NANOG/GATA6 Interactions Revisited: A Statistical Mechanics Approach towards Cell Fate Decisions [PDF]
arXiv, 2021 In preimplantation mammalian embryos, the second cell fate decision introduces spatial patterns of embryonic and extra-embryonic precursor cells. The transcription factors NANOG and GATA6 are the earliest markers for the two cell types and interact between cells via the fibroblast growth factor signaling pathway.
arxiv
Eccentricity excitation and merging of planetary embryos heated by pebble accretion [PDF]
A&A 606, A114 (2017), 2017 Context: Planetary embryos can continue to grow by pebble accretion until they become giant planet cores. Simultaneously, these embryos mutually interact and also migrate due to torques arising from the protoplanetary disk. Aims: Our aim is to investigate how pebble accretion alters the orbital evolution of embryos undergoing the Type-I migration. In
arxiv +1 more source
Pre-implantation mouse embryos cultured In vitro under different oxygen concentrations show altered ultrastructures [PDF]
, 2020 Assisted Reproductive Technologies routinely utilize different culture media and oxygen (O2) concentrations to culture human embryos. Overall, embryos cultured under physiological O2 tension (5%) have improved development compared to embryos cultured ...
Antonouli, S +6 more
core +1 more source
The p66(Shc) adaptor protein controls oxidative stress response in early bovine embryos. [PDF]
PLoS ONE, 2014 The in vitro production of mammalian embryos suffers from high frequencies of developmental failure due to excessive levels of permanent embryo arrest and apoptosis caused by oxidative stress.
Dean H Betts +2 more
doaj +1 more source
A role for core planar polarity proteins in cell contact-mediated orientation of planar cell division across the mammalian embryonic skin [PDF]
, 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original ...
A Muller +47 more
core +2 more sources
Editing DNA Methylation in Mammalian Embryos [PDF]
International Journal of Molecular Sciences, 2020 DNA methylation in mammals is essential for numerous biological functions, such as ensuring chromosomal stability, genomic imprinting, and X-chromosome inactivation through transcriptional regulation. Gene knockout of DNA methyltransferases and demethylation enzymes has made significant contributions to analyzing the functions of DNA methylation in ...
Taiga Yamazaki +4 more
openaire +2 more sources
Reorganization, specialization, and degradation of oocyte maternal components for early development
Reproductive Medicine and Biology, 2023 Background Oocyte components are maternally provided, solely determine oocyte quality, and coordinately determine embryo quality with zygotic gene expression.
Yuhkoh Satouh, Ken Sato
doaj +1 more source
Linking planetary embryo formation to planetesimal formation I: The impact of the planetesimal surface density in the terrestrial planet zone [PDF]
, 2020 The growth time scales of planetary embryos and their formation process are imperative for our understanding on how planetary systems form and develop. They determine the subsequent growth mechanisms during the life stages of a circumstellar disk.
arxiv +1 more source
Epigenetic regulation in mammalian preimplantation embryo development
Reproductive Biology and Endocrinology, 2009 Preimplantation embryo development involves four stages: fertilization, cell cleavage, morula and blastocyst formation. During these stages, maternal and zygotic epigenetic factors play crucial roles.
Shi Lingjun, Wu Ji
doaj +1 more source
Gene therapy:the potential applicability of gene transfer technology to the human germline [PDF]
, 2004 The theoretical possibility of applying gene transfer methodologies to the human germline is explored. Transgenic methods for genetically manipulating embryos may in principle be applied to humans.
Smith, Kevin R.
core +2 more sources