Results 31 to 40 of about 14,733,077 (271)

Stages of embryonic development of the zebrafish

open access: yesDevelopmental Dynamics, 1995
We describe a series of stages for development of the embryo of the zebrafish, Danio (Brachydanio) rerio. We define seven broad periods of embryogenesis—the zygote, cleavage, blastula, gastrula, segmentation, pharyngula, and hatching periods.
C. Kimmel   +4 more
semanticscholar   +1 more source

H3K9 demethylase KDM4E is an epigenetic regulator for bovine embryonic development and a defective factor for nuclear reprogramming

open access: yesDevelopment, 2018
Aberrant epigenetic reprogramming often results in developmental defects in somatic cell nuclear transfer (SCNT) embryos during embryonic genome activation (EGA).
Xin Liu   +9 more
semanticscholar   +1 more source

Bioengineering in vitro models of embryonic development [PDF]

open access: yesStem Cell Reports, 2021
Stem cell-based in vitro models of embryonic development have been established over the last decade. Such model systems recapitulate aspects of gametogenesis, early embryonic development, or organogenesis. They enable experimental approaches that have not been possible previously and have the potential to greatly reduce the number of animals required ...
Gupta, Ananya   +3 more
openaire   +4 more sources

Ret kinase-mediated mechanical induction of colon stem cells by tumor growth pressure stimulates cancer progression in vivo

open access: yesCommunications Biology, 2022
Ho-Bouldoires, Sollier, Zamfirov and Broders-Bondon et al. show that high frequency pulsatile mechanical stresses maintain the physiological level of mice colon stem cells through the mechanosensitive Ret kinase and that Ret activation is elevated in ...
Thanh Huong Nguyen Ho-Bouldoires   +18 more
doaj   +1 more source

Embryonic developments [PDF]

open access: yesCurrent Biology, 2009
SummaryAs the UK updates its pioneering Human Fertilisation and Embryology Act, legal boundaries for research in the life sciences are redrawn in other countries as well. Michael Gross reports.
openaire   +2 more sources

Synthesis and maintenance of lipid droplets are essential for mouse preimplantation embryonic development

open access: yesDevelopment, 2019
Lipid droplets (LDs), which are ubiquitous organelles consisting of a neutral lipid core coated with a phospholipid monolayer, play key roles in the regulation of cellular lipid metabolism.
Ryutaro Aizawa   +9 more
semanticscholar   +1 more source

Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors

open access: yesNature Communications, 2018
A role for Slit/Robo signalling in pancreas development has not been defined. Here, the authors generate Robo1/Robo2 knockout mice to identify both as needed for establishing initial pancreatic cell identity as well as for proliferation and survival of ...
Sophie Escot   +4 more
doaj   +1 more source

The Mechanism of Pattern Transitions between Formation and Dispersion [PDF]

open access: yesJournal of Theoretical Biology. 581, 111736 (2024), 2023
The patterns observed on the body surface of living organisms have traditionally been attributed solely to ecological strategies. However, this study investigates a fascinating phenomenon in Pelodiscus sinensis, where patterns formed on the plastron during embryonic and juvenile stages, which are not externally visible, ultimately disappear in ...
arxiv   +1 more source

Structure of the mammalian TRPM7, a magnesium channel required during embryonic development

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Ion channels are pore-forming proteins spanning biological membranes. Transient receptor potential ion channels are a subclass of ion channel proteins, characterized by nonselective permeability to cations such as sodium, calcium, magnesium,
J. Duan   +9 more
semanticscholar   +1 more source

Functional roles of hnRNPA2/B1 regulated by METTL3 in mammalian embryonic development

open access: yesScientific Reports, 2019
Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2/B1) plays an important role in RNA processing via in m6A modification of pre-mRNA or pre-miRNA.
Jeong-woo Kwon   +3 more
semanticscholar   +1 more source

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