Results 41 to 50 of about 138,368 (322)
Metabolic Contributions of Wnt Signaling: More Than Controlling Flight
Frontiers in Cell and Developmental Biology, 2021 The canonical Wnt signaling pathway is ubiquitous throughout the body and influences a diverse array of physiological processes. Following the initial discovery of the Wnt signaling pathway during wing development in Drosophila melanogaster, it is now ...
Frederic Abou Azar +3 more
doaj +1 more source
Quantifying the mobility of chromatin during embryogenesis: Nuclear size matters [PDF]
arXiv, 2021 Chromatin moves dynamically inside the cell nucleus, and its motion is often correlated with gene functions such as DNA recombination and transcription. A recent study has shown that during early embryogenesis of the nematode, Caenorhabiditis elegans, the chromatin motion markedly decreases. However, the underlying mechanism for this transition has yet
arxiv
Mechanism of DUX-induced differentiation of mESC into extraembryonic endoderm
Shanghai Jiaotong Daxue xuebao. Yixue banObjective·To explore the effect of double homeobox (DUX) protein on the differentiation potential of mouse embryonic stem cells (mESCs) into extraembryonic endoderm (XEN) and the possible mechanism of its action.Methods·Overexpression of DUX cell lines ...
HONG Lei +6 more
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G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst
eLife, 2018 Early mouse development is regulated and accompanied by dynamic changes in chromatin modifications, including G9a-mediated histone H3 lysine 9 dimethylation (H3K9me2).
Jan J Zylicz +6 more
doaj +1 more source
The anomalous tango of hemocyte migration in Drosophila melanogaster embryos [PDF]
arXiv, 2021 Drosophila melanogaster hemocytes are highly motile cells that are crucial for successful embryogenesis and have important roles in the organism's immunological response. Hemocyte motion was measured using selective plane illumination microscopy. Every hemocyte cell in one half of an embryo was tracked during embryogenesis and analysed using a deep ...
arxiv
One-dimensional collective migration of a proliferating cell monolayer [PDF]
Soft Matter 12, 2381-2391 (2016), 2016 The importance of collective cellular migration during embryogenesis and tissue repair asks for a sound understanding of underlying principles and mechanisms. Here, we address recent in vitro experiments on cell monolayers which show that the advancement of the leading edge relies on cell proliferation and protrusive activity at the tissue margin ...
arxiv +1 more source
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source
A high-resolution mRNA expression time course of embryonic development in zebrafish
eLife, 2017 We have produced an mRNA expression time course of zebrafish development across 18 time points from 1 cell to 5 days post-fertilisation sampling individual and pools of embryos.
Richard J White +13 more
doaj +1 more source
Advanced Biology, EarlyView.The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez +8 more
wiley +1 more source
Frontiers in PharmacologyCystathionine γ-lyase (CSE) is a major enzyme that produces hydrogen sulfide (H2S). Herein, we report how CSE plays a previously unknown role in regulating the antioxidant effects of the mitochondria in human umbilical vein endothelial cells by releasing
Tingting Xiao +10 more
doaj +1 more source