Results 161 to 170 of about 338,049 (387)

Rationally Designed TadA‐Derived Cytosine Editors Enable Context‐Independent Zebrafish Genome Editing

open access: yesAdvanced Science, EarlyView.
A next‐generation cytosine base editor (zTadCBE) and other variants are developed by combining the high‐efficiency (TadCBEa) and low‐indel (TadCBEMax) architectures, followed by the introduction of zebrafish‐optimized mutations (V82S, Q154R) in the TadA domain.
Wei Qin   +7 more
wiley   +1 more source

An Opto‐Bio‐Hydrodynamic Platform for Instructing Cardiac Left‐Right Asymmetry Development

open access: yesAdvanced Science, EarlyView.
By establishing mechanistic links among optically tuned ciliary dynamics, flow‐mediated signaling, and organ asymmetry, a multifunctional Opto‐Bio‐Hydrodynamic platform is developed to modulate ciliary motion with the programmable near infrared light for instructing cardiac left‐right asymmetry development in a spatiotemporally controlled manner, which
Haifeng Qin   +8 more
wiley   +1 more source

Biomimetic Chemotactic Motion of Self‐Assembling Doublet Microrobots

open access: yesAdvanced Intelligent Systems, EarlyView.
This article studies the shape‐dependent chemotaxis of different morphologies including self‐assembled doublet microswimmers that exhibit autonomous movement in hydrogen peroxide H2O2 gradients. Without the need for complex material preparation a novel type of chemotactic active matter is produced, which allows the separation of propulsion and cargo ...
Zuyao Xiao   +2 more
wiley   +1 more source

Artificial Intelligences: A Bridge Toward Diverse Intelligence and Humanity's Future

open access: yesAdvanced Intelligent Systems, EarlyView.
Many discussions of artificial intelligence fail to address deeper questions being raised by advances in developmental biology, neuroscience, bioengineering, and philosophy of mind. Novel beings, including technologically and biologically augmented humans, engineered life forms, hybrots, and others, require tools of the emerging field of diverse ...
Michael Levin
wiley   +1 more source

Agrobacterium-mediated barley transformation. [PDF]

open access: yes, 2008
More than ten years have passed since the first successful Agrobacterium-mediated barley transformation experiment, however it is still quite challenging to establish a stably functioning agroinfiltration protocol.
Csóti, László   +2 more
core  

A Population‐Based Study of Limb Body Wall Complex With Proposed Features for Prenatal Diagnosis

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Limb body wall complex (LBWC) is a lethal condition comprising major congenital anomalies. Although currently diagnosed in the early prenatal period, historical diagnostic criteria are based on detailed pathological assessments. Prenatal and postnatal findings of LBWC and their phenotypic overlap with body stalk anomaly (BSA) and recurrent ...
Mary Ann Thomas   +2 more
wiley   +1 more source

Hippo Signaling in Embryogenesis and Development.

open access: yesTIBS -Trends in Biochemical Sciences. Regular ed, 2020
Zhengming Wu, K. Guan
semanticscholar   +1 more source

Neuroaxonal Dystrophy With Osteopetrosis Associated With a Novel Biallelic Nonsense Homozygous Variant in BORCS5

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Neuroaxonal dystrophy (NAD) with osteopetrosis syndrome (OMIM # 600329) was first reported in a consanguineous Moroccan Jewish family. However, to date, no genetic variant has been linked to this disease. We report on sibs, born to consanguineous Pakistani parents identified prenatally with cerebral ventriculomegaly and agenesis of the corpus ...
Yael Fisher   +6 more
wiley   +1 more source

PRIMITIVE ERYTHROPOIESIS IN EARLY CHICK EMBRYOGENESIS [PDF]

open access: bronze, 1971
Graham Le M. Campbell   +3 more
openalex   +1 more source

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