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Genome editing reveals a role for OCT4 in human embryogenesis
Despite their fundamental biological and clinical importance, the molecular mechanisms that regulate the first cell fate decisions in the human embryo are not well understood. Here we use CRISPR–Cas9-mediated genome editing to investigate the function of
N. Fogarty+17 more
semanticscholar +1 more source
Sexual Dimorphism in the Age of Genomics: How, When, Where
In mammals, sex chromosomes start to program autosomal gene expression and epigenetic patterns very soon after fertilization. Yet whether the resulting sex differences are perpetuated throughout development and how they connect to the sex-specific ...
Daniel F. Deegan, Nora Engel
doaj +1 more source
Plant embryo development is a complex process that includes several coordinated events. Maize mature embryos consist of a well-differentiated embryonic axis surrounded by a single massive cotyledon called scutellum. Mature embryo axis also includes lateral roots and several developed leaves.
Fontanet, Pilar, Vicient, Carlos M.
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ATACing Somatic Embryogenesis [PDF]
How does auxin induce somatic embryogenesis? In this issue of Developmental Cell, Wang et al. uncover a regulatory role for auxin in the dynamics of chromatin accessibility and gene expression, which is critical for the establishment of developmental time-specific transcriptional regulatory networks orchestrating somatic-to-embryonic cell reprogramming
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In the developing organism, complex molecular programs orchestrate the generation of cells in adequate numbers, drive them to migrate along the correct pathways towards appropriate territories, eliminate superfluous cells, and induce terminal ...
Céline Delloye-Bourgeois+1 more
doaj +1 more source
Desynchronizing Embryonic Cell Division Waves Reveals the Robustness of Xenopus laevis Development
The early Xenopus laevis embryo is replete with dynamic spatial waves. One such wave, the cell division wave, emerges from the collective cell division timing of first tens and later hundreds of cells throughout the embryo.
Graham A. Anderson+3 more
doaj +1 more source
Padrões de acúmulo de proteínas e carboidratos durante a embriogênese somática de Acca sellowiana [PDF]
The aim of this work was to quantify the protein, starch and total sugars levels during histodifferentiation and development of somatic embryos of Acca sellowiana Berg.
Cangahuala-Inocente, Gabriela Claudia+3 more
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Embryogenesis: Anchors away! [PDF]
It has long been appreciated that the oocyte cortex plays a key role in regulating fertilization and establishing embryonic polarity. Recent studies have identified the anti-phosphatase EGG-3 as a cortical anchor for regulatory proteins required for launching embryogenesis in Caenhorhabditis elegans.
David Greenstein, J. Amaranath Govindan
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Brown algae have an important role in marine environments. With respect to their broad distribution and importance for the environment and human use, brown algae of the order Fucales in particular became a model system for physiological and ecological ...
Elena Tarakhovskaya+3 more
doaj +1 more source
Tissue culture of oil palm : finding the balance between mass propagation and somaclonal variation [PDF]
The oil palm (Elaeis guineensis Jacq.) is typically propagated in vitro by indirect somatic embryogenesis, a process in which somatic cells of an explant of choice are, via an intermediate phase of callus growth, induced to differentiate into somatic ...
Inzé, Dirk, Maene, Ludo, Weckx, Sylvie
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