Oocyte specific lncRNA variant Rose influences oocyte and embryo development
Non-coding RNA Research, 2021 Fully grown mammalian oocytes store a large amount of RNA synthesized during the transcriptionally active growth stage. A large part of the stored RNA belongs to the long non-coding class which contain either transcriptional noise or important ...
Rajan Iyyappan +5 more
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Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation
Nature Communications, 2019 How the shape of the pre-implantation murine embryo changes dramatically upon implantation is unclear. Here, the authors use live imaging with a cdx2-GFP reporter line in combination with loss of function experiments to demonstrate that FGF signalling ...
Neophytos Christodoulou +5 more
doaj +1 more source
Haemogenic endocardium contributes to transient definitive haematopoiesis. [PDF]
, 2013 Haematopoietic cells arise from spatiotemporally restricted domains in the developing embryo. Although studies of non-mammalian animal and in vitro embryonic stem cell models suggest a close relationship among cardiac, endocardial and haematopoietic ...
Arshi, Armin +14 more
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Editing DNA Methylation in Mammalian Embryos [PDF]
International Journal of Molecular Sciences, 2020 DNA methylation in mammals is essential for numerous biological functions, such as ensuring chromosomal stability, genomic imprinting, and X-chromosome inactivation through transcriptional regulation. Gene knockout of DNA methyltransferases and demethylation enzymes has made significant contributions to analyzing the functions of DNA methylation in ...
Taiga Yamazaki +4 more
openaire +2 more sources
The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature [PDF]
, 2010 In vertebrates, body musculature originates from somites, whereas head muscles originate from the cranial mesoderm. Neck muscles are located in the transition between these regions.
Christ, B. +9 more
core +1 more source
Insights into epigenetic patterns in mammalian early embryos
Protein & Cell, 2020 Mammalian fertilization begins with the fusion of two specialized gametes, followed by major epigenetic remodeling leading to the formation of a totipotent embryo. During the development of the pre-implantation embryo, precise reprogramming progress is a
Ruimin Xu +3 more
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Redundancy and compensation in axon guidance: genetic analysis of the Drosophila Ptp10D/Ptp4E receptor tyrosine phosphatase subfamily [PDF]
, 2008 Background: Drosophila has six receptor protein tyrosine phosphatases (RPTPs), five of which are expressed primarily in neurons. Mutations in all five affect axon guidance, either alone or in combination.
Bahri, Sami +3 more
core +4 more sources
Complications Associated with Uterine Artery Embolisation for Fibroids
Obstetrics and Gynecology International, 2012 Uterine artery embolisation (UAE) is a relative newcomer to the mainstream treatment modalities available for fibroid-related problems. The efficacy of UAE is indisputable and has been shown to be comparable to hysterectomy in the short term in large ...
Maria Memtsa, Hayden Homer
doaj +1 more source
Radial glia in the proliferative ventricular zone of the embryonic and adult turtle, Trachemys scripta elegans. [PDF]
, 2014 To better understand the role of radial glial (RG) cells in the evolution of the mammalian cerebral cortex, we investigated the role of RG cells in the dorsal cortex and dorsal ventricular ridge of the turtle, Trachemys scripta elegans.
Clinton, Brian K +4 more
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Protocadherin-1 is expressed in the notochord of mouse embryo but is dispensable for its formation
Biochemistry and Biophysics Reports, 2021 Notochord is an embryonic midline structure that serves as mechanical support for axis elongation and the signaling center for the surrounding tissues.
Kanako Fukunaga +4 more
doaj +1 more source