A short-term chick embryo in vivo xenograft model to study retinoblastoma cancer stem cells
Indian Journal of Ophthalmology, 2022 Purpose: Cancer stem cells (CSCs) reported in various tumors play a crucial role in tumorigenesis and metastasis of retinoblastoma (Rb). Following the efforts to reduce, replace, and refine the use of mammalian models, we aimed to establish a short-term ...
Rohini M Nair +8 more
doaj +1 more source
Digital Three-Dimensional Atlas of Quail Development Using High-Resolution MRI [PDF]
, 2007 We present an archetypal set of three-dimensional digital atlases of the quail embryo based on microscopic magnetic resonance imaging (µMRI). The atlases are composed of three modules: (1) images of fixed ex ovo quail, ranging in age from embryonic day 5
Fraser, Scott E. +6 more
core +3 more sources
MELK-a conserved kinase: functions, signaling, cancer, and controversy. [PDF]
, 2015 Maternal embryonic leucine zipper kinase (MELK) is a highly conserved serine/threonine kinase initially found to be expressed in a wide range of early embryonic cellular stages, and as a result has been implicated in embryogenesis and cell cycle control.
Beullens, Monique +5 more
core +2 more sources
Magnetic Resonance Imaging for Characterization of a Chick Embryo Model of Cancer Cell Metastases
Molecular Imaging, 2018 Metastasis is the most common cause of death for patients with cancer. To fully understand the steps involved in metastatic dissemination, in vivo models are required, of which murine ones are the most common.
Anne Herrmann PhD +4 more
doaj +1 more source
The Alternative Choice of Constitutive Exons throughout Evolution [PDF]
, 2007 Alternative cassette exons are known to originate from two processes exonization of intronic sequences and exon shuffling. Herein, we suggest an additional mechanism by which constitutively spliced exons become alternative cassette exons during evolution.
Adi Doron-Faigenboim +9 more
core +5 more sources
Light Activation of the Phosphoinositide Cycle in Intrinsically Photosensitive Chicken Retinal Ganglion Cells [PDF]
, 2010 Purpose: In vertebrates, intrinsically photosensitive retinal ganglion cells (ipRGCs) acting as nonvisual photoreceptors transmit environmental illumination information to the brain, regulating diverse non–image-forming tasks.
Contin, Maria Ana +5 more
core +1 more source
Seed-produced anti-globulin VHH-Fc antibodies retrieve globulin precursors in the insoluble fraction and modulate the Arabidopsis thaliana seed subcellular morphology [PDF]
, 2020 Key message Nanobody-heavy chain (VHH-Fc) antibody formats have the potential to immunomodulate even highly accumulating proteins and provide a valuable tool to experimentally modulate the subcellular distribution of seed storage proteins.
Altmann, Friedrich +7 more
core +2 more sources
Female Sex Development and Reproductive Duct Formation Depend on Wnt4a in Zebrafish. [PDF]
, 2019 In laboratory strains of zebrafish, sex determination occurs in the absence of a typical sex chromosome and it is not known what regulates the proportion of animals that develop as males or females.
Bruce W. Draper +8 more
core +1 more source
Selenoprotein gene nomenclature [PDF]
, 2016 The human genome contains 25 genes coding for selenocysteine-containing proteins (selenoproteins). These proteins are involved in a variety of functions, most notably redox homeostasis.
Arn\ue9r, Elias S. +52 more
core +3 more sources
The evolution of IL-4 and IL-13 and their receptor subunits [PDF]
, 2015 Peer ...
Secombes, Christopher J., Wang, Tiehui
core +1 more source