Results 41 to 50 of about 208,388 (190)

A Tale of Division and Polarization in the Mammalian Embryo [PDF]

open access: yesDevelopmental Cell, 2017
The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass and the extra-embryonic trophectoderm. In this issue of Developmental Cell, Korotkevic and colleagues (2017) show that the interplay between cell polarization and cell-cell contact drives the segregation of these lineages, providing a framework for self ...
Srinivas, S, Rodriguez, TA
openaire   +5 more sources

Trophoblast lineage specification in the mammalian preimplantation embryo

open access: yesReproductive Medicine and Biology, 2020
Background The establishment of the trophectoderm (TE) and the inner cell mass (ICM) is the first cell lineage segregation that occurs in mammalian preimplantation development. TE will contribute to the placenta while ICM cells give rise to the epiblast (
Yayoi Toyooka
doaj   +1 more source

Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia. [PDF]

open access: yes, 2018
Cell division is essential to expand, shape, and replenish epithelia. In the adult small intestine, cells from a common progenitor intermix with other lineages, whereas cell progeny in many other epithelia form contiguous patches.
Castillo-Azofeifa, David   +7 more
core   +1 more source

In Vitro Host-Cell Susceptibility to Usutu Virus

open access: yesEmerging Infectious Diseases, 2005
We investigated the susceptibility to Usutu virus (Flavivirus) of 13 permanent cell lines, 3 primary cell cultures, and chicken embryos. Vero, PK-15, and goose embryo fibroblast cells developed cytopathic effects; however, viral multiplication was ...
Tamás Bakonyi   +4 more
doaj   +1 more source

Haemogenic endocardium contributes to transient definitive haematopoiesis. [PDF]

open access: yes, 2013
Haematopoietic cells arise from spatiotemporally restricted domains in the developing embryo. Although studies of non-mammalian animal and in vitro embryonic stem cell models suggest a close relationship among cardiac, endocardial and haematopoietic ...
Arshi, Armin   +14 more
core   +1 more source

Embryo splitting

open access: yesMiddle East Fertility Society Journal, 2010
Mammalian embryo splitting has successfully been established in farm animals. Embryo splitting is safely and efficiently used for assisted reproduction in several livestock species.
Karl Illmensee, Mike Levanduski
doaj   +1 more source

The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency

open access: yesNature Communications, 2023
Signal transduction and gene expression regulation via downstream transcription factors shape the early mammalian embryo. Here the authors show that Wnt/TCF7L1 transcriptional repressive activity is required for primitive endoderm lineage formation.
Paraskevi Athanasouli   +19 more
doaj   +1 more source

Embryo metabolism : what does it really mean? [PDF]

open access: yes, 2015
The study of early embryo metabolism has fascinated researchers in the field for nearly a century. Herein, we give a brief account of the general features of embryo metabolism and some consideration of the research performed to reach such conclusions. It
Lewis, Niamh, Sturmey, Roger
core  

Development of Effective Cryopreservation Method for Mammalian Embryo

open access: yesJournal of Animal Reproduction and Biotechnology, 2014
This study was carried out to evaluate the effects of embryonic stage, cryoprotectant, and freezing-thawing method on the rates of survival and development of the cryopreserved mouse early embryo and finally to establish the cryopreservation method of ...
Hyun Kim   +5 more
doaj   +1 more source

Dynamic enlargement and mobilization of lipid droplets in pluripotent cells coordinate morphogenesis during mouse peri-implantation development

open access: yesNature Communications, 2022
Prior to its implantation into the uterus, the mammalian embryo stores substantial lipids. Here the authors unveil how lipid storage and morphogenesis of pluripotent stem cells are fundamentally connected during peri-implantation development.
King Hang Tommy Mau   +12 more
doaj   +1 more source

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