Results 31 to 40 of about 15,439,652 (357)

Embryonic and uterine development during early pregnancy in pigs.

open access: yesJournal of reproduction and fertility. Supplement, 2020
Comparison of the timing of pig preimplantation development, alterations in the ultrastructure of embryonic germ layers, and cytological changes of the uterine epithelial cells leads to the supposition that a close relationship exists between embryonic ...
H. Stroband, T. van der Lende
semanticscholar   +1 more source

Epithelial Mesenchymal Transition in Embryonic Development, Tissue Repair and Cancer: A Comprehensive Overview

open access: yesJournal of Clinical Medicine, 2017
The epithelial mesenchymal transition (EMT) plays a central role in both normal physiological events (e.g., embryonic development) and abnormal pathological events (e.g., tumor formation and metastasis).
Do Hyung Kim   +5 more
semanticscholar   +1 more source

Transcription factor OTX2 silences the expression of cleavage embryo genes and transposable elements

open access: yesThe Journal of Reproduction and Development, 2021
Upon mammalian fertilization, zygotic genome activation (ZGA) and activation of transposable elements (TEs) occur in early embryos to establish totipotency and support embryogenesis.
Shi-meng GUO   +3 more
doaj   +1 more source

Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]

open access: yes, 2019
Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan   +4 more
core   +2 more sources

Reproductive effects of cadmium on sperm function and early embryonic development in vitro

open access: yesPLoS ONE, 2017
Cadmium is a major environmental toxicant that is released into the atmosphere, water and soil in the form of cadmium oxide, cadmium chloride, or cadmium sulfide via industrial activities, such as the manufacturing of batteries and pigments, metal ...
Li-Lin Zhao   +7 more
semanticscholar   +1 more source

Alpha-2-macroglobulin is involved in the occurrence of early-onset pre-eclampsia via its negative impact on uterine spiral artery remodeling and placental angiogenesis

open access: yesBMC Medicine, 2023
Background Pre-eclampsia (PE) is one of the leading causes of maternal and fetal morbidity/mortality during pregnancy, and alpha-2-macroglobulin (A2M) is associated with inflammatory signaling; however, the pathophysiological mechanism by which A2M is ...
Jingyun Wang   +13 more
doaj   +1 more source

ID3 mediates BMP2-induced downregulation of ICAM1 expression in human endometiral stromal cells and decidual cells

open access: yesFrontiers in Cell and Developmental Biology, 2023
Recurrent pregnancy loss (RPL) remains an unsolved problem in obstetrics and gynecology, and up to 50% of RPL cases are unexplained. Unexplained RPL (uRPL) is widely considered to be related to an aberrant endometrial microenvironment.
Jin Luo   +6 more
doaj   +1 more source

A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X. [PDF]

open access: yes, 2008
BackgroundActivated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is
Arruda, VR   +7 more
core   +2 more sources

G-quadruplexes as novel cis-elements controlling transcription during embryonic development

open access: yesNucleic Acids Research, 2016
G-quadruplexes are dynamic structures folded in G-rich single-stranded DNA regions. These structures have been recognized as a potential nucleic acid based mechanism for regulating multiple cellular processes such as replication, transcription and ...
Aldana P David   +5 more
semanticscholar   +1 more source

Genomic instability in individuals with sex determination defects and germ cell cancer

open access: yesCell Death Discovery, 2023
The ability to transmit genetic information through generations depends on the preservation of genome integrity. Genetic abnormalities affect cell differentiation, causing tissue specification defects and cancer.
Maria Krivega   +8 more
doaj   +1 more source

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