The Alternative Choice of Constitutive Exons throughout Evolution [PDF]
Alternative cassette exons are known to originate from two processes exonization of intronic sequences and exon shuffling. Herein, we suggest an additional mechanism by which constitutively spliced exons become alternative cassette exons during evolution.
Adi Doron-Faigenboim+9 more
core +8 more sources
MELK-a conserved kinase: functions, signaling, cancer, and controversy. [PDF]
Maternal embryonic leucine zipper kinase (MELK) is a highly conserved serine/threonine kinase initially found to be expressed in a wide range of early embryonic cellular stages, and as a result has been implicated in embryogenesis and cell cycle control.
Beullens, Monique+5 more
core +2 more sources
Digital Three-Dimensional Atlas of Quail Development Using High-Resolution MRI [PDF]
We present an archetypal set of three-dimensional digital atlases of the quail embryo based on microscopic magnetic resonance imaging (µMRI). The atlases are composed of three modules: (1) images of fixed ex ovo quail, ranging in age from embryonic day 5
Fraser, Scott E.+6 more
core +3 more sources
The functional significance of residual yolk in lizards [PDF]
Spanish Ministry of Science and Technology [CGL2007-60187/BOS] (...
Braña Vigil, Florentino+5 more
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Female Sex Development and Reproductive Duct Formation Depend on Wnt4a in Zebrafish. [PDF]
In laboratory strains of zebrafish, sex determination occurs in the absence of a typical sex chromosome and it is not known what regulates the proportion of animals that develop as males or females.
Bruce W. Draper+8 more
core +1 more source
Workgroup Report: Incorporating In Vitro Alternative Methods for Developmental Neurotoxicity into International Hazard and Risk Assessment Strategies [PDF]
This is the report of the first workshop on Incorporating In Vitro Alternative Methods for Developmental Neurotoxicity (DNT) Testing into International Hazard and Risk Assessment Strategies, held in Ispra, Italy, on 19–21 April 2005.
Abby Li+36 more
core +3 more sources
Light Activation of the Phosphoinositide Cycle in Intrinsically Photosensitive Chicken Retinal Ganglion Cells [PDF]
Purpose: In vertebrates, intrinsically photosensitive retinal ganglion cells (ipRGCs) acting as nonvisual photoreceptors transmit environmental illumination information to the brain, regulating diverse non–image-forming tasks.
Contin, Maria Ana+5 more
core +1 more source
Ghrelin in Female and Male Reproduction [PDF]
Ghrelin and one of its functional receptors, GHS-R1a (Growth Hormone Secretagogue Receptor 1a), were firstly studied about 15 years. Ghrelin is a multifunctional peptide hormone that affects several biological functions including food intake, glucose ...
Coyral-Castel, Stéphanie+4 more
core +5 more sources
The evolution of IL-4 and IL-13 and their receptor subunits [PDF]
Peer ...
Secombes, Christopher J., Wang, Tiehui
core +1 more source
Selenoprotein gene nomenclature [PDF]
The human genome contains 25 genes coding for selenocysteine-containing proteins (selenoproteins). These proteins are involved in a variety of functions, most notably redox homeostasis.
Arn\ue9r, Elias S.+52 more
core +2 more sources