Results 41 to 50 of about 209,877 (288)

NaNog: A pluripotency homeobox (master) molecule. [PDF]

open access: yes, 2015
One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed necessary , then at a specified time can differentiate into any type of cell. This fundamental process
Aguib, YE   +4 more
core   +1 more source

Modeling mammalian gastrulation with embryonic stem cells

open access: yes, 2017
Understanding cell fate patterning and morphogenesis in the mammalian embryo remains a formidable challenge. Recently, in vivo models based on embryonic stem cells (ESCs) have emerged as complementary methods to quantitatively dissect the physical and ...
Amita   +65 more
core   +1 more source

Haemogenic endocardium contributes to transient definitive haematopoiesis. [PDF]

open access: yes, 2013
Haematopoietic cells arise from spatiotemporally restricted domains in the developing embryo. Although studies of non-mammalian animal and in vitro embryonic stem cell models suggest a close relationship among cardiac, endocardial and haematopoietic ...
Arshi, Armin   +14 more
core   +1 more source

The p66(Shc) adaptor protein controls oxidative stress response in early bovine embryos. [PDF]

open access: yesPLoS ONE, 2014
The in vitro production of mammalian embryos suffers from high frequencies of developmental failure due to excessive levels of permanent embryo arrest and apoptosis caused by oxidative stress.
Dean H Betts   +2 more
doaj   +1 more source

Molecular recording of mammalian embryogenesis. [PDF]

open access: yes, 2019
Ontogeny describes the emergence of complex multicellular organisms from single totipotent cells. This field is particularly challenging in mammals, owing to the indeterminate relationship between self-renewal and differentiation, variation in progenitor
Adamson, Britt   +13 more
core   +2 more sources

Molecular and cellular mechanisms underlying the evolution of form and function in the amniote jaw. [PDF]

open access: yes, 2019
The amniote jaw complex is a remarkable amalgamation of derivatives from distinct embryonic cell lineages. During development, the cells in these lineages experience concerted movements, migrations, and signaling interactions that take them from their ...
A Abzhanov   +395 more
core   +1 more source

Reorganization, specialization, and degradation of oocyte maternal components for early development

open access: yesReproductive Medicine and Biology, 2023
Background Oocyte components are maternally provided, solely determine oocyte quality, and coordinately determine embryo quality with zygotic gene expression.
Yuhkoh Satouh, Ken Sato
doaj   +1 more source

Epigenetic regulation in mammalian preimplantation embryo development

open access: yesReproductive Biology and Endocrinology, 2009
Preimplantation embryo development involves four stages: fertilization, cell cleavage, morula and blastocyst formation. During these stages, maternal and zygotic epigenetic factors play crucial roles.
Shi Lingjun, Wu Ji
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Effects of mammalian sex hormones on in vitro organogenesis of common bean (Phaseolus vulgaris L.)

open access: yesScientific Reports, 2023
Beans are an important plant species and are one of the most consumed legumes in human nutrition, especially as a protein, vitamin, mineral, and fiber source.
Kamil Haliloğlu   +5 more
doaj   +1 more source

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