "primitive" erythroblasts followed by smaller, enucleated
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Genetics of polarity in mammalian embryos
Reproductive BioMedicine Online, 2005This brief review is devoted to the genetic control of polarity and embryonic axes in preimplantation mammalian embryos. Discussion is related to their formation, the considerable variations in gene activity in these early phases of development, and the influence of timers over polarities and related aspects of development.
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Junctional Complexes in the Early Mammalian Embryo
Seminars in Reproductive Medicine, 2000Preimplantation embryos generate intercellular junctions during differentiation of the trophectoderm epithelium and the formation of the blastocyst. These membrane complexes comprise gap junctions, adherens junctions, tight junctions, and desmosomes, each performing fundamental roles in cellular communication, adhesion, and differentiation.
Fleming, T.P. +2 more
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Chapter 1 Ontogeny of Erythropoiesis in the Mammalian Embryo [PDF]
, 2008 Red cells are required not only for adult well-being but also for survival and growth of the mammalian embryo beyond early postimplantation stages of development. The embryo's first "primitive" erythroid cells, derived from a transient wave of committed progenitors, emerge from the yolk sac as immature precursors and differentiate as a semisynchronous ...
Kathleen E. McGrath, James Palis
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Cryopreservation of Mammalian Embryos
2000Embryo cryopreservation is now routine for major experimental and domestic animals. The absence of effective embryo cryopreservation technologies for other animals may result in major loss of genetic diversity. “Delipation” enables cryopreservation of the cryosensitive embryos.
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